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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">grekov</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник хирургии имени И.И. Грекова</journal-title><trans-title-group xml:lang="en"><trans-title>Grekov's Bulletin of Surgery</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0042-4625</issn><publisher><publisher-name>Federal State Budgetary Educational Institution of Higher Education «Academician I.P. Pavlov First St. Petersburg State Medical University» of the Ministry of Healthcare of the Russion Federation, FSBEI HE I.P.Pavlov SPbSMU MOH Russia</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24884/0042-4625-2019-178-4-65-68</article-id><article-id custom-type="elpub" pub-id-type="custom">grekov-1160</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НАБЛЮДЕНИЯ ИЗ ПРАКТИКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>OBSERVATION FROM PRACTICE</subject></subj-group></article-categories><title-group><article-title>ХИРУРГИЧЕСКОЕ ЛЕЧЕНИЕ ГАСТРОИНТЕСТИНАЛЬНОЙ СТРОМАЛЬНОЙ ОПУХОЛИ ДВЕНАДЦАТИПЕРСТНОЙ КИШКИ</article-title><trans-title-group xml:lang="en"><trans-title>Surgical tactics in the treatment of gastrointestinal stromal tumors of the duodenum</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Корольков</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Korolkov</surname><given-names>A. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д-р мед. наук, руководитель отдела общей и неотложной хирургии НИИ хирургии и неотложной медицин</p><p>197022, Россия, Санкт-Петербург, ул. Льва Толстого, д. 6-8</p></bio><bio xml:lang="en"><p>6-8 L’va Tolstogo street, St. Petersburg, Russia, 197022</p></bio><email xlink:type="simple">korolkov.a@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Никитина</surname><given-names>Т. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikitina</surname><given-names>T. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>клинический ординатор кафедры хирургии госпитальной с клиникой</p><p>197022, Россия, Санкт-Петербург, ул. Льва Толстого, д. 6-8</p></bio><bio xml:lang="en"><p>6-8 L’va Tolstogo street, St. Petersburg, Russia, 197022</p></bio><email xlink:type="simple">dr.nikitina11@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Попов</surname><given-names>Д. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Popov</surname><given-names>D. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-хирург хирургического отделения № 4 (неотложной хирургии)</p><p>197022, Россия, Санкт-Петербург, ул. Льва Толстого, д. 6-8</p></bio><bio xml:lang="en"><p>6-8 L’va Tolstogo street, St. Petersburg, Russia, 197022</p></bio><email xlink:type="simple">dimtryP@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Танцев</surname><given-names>А. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Tantsev</surname><given-names>A. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач-хирург хирургического отделения № 4 (неотложной хирургии)</p><p>197022, Россия, Санкт-Петербург, ул. Льва Толстого, д. 6-8</p></bio><bio xml:lang="en"><p>6-8 L’va Tolstogo street, St. Petersburg, Russia, 197022</p></bio><email xlink:type="simple">dr.tantsev@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное образовательное учреждение высшего образования «Первый Санкт-Петербургский государственный медицинский университет имени академика И. П. Павлова»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pavlov University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>28</day><month>08</month><year>2019</year></pub-date><volume>178</volume><issue>4</issue><fpage>65</fpage><lpage>68</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Корольков А.Ю., Никитина Т.О., Попов Д.Н., Танцев А.О., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Корольков А.Ю., Никитина Т.О., Попов Д.Н., Танцев А.О.</copyright-holder><copyright-holder xml:lang="en">Korolkov A.Y., Nikitina T.O., Popov D.N., Tantsev A.O.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.vestnik-grekova.ru/jour/article/view/1160">https://www.vestnik-grekova.ru/jour/article/view/1160</self-uri><abstract><p>Приводится наблюдение из практики – оперативное лечение пациентки с гастроинтестинальной стромальной опухолью (GIST) двенадцатиперстной кишки (ДПК). У пациентки 34 лет, с жалобами на периодически возникающие боли ноющего характера в эпигастральной области, при обследовании было выявлено образование ДПК. Пациентке выполнена резекция передней стенки нисходящей ветви ДПК с опухолью. При патогистологическом исследовании удаленное образование было представлено GIST-опухолью ДПК. При иммуногистохимическом исследовании выявлено, что все клетки образования экспрессируют DOG 1, Vim, CD117, CD34.</p></abstract><trans-abstract xml:lang="en"><p>We present the clinical case of the patient with gastrointestinal stromal tumor of the duodenum (dGIST).The 34-year-old women had complaints of intermittent dull pain located in the upper abdomen. Clinical examination of the abdomen revealed a duodenum tumor. Resection of the anterior wall of the descending part of the duodenum with a tumor was performed. Histopathology reported that the removed neoplasm was represented by GIST of the duodenum. Immunohistochemistry reported that the tumor cells had an expression of DOG 1, Vim, CD117, CD 34.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>опухоль</kwd><kwd>гастроинтестинальная стромальная опухоль</kwd><kwd>диагностика</kwd><kwd>лечение</kwd></kwd-group><kwd-group xml:lang="en"><kwd>tumor</kwd><kwd>gastrointestinal stromal tumor</kwd><kwd>diagnostics</kwd><kwd>treatment</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Серяков А. П. Гастроинтестинальные стромальные опухоли // Рос. журн. гастроэнтерологии, гепатологии и колопроктологии. 2010. № 4. С. 49–57.</mixed-citation><mixed-citation xml:lang="en">Seryakov A. P. Gastrointestinalnye stromalnye opycholi. Rossijskij zhurnal gastrojenterologii, gepatologii i koloproktologii. 2010;(4):49–57. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Miettinen M., Kopczynski J., Makhlouf H. R. et al. Gastrointestinal stromal tumors, intramural leiomyomas and leiomyosarcomas in the duodenum // Am. J. Surg. Pathol. 2003. Vol. 27, № 5. P. 625–641.</mixed-citation><mixed-citation xml:lang="en">Miettinen M., Kopczynski J., Makhlouf H. R. et al. Gastrointestinal stromal tumors, intramural leiomyomas and leiomyosarcomas in the duodenum. Am J Surg Pathol. 2003;27(5):625–641.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Chung J. C., Kim H. C., Chu C. W. Segmental resection with duodenojejunostomy of gastrointestinal stromal tumor involving the duodenum // J. Kor. Surg. Soc. 2011. № 80. P. 12–16.</mixed-citation><mixed-citation xml:lang="en">Miettinen M., Kopczynski J., Makhlouf H. R. et al. Gastrointestinal stromal tumors, intramural leiomyomas and leiomyosarcomas in the duodenum. Am J Surg Pathol. 2003;27(5):625–641.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Buchs N. C., Bucher P., Gervaz P. et al. Segmental duodenectomy for gastrointestinal stromal tumor of the duodenum // World J. Gastroenterol. 2010. Vol. 16, № 22. P. 2788–2792.</mixed-citation><mixed-citation xml:lang="en">Chung J. C., Kim H. C., Chu C. W. Segmental resection with duodenojejunostomy of gastrointestinal stromal tumor involving the duodenum. J. Kor. Surg. Soc. 2011;(80):12–16.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Demetri G. D, Benjamin R. S, Blanke C. D. et al. NCCN Task Force report: management of patients with gastrointestinal stromal tumor (GIST) – update of the NCCN clinical practice guideline // J. Natl. Compr. Canc. Netw. 2007. № 5. P. 1–29.</mixed-citation><mixed-citation xml:lang="en">Chung J. C., Kim H. C., Chu C. W. Segmental resection with duodenojejunostomy of gastrointestinal stromal tumor involving the duodenum. J. Kor. Surg. Soc. 2011;(80):12–16.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Sugase T., Takahashi T., Nakajima K. et al. Clinicopathological characteristics, surgery and survival outcomes of patients with duodenal gastrointestinal stromal tumors // Digestion. 2016. Vol. 94, № 1. P. 30–36.</mixed-citation><mixed-citation xml:lang="en">Buchs N. C., Bucher P., Gervaz P. et al. Segmental duodenectomy for gastrointestinal stromal tumor of the duodenum. World J Gastroenterol. 2010;16(22):2788–2792.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">DeWitt J., Emerson R. E., Sherman S. et al. Endoscopic ultrasoundguided Trucut biopsy of gastrointestinal mesenchymal tumor // Surg. Endosc. 2011. Vol. 25, № 7. P. 2192–2202.</mixed-citation><mixed-citation xml:lang="en">Buchs N. C., Bucher P., Gervaz P. et al. Segmental duodenectomy for gastrointestinal stromal tumor of the duodenum. World J Gastroenterol. 2010;16(22):2788–2792.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Uçar A. D., Oymaci E., Carti E. B. et al. Characteristics of emergency gastrointestinal stromal tumor (GIST) // Hepatogastroent. 2015. Vol. 62, № 132. P. 635–640.</mixed-citation><mixed-citation xml:lang="en">Demetri G. D, Benjamin R. S, Blanke C. D. et al. NCCN Task Force report: management of patients with gastrointestinal stromal tumor (GIST) – update of the NCCN clinical practice guideline. J Natl  Compr Canc Netw. 2007;(5):1–29.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Kurihara N., Kikuchi K., Tanabe M. et al. Partial resection of the second portion of</mixed-citation><mixed-citation xml:lang="en">Demetri G. D, Benjamin R. S, Blanke C. D. et al. NCCN Task Force report: management of patients with gastrointestinal stromal tumor (GIST) – update of the NCCN clinical practice guideline. J Natl  Compr Canc Netw. 2007;(5):1–29.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">the duodenum for gastrointestinal stromal tumor after effective transarterial embolization // Int. J. Clin. Oncol. 2005. Vol. 10, № 6. P. 433–437.</mixed-citation><mixed-citation xml:lang="en">Sugase T., Takahashi T., Nakajima K. et al. Clinicopathological characteristics, surgery and survival outcomes of patients with duodenal gastrointestinal stromal tumors. Digestion. 2016;94(1):30–36.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Beham A., Schaefer I. M., Cameron S. et al. Duodenal GIST : a single center experience // Int. J. Colorectal. Dis. 2013. Vol. 28, № 4. P. 581–590.</mixed-citation><mixed-citation xml:lang="en">Sugase T., Takahashi T., Nakajima K. et al. Clinicopathological characteristics, surgery and survival outcomes of patients with duodenal gastrointestinal stromal tumors. Digestion. 2016;94(1):30–36.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">DeWitt J., Emerson R. E., Sherman S. et al. Endoscopic ultrasoundguided Trucut biopsy of gastrointestinal mesenchymal tumor. Surg Endosc. 2011;25(7):2192–2202.</mixed-citation><mixed-citation xml:lang="en">DeWitt J., Emerson R. E., Sherman S. et al. Endoscopic ultrasoundguided Trucut biopsy of gastrointestinal mesenchymal tumor. Surg Endosc. 2011;25(7):2192–2202.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">DeWitt J., Emerson R. E., Sherman S. et al. Endoscopic ultrasoundguided Trucut biopsy of gastrointestinal mesenchymal tumor. Surg Endosc. 2011;25(7):2192–2202.</mixed-citation><mixed-citation xml:lang="en">DeWitt J., Emerson R. E., Sherman S. et al. Endoscopic ultrasoundguided Trucut biopsy of gastrointestinal mesenchymal tumor. Surg Endosc. 2011;25(7):2192–2202.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Uçar A. D., Oymaci E., Carti E. B. et al. Characteristics of emergency gastrointestinal stromal tumor (GIST). Hepatogastroent. 2015; 62(132):635–640.</mixed-citation><mixed-citation xml:lang="en">Uçar A. D., Oymaci E., Carti E. B. et al. Characteristics of emergency gastrointestinal stromal tumor (GIST). Hepatogastroent. 2015; 62(132):635–640.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Uçar A. D., Oymaci E., Carti E. B. et al. Characteristics of emergency gastrointestinal stromal tumor (GIST). Hepatogastroent. 2015; 62(132):635–640.</mixed-citation><mixed-citation xml:lang="en">Uçar A. D., Oymaci E., Carti E. B. et al. Characteristics of emergency gastrointestinal stromal tumor (GIST). Hepatogastroent. 2015; 62(132):635–640.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Kurihara N., Kikuchi K., Tanabe M. et al. Partial resection of the second portion of the duodenum for gastrointestinal stromal tumor after effective transarterial embolization. Int J Clin Oncol. 2005;10(6):433–437.</mixed-citation><mixed-citation xml:lang="en">Kurihara N., Kikuchi K., Tanabe M. et al. Partial resection of the second portion of the duodenum for gastrointestinal stromal tumor after effective transarterial embolization. Int J Clin Oncol. 2005;10(6):433–437.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Kurihara N., Kikuchi K., Tanabe M. et al. Partial resection of the second portion of the duodenum for gastrointestinal stromal tumor after effective transarterial embolization. Int J Clin Oncol. 2005;10(6):433–437.</mixed-citation><mixed-citation xml:lang="en">Kurihara N., Kikuchi K., Tanabe M. et al. Partial resection of the second portion of the duodenum for gastrointestinal stromal tumor after effective transarterial embolization. Int J Clin Oncol. 2005;10(6):433–437.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Beham A., Schaefer I. M., Cameron S. et al. Duodenal GIST: a single center experience. Int J Colorectal Dis. 2013;28(4):581–590.</mixed-citation><mixed-citation xml:lang="en">Beham A., Schaefer I. M., Cameron S. et al. Duodenal GIST: a single center experience. Int J Colorectal Dis. 2013;28(4):581–590.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Beham A., Schaefer I. M., Cameron S. et al. Duodenal GIST: a single center experience. Int J Colorectal Dis. 2013;28(4):581–590.</mixed-citation><mixed-citation xml:lang="en">Beham A., Schaefer I. M., Cameron S. et al. Duodenal GIST: a single center experience. Int J Colorectal Dis. 2013;28(4):581–590.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Beham A., Schaefer I. M., Cameron S. et al. Duodenal GIST: a single center experience. Int J Colorectal Dis. 2013;28(4):581–590.</mixed-citation><mixed-citation xml:lang="en">Beham A., Schaefer I. M., Cameron S. et al. Duodenal GIST: a single center experience. Int J Colorectal Dis. 2013;28(4):581–590.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
