grekovВестник хирургии имени И.И. ГрековаGrekov's Bulletin of Surgery0042-4625Federal State Budgetary Educational Institution of Higher Education «Academician I.P. Pavlov First St. Petersburg State Medical University» of the Ministry of Healthcare of the Russion Federation, FSBEI HE I.P.Pavlov SPbSMU MOH Russia10.24884/0042-4625-2020-179-3-100-106grekov-1237Research ArticleОБЗОРЫREVIEWSПроблемы выполнения аортокоронарного шунтирования после предварительного стентирования коронарных артерий в связи с острым коронарным синдромом (обзор литературы)Problems of performing coronary artery bypass grafting after preliminary stenting of coronary arteries due to acute coronary syndrome (review of literature)БигашевА. Р.BigashevA. R.

Бигашев Андрей Рашитович, врач – сердечно-сосудистый хирург

192242, Санкт-Петербург, ул. Будапештская, д. 3, лит. А.

Bigashev Andrey R., Cardio-Vascular Surgeon

3, Budapeshtskaya str., Saint Petersburg, 192242, Russia.

firetempest@yandex.ruШихвердиевН. Н.ShikhverdievN. N.

Шихвердиев Назим Низамович, доктор медицинских наук, профессор

Санкт-Петербург

Shikhverdiev Nazim N., Dr. of Sci. (Med.), Professor

Saint Petersburg

nazniz@mail.ruhttps://orcid.org/0000-0002-6977-611XПелешокА. С.PeleshokA. S.

Пелешок Андрей Степанович, кандидат медицинских наук, доцент

Санкт-Петербург

Peleshok Andrey S., Cand. of Sci. (Med.), Associate Professor

Saint Petersburg

aspeleshok1976@gmail.comСорокаВ. В.SorokaV. V.

Сорока Владимир Васильевич, доктор медицинских наук, профессор

Санкт-Петербург

Soroka Vladimir V., Dr. of Sci. (Med.), Professor

Saint Petersburg

soroka@emergency.spb.ruГосударственное бюджетное учреждение «Санкт-Петербургский научно-исследовательский институт имени И. И. Джанелидзе»РоссияSaint-Petersburg I. I. Dzhanelidze Research Institute of Emergency MedicineRussian FederationФедеральное государственное бюджетное военное образовательное учреждение высшего образования «Военно-медицинская академия имени С. М. Кирова» Министерства обороны Российской ФедерацииРоссияMilitary Medical AcademyRussian Federation2020140520201793100106Copyright © Бигашев А.Р., Шихвердиев Н.Н., Пелешок А.С., Сорока В.В., 20202020Бигашев А.Р., Шихвердиев Н.Н., Пелешок А.С., Сорока В.В.Bigashev A.R., Shikhverdiev N.N., Peleshok A.S., Soroka V.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.vestnik-grekova.ru/jour/article/view/1237

Целью данной статьи является анализ современных работ об особенности выполнения аортокоронарного шунтирования (АКШ) у пациентов, первично подвергшихся интралюминальной ангиопластике и стентированию в связи с острым коронарным синдромом. Несмотря на неоспоримое преимущество стентирования у пациентов с острым коронарным синдромом (ОКС), до сих пор остается большое число неразрешенных вопросов у данной категории больных, в особенности, когда данные пациенты, ранее стентированные в связи с ОКС, подвергаются аортокоронарному шунтированию в связи с повторным эпизодом ОКС. Тактика ведения и подготовки пациентов, поступивших повторно для коронарного шунтирования после предварительного стентирования, до сих пор остается не ясной, в связи с чем сохраняется значительное число нерешенных вопросов при выполнении АКШ на фоне повторного развития ОКС с предварительно уже скомпрометированным сосудистым руслом и наличием хронического воспаления в коронарных артериях. Остаются открытыми и вопросы о возникновении периоперационных и послеоперационных осложнений у данной категории больных. Мы проанализировали последние работы и исследования по данной проблеме с помощью поисковых систем «NLM», «Google Scholar», «E-library». В связи с создавшейся ситуацией массового использования стентирования остаются открытыми ряд вопросов (время отмены двойной дезагрегантной терапии, необходимость шунтирования ранее стентированного сосуда, возможность выполнения комбинированного метода лечения ОКС). Информации о необходимости шунтирования ранее стентированной коронарной артерии в сроки более ранние, чем указано в европейских рекомендациях, крайне мало.

The objective of this article was to analyze current researches on the peculiarities of performing coronary artery bypass grafting in patients who primarily underwent intraluminal angioplasty and stenting due to acute coronary syndrome. Despite the priority of stenting in patients with acute coronary syndrome (ACS), there is still a significant number of unresolved issues in this category of patients, especially when these patients, previously stenting due to ACS, undergo coronary artery bypass grafting due to a repeated ACS case. The tactics of management and preparation of patients who were admitted for repeated CABG after preliminary stenting are still not clear, and therefore, a significant number of unresolved issues remains when performing CABG against the background of repeated ACS cases with a previously compromised vascular bed and the presence of chronic inflammation in the coronary arteries. Questions about the perioperative and postoperative complications in this category of patients remain open. We analyzed the latest works and researches about that problem using such systems as NLM, Google Scholar and Elibrary. Due to the current situation of mass use of stenting, a number of questions remain open (the time of cancellation of double disaggregation therapy, the need for shunting the previously stented vessel, the possibility of performing a combined method of treatment for ACS). There is a very little information on the need to bypass the previously stented coronary artery at an earlier date than indicated in the European recommendations.

острый коронарный синдромаортокоронарное шунтированиедвойная дезагрегантная терапиячрескожные коронарные вмешательстваишемическая болезнь сердцаacute coronary syndromecoronary artery bypass graftdouble disaggregation therapypercutaneous coronary interventioncoronary heart diseaseReferencesСтабильная ишемическая болезнь сердца. Клинические рекомендации. 2016. С. 4–5.Stabil’naya ishemicheskaya bolezn’ serdtsa. Klinicheskie rekomendatsii. 2016:4–5. (In Russ.).Mohr F. W., Morice M. C., Kappetein A. P. et al. Coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with three-vessel disease and left main coronary disease : 5-year follow-up of the randomized, clinical SYNTAX trial // Lancet. 2013. Vol. 381, № 9867. P. 629–638.Mohr F. W., Morice M. C., Kappetein A. P. et al. Coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with three-vessel disease and left main coronary disease: 5-year follow-up of the randomized, clinical SYNTAX trial. Lancet. 2013;381(9867):629–638.Nabel E. G., Braunwald E. A Tale of Coronary Artery Disease and Myocardial Infarction // N. Engl. J. Med. 2012. Vol. 366, № 1. P. 54–63.Nabel E. G., Braunwald E. A Tale of Coronary Artery Disease and Myocardial Infarction. N Engl J Med. 2012;366(1):54–63.Epstein A. J., Polsky D., Yang F. et al. Coronary revascularization trends in the United States: 2001–2008 // JAMA. 2011. Vol. 305, № 17. P. 1769–1776.Epstein A. J., Polsky D., Yang F., Yang L., Groeneveld P. W. Coronary revascularization trends in the United States: 2001–2008. JAMA. 2011;305(17):1769–1776.Соколова С. О., Мазаев В. П., Попов Ю. М. и др. Стентирование коронарных артерий при остром коронарном синдроме // Общая реаниматология. 2006. Т. 2, № 1. С. 32–38.Sokolova S. O., Mazayev V. P., Popov Y. M., Ryazanova S. V., Kuznetsova G. V. Stentirovanie koronarnyh arterij pri ostrom koronarnom sindrome. Obshhaja reanimatologija. 2006;2(1):32–38. (In Russ.).Stone G. W., Sabik J. F., Serruys P. W. et al. Everolimus-Eluting Stents or Bypass Surgery for Left Main Coronary Artery Disease // N. Engl. J. Med. 2016. Vol. 375, № 23. P. 2223–2235.Stone G. W., Sabik J. F., Serruys P. W. et al. Everolimus-Eluting Stents or Bypass Surgery for Left Main Coronary Artery Disease. N Engl. J. Med. 2016;375(23):2223–2235.Athappan G., Patvardhon E., Tuzu M. E. et al. Left main coronary artery stenosis a meta-analysis of drug-eluting stents versus CABG // JACC Cardiovasc. Interv. 2013. Vol. 6, № 12. P. 1219–1230.Athappan G., Patvardhon E., Tuzu M. E., Ellis S., Whitlow P., Hapadia S. R. Left main coronary artery stenosis a meta-analysis of drug-eluting stents versus CABG. JACC Cardiovasc Interv. 2013;6(12):1219–1230.Windecker S., Kolh P., Alfonso f. et al. 2014 ESC/EACTS Guidelines on Myocardial Revascularization : The Task Society of Myocardial Revascularization of the European Association for Cardiology (ESC) and the European Association for Cardio Thoracic Surgery (EACTS) Developed with the special contribution of the European Association of Percutaneous Cardiovascular Interventions (EAPCI) // Eur. Heart J. 2014. Vol. 35, № 37. P. 2541–2619.Windecker S., Kolh P., Alfonso f. el аl. 2014 ESC/EACTS Guidelines on Myocardial Revascularization: The Task Society of Myocardial Revascularization of the European Association for Cardiology (ESC) and the European Association for Cardio Thoracic Surgery (EACTS) Developed with the special contribution of the European Association of Percutaneous Cardiovascular Interventions (EAPCI). Eur Heart J. 2014;35(37):2541–2619.Кузнецов В. А., Ярославская В. И., Пушкарев Г. С. и др. Взаимосвязь чрезкожных коронарных вмешательств при острых формах ишемической болезни сердца и показателей смертности населения Тюменской области // Рос. кардиол. журн. 2014. Т. 6, № 110. С. 42–46.Kuznetsov V. A., Yaroslavskaya V. I., Pushkarev G. S. et al. Vzaimosvyaz’ chrezkozhnykh koronarnykh vmeshatel’stv pri ostrykh formakh ishemicheskoi bolezni serdtsa i pokazatelei smertnosti naseleniya Tyumenskoi oblasti. Rossiiskii kardiologicheskii zhurnal. 2014;6(110):42–46. (In Russ.).Бокерия Л. А., Гудкова Р. Г. Сердечно-сосудистая хирургия – 2014. Болезни и врожденные аномалии системы кровообращения. М. : Изд-во НЦССХ им. А. Н. Бакулева РАМН, 2014; 2015. 225 с.Bokeriya L. A., Gudkova R. G. Serdechno-sosudistaya khirurgiya – 2014. Bolezni i vrozhdennye anomalii sistemy krovoobrashcheniya. Moscow, Nauchnyy Tsentr serdechno-sosudistoy khirurgii im. A. N. Bakuleva RAMN, 2014:228. (In Russ.).Бокерия Л. А., Керен М. А., Енокян Л. Г. и др. Отдаленные результаты аортокоронарного шунтирования у больных ишемической болезнью сердца пожилого и старческого возраста // Анналы хир. 2012. № 2. С. 15–21.Bokeriya L. A., Keren M. A., Enokyan L. G. et al. Otdalennye rezul’taty aortokoronarnogo shuntirovaniya u bol’nykh ishemicheskoi bolezn’yu serdtsa pozhilogo i starcheskogo vozrasta. Annaly khirurgii. 2012;2:15–21. (In Russ.).Бокерия Л. А., Алекян Б. Г. Рентгенэндоваскулярная диагностика и лечение заболеваний сердца и сосудов в Российской Федерации – 2014. М. : НЦССХ им. А. Н. Бакулева РАМН, 2015. 180 с.Bokerija L. A., Alekjan B. G. Rentgenjendovaskuljarnaja diagnosti ka i lechenie zabolevanij serdca i sosudov v Rossijskoj Federacii – 2014. Moscow, Nauchnyy Tsentr serdechno-sosudistoy khirurgii im. A. N. Bakuleva RAMN, 2015:180. (In Russ.).Wald D. S., Morrus J. K., Wald N. J. et al. Prami Investigators Randomized Trial of Preventive Angioplasty in Miocardial Infarction // N. Engl. J. Med. 2013. Vol. 369, № 12. P. 1115–1123.Wald D. S., Morrus J. K., Wald N. J. et al. Prami Investigators Randomized Trial of Preventive Angioplasty in Miocardial Infarction. N Engl J Med. 2013;369(12):1115–1123.Degertekin M., Regar E., Tanabe K. et al. Sirolimus eluting stent in the treatment of atherosclerosis coronary artery disease // Minerva Cardioangiol. 2002. Vol. 50, № 5. P. 405–418.Degertekin M., Regar E., Tanabe K. et al. Sirolimus eluting stent in the treatment of atherosclerosis coronary artery disease. Minerva Cardioangiol. 2002;50(5):405–418.Бокерия Л. А., Гудкова Р. Г. Сердечно-сосудистая хирургия – 2011. Болезни и врожденные аномалии системы кровообращения. М. : НЦССХ им. А. Н. Бакулева РАМН, 2012. 196 с.Bokeriya L. A., Gudkova R. G. Serdechno-sosudistaya khirurgiya – 2011. Bolezni i vrozhdennye anomalii sistemy krovoobrashcheniya. Moscow, Nauchnyy Tsentr serdechno-sosudistoy khirurgii im. A. N. Bakuleva RAMN, 2012:196. (In Russ.).Barakate M. S., Hemli J. M., Hughes C. F. et al. Coronary artery bypass grafting (CABG) after initially successful percutaneous transluminal coronary angioplasty (PTCA) : a review of 17 years experience // Eur. J. Cardiothorac. Surg. 2003. Vol. 23, № 2. P. 179–186.Barakate M. S., Hemli J. M., Hughes C. F., Bannon P. G., Horton M. D. Coronary artery bypass grafting (CABG) after initially successful percutaneous transluminal coronary angioplasty (PTCA): a review of 17 years experience. Eur J Cardiothorac Surg. 2003;23(2):179–186.Hoffman S. N., TenBrook J. A., Wolf M. P. et al. A meta-analysis of randomized controlled trials comparing coronary artery bypass graft with percutaneous transluminal coronary angioplasty : one-to eight-year outcomes // J. Am. Coll. Cardiol. 2003. Vol. 41, № 8. P. 1293–1304.Hoffman S. N., TenBrook J. A., Wolf M. P. et al. A meta-analysis of randomized controlled trials comparing coronary artery bypass graft with percutaneous transluminal coronary angioplasty: one-to eight-year out-comes. J Am Coll Cardiol. 2003;41(8):1293–1304.Abbott J. D., Voss A. R., Nakamura M. et al. Unrestricted use of drugeluting stents compared with bare-metal stents in routine clinical practice // J. Am. Coll. Cardiol. 2007. Vol. 50, № 21. P. 2029–2036.Abbott J. D., Voss A. R., Nakamura M. et al. Unrestricted use of drugeluting stents compared with bare-metal stents in routine clinical practice. J Am Coll Cacrdiol. 2007;50(21):2029–2036.Mercado N., Wijns W., Serruys P. W. et al. One-year outcomes of coronary artery bypass graft surgery versus percutaneous coronary intervention with multiple stenting for multisystem disease : a meta-analysis of individual patient data from randomized clinical trials // J. Thorac. Cardiovasc. Surg. 2005. Vol. 130, № 2. P. 512–519.Mercado N., Wijns W., Serruys P. W. et al. One-year outcomes of coronary artery bypass graft surgery versus percutaneous coronary intervention with multiple stenting for multisystem disease: a meta-analysis of individual patient data from randomized clinical trials // J Thorac Cardiovasc Surg. 2005;130(2):512–519.Chocron S., Baillot R., Rouleau J. L. et al. Impact of previous percutaneous transluminal coronary angioplasty and/or stenting revascularization on outcomes after surgical revascularization : insights from the imagine study // Eur. Heart. J. 2008. Vol. 29, № 5. P. 673–679.Chocron S., Baillot R., Rouleau J. L. et al. Impact of previous percutaneous transluminal coronary angioplasty and/or stenting revascularization on outcomes after surgical revascularization: insights from the imagine study. Eur Heart J. 2008;29(5):673–679.Warnica J. W., Gilst W. V., Baillot R. et al. Ischemia Management with Accupril post bypass Graft via Inhibition of angiotensin converting enzyme (IMAGINE) : a multicentre randomized trial–design and rationale // Can. J. Cardiol. 2002. Vol. 18, № 11. P. 1191–1200.Warnica J. W., Gilst W. V., Baillot R. et al. Ischemia Management with Accupril post bypass Graft via Inhibition of angiotensin converting enzyme (IMAGINE): a multicentre randomized trial–design and rationale. Can J Cardiol. 2002;18(11):1191–1200.Hassan A., Buth K. J., Baskett R. J. et al. The association between prior percutaneous coronary intervention and short-term outcomes after coronary artery bypass grafting // Am. Heart J. 2005. Vol. 150, № 5. P. 1026–1031.Hassan A., Buth K. J., Baskett R. J. et al. The association between prior percutaneous coronary intervention and short-term outcomes after coronary artery bypass grafting. Am Heart J. 2005;150(5):1026–1031.Mannacio V., Tommaso Di L., Amicis De V. et al. Previous percutaneous coronary interventions increase mortality and morbidity after coronary surgery // Ann. Thorac. Surg. 2012. Vol. 93, № 6. P. 1956–1962.Mannacio V., Tommaso Di L., Amicis De V. et al. Previous percutaneous coronary interventions increase mortality and morbidity after coronary surgery. Ann Thorac. Surg. 2012;93(6):1956–1962.Eifert S., Mair H., Boulesteix A. L. et al. Mid-term outcomes of patients with PCI prior to CABG in comparison to patients with primary CABG // Vasc. Health Risk Manag. 2010. № 6. P. 495–501.Eifert S., Mair H., Boulesteix A. L. et al. Mid-term outcomes of patients with PCI prior to CABG in comparison to patients with primary CABG. Vasc Health Risk Manag. 2010;6:495–501.Yap C. H., Yan B. P., Akowuah E. et al. Does prior percutaneous coronary intervention adversely affect early and mid-term survival after coronary artery surgery? // JACC Cardiovasc. Interv. 2009. Vol. 2, № 8. P. 758–764.Yap C. H., Yan B. P., Akowuah E. et al. Does prior percutaneous coronary intervention adversely affect early and mid-term survival after coronary artery surgery? JACC Cardiovasc Interv. 2009;2(8):758–764.Gomes W. J., Buffolo E. Coronary stenting and inflammation : implications for further surgical and medical treatment // Ann. Thorac. Surg. 2006. Vol. 81, № 5. P. 1918–1925.Gomes W. J., Buffolo E. Coronary stenting and inflammation: implications for further surgical and medical treatment. Ann Thorac Surg. 2006; 81(5):1918–1925.Toutouzas K., Colombo A., Stefanadis C. Inflammation and restenosis after percutaneous coronary interventions // Eur. Heart J. 2004. Vol. 25, № 19. P. 1679–1687.Toutouzas K., Colombo A., Stefanadis C. Inflammation and restenosis after percutaneous coronary interventions. Eur Heart J. 2004;25(19):1679–1687.Wykretowicz A., Dziarmaga M., Szczepanik A. et al. Prospective evaluation of hydroperoxide plasma levels and stable nitric oxide end products in patients subjected to angioplasty for coronary artery disease // Int. J. Cardiol. 2003. Vol. 89, № 2–3. P. 173–178.Wykretowicz A., Dziarmaga M., Szczepanik A. et al. Prospective evaluation of hydroperoxide plasma levels and stable nitric oxide end products in patients subjected to angioplasty for coronary artery disease. Int J Cardiol. 2003;89(2–3):173–178.Nickenig G., Sinning J. M. Response to drug-eluting stents do we need drugs to recompense drug elution? // J. Am. Coll. Cardiol. 2009. Vol. 54, № 24. P. 2330–2332.Nickenig G., Sinning J. M. Response to drug-eluting stents do we need drugs to recompense drug elution? J Am Coll Cardiol. 2009;54(24):2330–2332.Hofma S. H., Giessen W. J. van der, Dalen B. M. van et al. Indication of long-term endothelial dysfunction after sirolimus-eluting stent implantation // Eur. Heart J. 2006. Vol. 27, № 2. P. 166–170.Hofma S. H., Giessen W. J. van der, Dalen B. M. van et al. Indication of long-term endothelial dysfunction after sirolimus-eluting stent implantation. Eur Heart J. 2006;27(2):166–170.Togni M., Windecker S., Cocchia R. et al. Sirolimus-eluting stents as sociated with paradoxic coronary vasoconstriction // J. Am. Coll. Cardiol. 2005. Vol. 46, № 2. P. 231–236.Togni M., Windecker S., Cocchia R. et al. Sirolimus-eluting stents as so ciated with paradoxic coronary vasoconstriction. J Am Coll Cardiol. 2005;46(2):231–236.Gomes W. J., Giannotti-Filho O., Hossne N. A. Jr. et al. Inflammatory reaction after sirolimus-eluting stent implant // Ann. Thorac. Surg. 2005. Vol. 80, № 5. P. 1903–1904.Gomes W. J., Giannotti-Filho O., Hossne N. A. Jr. et al. Inflammatory reaction after sirolimus-eluting stent implant. Ann Thorac Surg. 2005; 80(5):1903–1904.Chikara U., Genichi S., Takehide A. et al. Influence of previous percutaneous coronary intervention on clinical outcome of coronary artery bypass grafting : a metaanalysis of comparative studies // Interact. Cardiovasc. Thorac. Surg. 2015. Vol. 20, № 4. P. 531–537.Chikara U., Genichi S., Takehide A., Tsunehiro S., Yuko O., Hirofumi S. Influence of previous percutaneous coronary intervention on clinical outcome of coronary artery bypass grafting: a metaanalysis of comparative studies. Interact Cardiovasc Thorac Surg. 2015;20(4):531–537; discussion 537.Hannan E. L., Racz M. J., Walford G. et al. Long-term outcomes of co ronaryartery bypass grafting versus stent implantation // N. Engl. J. Med. 2005. Vol. 352, № 21. P. 2174–2183.Hannan E. L., Racz M. J., Walford G., Jones R. H., Ryan T. J., Bennett E., Culliford A. T., Isom O. W., Gold J. P., Rose E. A. Long-term outcomes of coronary-artery bypass grafting versus stent implantation. N Engl J Med. 2005;352(21):2174–2183.Soylu E., Harling L., Ashrafian H. et al. Adjunct coronary endarterectomy increases myocardial infarction and early mortality after coronary artery bypass grafting : a meta-analysis // Interact. Cardiovasc. Thorac. Surg. 2014. Vol. 19, № 3. P. 462–473.Soylu E., Harling L., Ashrafian H., Casula R., Kokotsakis J., Athanasiou T. Adjunct coronary endarterectomy increases myocardial infarction and early mortality after coronary artery bypass grafting: a meta-analysis. Interact Cardiovasc Thorac Surg. 2014;19(3):462–473.Sakaguchi G., Shimamoto T., Komiya T. Impact of repeated percutaneous coronary intervention on long-term survival after subsequent coronary artery bypass surgery // J. Cardiothorac. Surg. 2011. Vol. 6, № 107. P. 1–4.Sakaguchi G., Shimamoto T., Komiya T. Impact of repeated percutaneous coronary intervention on long-term survival after subsequent coronary artery bypass surgery. J Cardiothorac Surg. 2011;6(107):1–4.Taggart D. P. Coronary artery bypass graft vs. percutaneous coronary angioplasty : CABG on the rebound? // Curr. Opin. Cardiol. 2007. Vol. 22, № 6. P. 517–523.Taggart D. P. Coronary artery bypass graft vs. percutaneous coronary angioplasty: CABG on the rebound? Curr Opin Cardiol. 2007;22(6): 517–523.Mohr F. W., Rastan A. J., Serruys P. W. et al. Complex coronary anatomy in coronary artery bypass graft surgery : Impact of complex coronary anatomy in modern bypass surgery? Lessons learned from the SYNTAX trial after two years // J. Thorac. Cardiovasc. Surg. 2011. Vol. 141, № 1. P. 130–140.Mohr F. W., Rastan A. J., Serruys P. W. et al. Complex coronary anatomy in coronary artery bypass graft surgery: Impact of complex coronary anatomy in modern bypass surgery? Lessons learned from the SYNTAX trial after two years. J Thorac Cardiovasc Surg. 2011;141(1):130–140.Aldea G. S., Bakaeen F. G., Pal J. et al. The Society of Thoracic Surgeons clinical practice guidelines on arterial conduits for coronary artery bypass grafting //Ann. Thorac. Surg. 2016. Vol. 101, № 2. P. 801–809.Aldea G. S., Bakaeen F. G., Pal J., Fremes S., Head S. J., Sabik J., Rosengart T., Kappetein A. P., Thourani V. H., Firestone S., Mitchell J. D. The Society of Thoracic Surgeons clinical practice guidelines on arterial conduits for coronary artery bypass grafting. Ann Thorac Surg. 2016;101(2):801–809.Head S. J., Parasca C. A., Mack M. J. et al. Differences in baseline characteristics, practice patterns and clinical outcomes in contemporary coronary artery bypass grafting in the United States and Europe: insights from the SYNTAX randomized trial and registry // Eur. J. Cardiothorac. Surg. 2015. Vol. 47, № 4. P. 685–695.Head S. J., Parasca C. A., Mack M. J. et al. Differences in baseline cha racteristics, practice patterns and clinical outcomes in contemporary coronary artery bypass grafting in the United States and Europe: insights from the SYNTAX randomized trial and registry. Eur J Cardiothorac Surg. 2015;47(4):685–695.Soylu E., Harling L., Ashrafian H. et al. Adjunct coronary endarterectomy increases myocardial infarction and early mortality after coronary artery bypass grafting : a meta-analysis // Interactive CardioVascular and Thoracic Surgery. 2014. Vol. 19, № 3. P. 462–473.Soylu E., Harling L., Ashrafian H., Casula R., Kokotsakis J., Athanasiou T. Adjunct coronary endarterectomy increases myocardial infarction and early mortality after coronary artery bypass grafting: a meta-analysis. Interactive CardioVascular and Thoracic Surgery. 2014;19(3):462–473.Jessen C., Sharma R. Use fibrin glue in thoracic surgery // Ann. Thorac. Surg. 1985. Vol. 39, № 6. P. 521–524.Jessen C., Sharma R. Use fibrin glue in thoracic surgery. Ann Thorac Surg. 1985;39(6):521–524.Kim J. H., Newby L. K., Clare R. M. et al. Clopidogrel use and bleeding after coronary artery bypass graft surgery // Am. Heart J. 2008. Vol. 156, № 5. P. 886–892.Kim J. H., Newby L. K., Clare R. M., Shaw L. K., Lodge A. J., Smith P. K. et al. Clopidogrel use and bleeding after coronary artery bypass graft surgery. Am. Heart J. 2008;156(5):886–892.Fox K. A., Mehta S. R., Peters R. et al.: Benefits and risks of the combination of clopidogrel and aspirin in patients undergoing surgical revascularization for non-ST-elevation acute coronary syndrome : the Clopidogrel in Unstable angina to prevent Recurrent ischemic Events (CURE) Trial. Circulation. 2004. Vol. 110, № 10. P. 1202–1208.Fox K. A., Mehta S. R., Peters R. et al. Benefits and risks of the combination of clopidogrel and aspirin in patients undergoing surgical revascularization for non-ST-elevation acute coronary syndrome: the Clopidogrel in Unstable angina to prevent Recurrent ischemic Events (CURE) Trial. Circulation. 2004;110(10):1202–1208.Шихвердиев Н. Н., Бигашев А. Р., Егикян Л. Д. Влияние времени отмены двойной дезагрегантной терапии в предоперационном периоде на частоту рестернотомий после аортокоронарного шунтирования // Клин. и эксперим. хир. Журн. им. акад. Б. В. Петровского. 2018. № 1. С. 34–38.Shikhverdiev N. N., Bigashev A. R., Egikyan L. D. Vliyanie vremeni otmeny dvoinoi dezagregantnoi terapii v predoperatsionnom periode na chastotu resternotomii posle aortokoronarnogo shuntirovaniya. Klinicheskaja i jeksperimental’naja khirurgija. Zhurnal imeni akademika B. V. Petrovskogo. 2018;1:34–38. (In Russ.).2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation : Task Force for the Management of Acute Coronary Syndromes in Patients Presenting without Persistent ST-Segment Elevation of the European Society of Cardiology (ESC) // European Heart Journal. 2016. Vol. 37, № 3. P. 41.2015 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation: Task Force for the Management of Acute Coronary Syndromes in Patients Presenting without Persistent ST-Segment Elevation of the European Society of Cardiology (ESC). European Heart Journal. 2016;37(3):41.2017 ESC Guidelines for the management of acute coronary syndromes in patients presenting with ST-segment elevation : Task Force for the Management of Acute Coronary Syndromes in Patients Presenting with ST-Segment Elevation of the European Society of Cardiology (ESC) // European Heart Journal 2018. Volume 39, № 2. P. 119–177.2017 ESC Guidelines for the management of acute coronary syndromes in patients presenting with ST-segment elevation: Task Force for the Management of Acute Coronary Syndromes in Patients Presenting with ST-Segment Elevation of the European Society of Cardiology (ESC). European Heart Journal. 2018;39(2):119–177.Шихвердиев Н. Н. Трактат о врачебных ошибках. СПб. : Аликонт, 2017. 240 с.Shikhverdiev N. N. Traktat o vrachebnykh oshibkakh. Saint-Petersburg, Alikont, 2017:240. (In Russ.).

The authors declare that there are no conflicts of interest present.