grekovВестник хирургии имени И.И. ГрековаGrekov's Bulletin of Surgery0042-46252686-7370Federal State Budgetary Educational Institution of Higher Education «Academician I.P. Pavlov First St. Petersburg State Medical University» of the Ministry of Healthcare of the Russion Federation, FSBEI HE I.P.Pavlov SPbSMU MOH Russia10.24884/0042-4625-2020-179-3-113-119grekov-1441Research ArticleОБЗОРЫREVIEWSРадионавигационные и фотодинамические методики интраоперационной визуализации околощитовидных желез (обзор литературы)Radio navigation and photodynamic methods for intraoperative visualization of the parathyroid glands (review of literature)https://orcid.org/0000-0001-8918-1730РомащенкоП. Н.RomashchenkoP. N.

Ромащенко Павел Николаевич, доктор медицинских наук, профессор, член-корреспондент РАН, начальник кафедры факультетской хирургии им. С. П. Фёдорова

SPIN-код: 3850-1792

Санкт-Петербург

Romashchenko Pavel N., Dr. of Sci. (Med.), Professor, Head of the Department of Faculty Surgery named after S.P. Fedorov

Saint Petersburg

romashchenko@rambler.ruhttps://orcid.org/0000-0002-1405-7660МайстренкоН. А.MaistrenkoN. A.

Майстренко Николай Анатольевич, доктор медицинских наук, профессор, академик РАН, профессор кафедры факультетской хирургии им. С. П. Фёдорова

SPIN-код: 2571-9603

Санкт-Петербург

Maistrenko Nikolay A., Dr. of Sci. (Med.), Professor, Academician of the Russian Academy of Sciences,Pprofessor of the Department of Faculty Surgery named after S.P. Fedorov

Saint Petersburg

nik.m.47@mail.ruhttps://orcid.org/0000-0002-9499-2164КриволаповД. С.KrivolapovD. S.

Криволапов Денис Сергеевич, старший ординатор онкологического отделения кафедры факультетской хирургии им. С. П. Фёдорова

SPIN-код: 2195-5001

Санкт-Петербург

Krivolapov Denis S., Senior Resident of the Oncology Division of the Department of Faculty Surgery named after S.P. Fedorov

Saint Petersburg

d.s.krivolapov@yandex.ruhttps://orcid.org/0000-0002-9000-427XВшивцевД. О.VshivtsevD. O.

Вшивцев Дмитрий Олегович, клинический ординатор кафедры факультетской хирургии им. С. П. Фёдорова

SPIN-код: 9087-2432

194044, Санкт-Петербург, ул. Академика Лебедева, д. 6.

Vshivtsev Dmitriy O., Clinical Resident of the Department of Faculty Surgery named after S.P. Fedorov

6, Academika Lebedeva str., Saint Peter-sburg, 194044, Russia.

dvo_vsh@mail.ruФедеральное государственное бюджетное военное образовательное учреждение высшего образования «Военно-медицинская академия имени С. М. Кирова» Министерства обороны Российской ФедерацииРоссияMilitary Medical AcademyRussian Federation2020170520201793113119Copyright © Ромащенко П.Н., Майстренко Н.А., Криволапов Д.С., Вшивцев Д.О., 20202020Ромащенко П.Н., Майстренко Н.А., Криволапов Д.С., Вшивцев Д.О.Romashchenko P.N., Maistrenko N.A., Krivolapov D.S., Vshivtsev D.O.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.vestnik-grekova.ru/jour/article/view/1441

Интраоперационная идентификация здоровых околощитовидных желез и паратиром способствует благоприятному исходу хирургического лечения пациентов с заболеваниями щитовидной железы и различными формами гиперпаратиреоза. В связи с этим на сегодняшний день в эндокринную хирургию активно внедряются вспомогательные навигационные и визуализирующие методики, основанные на применении радиофармпрепаратов и флуоресцентных агентов, тропных к паратиреоидной ткани. В статье представлена сравнительная характеристика современных методик интраоперационной визуализации околощитовидных желез, основанная на данных мировой литературы.

Intraoperative identification of healthy parathyroid and parathyroid adenomas facilitate a favorable outcome of surgical treatment of patients with parathyroid diseases and various hyperparathyroidism’s forms. In doing so, it is important to preserve the entire parathyroid tissue, since unintentional damaging, removal or devascularization leads to the most common development of complication – hypoparathyroidism, which occasionally becomes permanent. Although, in case of surgical treatment of patients with hyperparathyroidism, the removal of the whole pathologically altered tissue is needed in order to avoid the persistence and recurrence hyperparathyroidism, as confirmed by intraoperative and postoperative parathyroid hormone examination. Up to recent time, surgeons could had relied only on pre-surgical localization of hyperfunctioning parathyroid glands, thorough knowledge of front neck anatomy and personal experience, which wasn’t always reliable to recognize the parathyroids intraoperatively and differentiate the healthy parathyroid tissue from adenoma. To solve these problems, the auxiliary navigation and visualization methods, based on application of radiopharmaceutical and fluorescent agents, tropic to parathyroid tissue, are being actively implemented to endocrine surgery nowadays. The comparative characteristic of modern methods for intraoperative visualization of the parathyroid glands, based on the worldwide literature data, is represented in this article.

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The authors declare that there are no conflicts of interest present.