<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">grekov</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник хирургии имени И.И. Грекова</journal-title><trans-title-group xml:lang="en"><trans-title>Grekov's Bulletin of Surgery</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0042-4625</issn><issn pub-type="epub">2686-7370</issn><publisher><publisher-name>Federal State Budgetary Educational Institution of Higher Education «Academician I.P. Pavlov First St. Petersburg State Medical University» of the Ministry of Healthcare of the Russion Federation, FSBEI HE I.P.Pavlov SPbSMU MOH Russia</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24884/0042-4625-2022-181-2-92-99</article-id><article-id custom-type="elpub" pub-id-type="custom">grekov-1926</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Осложнения в хирургии опухолей позвоночника (обзор литературы)</article-title><trans-title-group xml:lang="en"><trans-title>Complications in spinal tumor surgery (review of literature)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4562-8160</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Заборовский</surname><given-names>Н. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Zaborovskii</surname><given-names>N. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Заборовский Никита Сергеевич - кандидат медицинских наук, младший научный сотрудник отделения нейроортопедии и костной онкологии; ассистент кафедры общей хирургии</p><p>195427, Санкт-Петербург, ул. Академика Байкова, д. 8</p></bio><bio xml:lang="en"><p>Zaborovskii Nikita S. - Cand. of Sci. (Med.), Junior Research Fellow of the Department of Neuro-Orthopedics and Bone Oncology; Assistant of the Department of General Surgery</p><p>8, Akademika Baykova str., Saint Petersburg, 195427</p></bio><email xlink:type="simple">n.zaborovskii@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5765-3158</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пташников</surname><given-names>Д. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Ptashnikov</surname><given-names>D. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Пташников Дмитрий Александрович - доктор медицинских наук, профессор, руководитель отделения нейроортопедии и костной онкологии; зав. кафедрой ортопедии и травматологии с курсом ВПХ</p><p>195427, Санкт-Петербург, ул. Академика Байкова, д. 8</p></bio><bio xml:lang="en"><p>Ptashnikov Dmitry A. - Dr. of Sci. (Med.), Professor, Head of the Department of Neuro-Orthopedics and Bone Oncology; Head of the Department of Orthopedics and Traumatology with the Course of Military Field Surgery</p><p>8, Akademika Baykova str., Saint Petersburg, 195427</p></bio><email xlink:type="simple">drptashnikov@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4747-0806</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Михайлов</surname><given-names>Д. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Mikhailov</surname><given-names>D. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Михайлов Дмитрий Аркадьевич - кандидат медицинских наук, научный сотрудник отделения нейроортопедии и костной онкологии</p><p>195427, Санкт-Петербург, ул. Академика Байкова, д. 8</p></bio><bio xml:lang="en"><p>Mikhailov Dmitry A. - Cand. of Sci. (Med.), Research Fellow of the Department of Neuro-Orthopedics and Bone Oncology</p><p>8, Akademika Baykova str., Saint Petersburg, 195427</p></bio><email xlink:type="simple">dim.m.a@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4867-0332</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Смекалёнков</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Smekalenkov</surname><given-names>O. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Смекалёнков Олег Анатольевич - кандидат медицинских наук, младший научный сотрудник отделения нейроортопедии и костной онкологии</p><p>195427, Санкт-Петербург, ул. Академика Байкова, д. 8</p></bio><bio xml:lang="en"><p>Smekalenkov Oleg A. - Cand. of Sci. (Med.), Junior Research Fellow of the Department of Neuro-Orthopedics and Bone Oncology</p><p>8, Akademika Baykova str., Saint Petersburg, 195427</p></bio><email xlink:type="simple">drsmekalenkov@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9853-7089</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Масевнин</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Masevnin</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Масевнин Сергей Владимирович - кандидат медицинских наук, младший научный сотрудник отделения нейроортопедии и костной онкологии</p><p>195427, Санкт-Петербург, ул. Академика Байкова, д. 8</p></bio><bio xml:lang="en"><p>Masevnin Sergey V. - Cand. of Sci. (Med.), Junior Research Fellow of the Department of Neuro-Orthopedics and Bone Oncology</p><p>8, Akademika Baykova str., Saint Petersburg, 195427</p></bio><email xlink:type="simple">drmasevnin@gmail.com</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7196-6166</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дюсенов</surname><given-names>Д. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Diusenov</surname><given-names>D. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Дюсенов Даурен Оразбаевич - студент VI курса</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Diusenov Dauren O. - VI-year Student</p><p>Saint Petersburg</p></bio><email xlink:type="simple">dauren.dyusenov@inbox.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9412-6015</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Казанцев</surname><given-names>Н. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Kazantsev</surname><given-names>N. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Казанцев Никита Дмитриевич - студент VI курса</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Kazantsev Nikita D. - VI-year Student</p><p>Saint Petersburg</p></bio><email xlink:type="simple">nspartancev@bk.ru</email><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное учреждение «Национальный медицинский исследовательский центр травматологии и ортопедии имени Р. Р. Вредена» Министерства здравоохранения Российской Федерации; Федеральное государственное бюджетное образовательное учреждение высшего образования «Санкт-Петербургский государственный университет»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Scientific Research Institute of Traumatology and Orthopedics named after R. R. Vreden; Saint Petersburg University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное учреждение «Национальный медицинский исследовательский центр травматологии и ортопедии имени Р. Р. Вредена» Министерства здравоохранения Российской Федерации; Федеральное государственное бюджетное образовательное учреждение высшего образования «Северо-Западный государственный медицинский университет имени И. И. Мечникова» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Scientific Research Institute of Traumatology and Orthopedics named after R. R. Vreden; North-Western State Medical University named after I. I. Mechnikov</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное учреждение «Национальный медицинский исследовательский центр травматологии и ортопедии имени Р. Р. Вредена» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Russian Scientific Research Institute of Traumatology and Orthopedics named after R. R. Vreden</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное образовательное учреждение высшего образования «Первый Санкт-Петербургский государственный медицинский университет имени академика И. П. Павлова» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pavlov University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>14</day><month>04</month><year>2022</year></pub-date><volume>181</volume><issue>2</issue><fpage>92</fpage><lpage>99</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Заборовский Н.С., Пташников Д.А., Михайлов Д.А., Смекалёнков О.А., Масевнин С.В., Дюсенов Д.О., Казанцев Н.Д., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Заборовский Н.С., Пташников Д.А., Михайлов Д.А., Смекалёнков О.А., Масевнин С.В., Дюсенов Д.О., Казанцев Н.Д.</copyright-holder><copyright-holder xml:lang="en">Zaborovskii N.S., Ptashnikov D.A., Mikhailov D.A., Smekalenkov O.A., Masevnin S.V., Diusenov D.O., Kazantsev N.D.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.vestnik-grekova.ru/jour/article/view/1926">https://www.vestnik-grekova.ru/jour/article/view/1926</self-uri><abstract><p>Хирургия опухолей позвоночника часто требует комбинированных передних и задних доступов и относится к высокоинвазивным оперативным вмешательствам. Имеют место также анатомические и физиологические особенности области хирургического вмешательства. Таким образом, данные критерии отражают действительность проблемы интраоперационных осложнений в ходе хирургического лечения опухолей позвоночника. Авторами проведен обзор научной литературы на предмет изучения частоты и характера осложнений при хирургических вмешательствах по поводу опухолей позвоночника. Рассмотрены наиболее значимые факторы риска возникновения интраоперационных осложнений, основными из которых являются близость расположения магистральных сосудов и внутренних органов, развитие послеоперационной ликвореи, а также инфекции в области хирургического вмешательства. На основе изученной информации приведены меры профилактики и варианты хирургической тактики при возникновении осложнений.</p></abstract><trans-abstract xml:lang="en"><p>Combined anterior and posterior approaches are required in spinal tumor surgery and considered highly invasive. Anatomical and physiological features of the surgical intervention area should be taken into consideration as well. Thus, these criteria reflect the severity of intraoperative complications during the surgical treatment of spinal tumors. The authors reviewed the scientific literature on the frequency and nature of complications in surgical interventions for spinal tumors.The most significant risk factors for intraoperative complications have been considered, the main of which are: the proximity of the location of the main vessels and viscera, the development of postoperative liquorrhea, as well as surgical site infection. Based on the studied information, we presented the methods of prevention and surgical tactics options in complications.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>опухоли позвоночника</kwd><kwd>хирургическое лечение</kwd><kwd>интраоперационные осложнения</kwd><kwd>повреждения внутренних органов</kwd><kwd>послеоперационные осложнения</kwd></kwd-group><kwd-group xml:lang="en"><kwd>spinal tumors</kwd><kwd>surgical treatment</kwd><kwd>intraoperative complications</kwd><kwd>damage to internal organs</kwd><kwd>postoperative complications</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Dindo D., Demartines N., Clavien P. A. Classification of surgical complications : a new proposal with evaluation in a cohort of 6336 patients and results of a survey // Ann Surgю 2004. Vol. 240. P. 205–213. Doi: 10.1097/01.sla.0000133083.54934.ae.</mixed-citation><mixed-citation xml:lang="en">Dindo D., Demartines N., Clavien P. A. Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey // Ann Surg. 2004; (240):205–213. Doi: 10.1097/01. sla.0000133083.54934.ae.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Luksanapruksa P., Buchowski J. M., Zebala L. P. et al. Perioperative Complications of Spinal Metastases Surgery // Clinical Spine Surgery. 2017. Vol. 30. P. 4–13. Doi: 10.1097/BSD.0000000000000484.</mixed-citation><mixed-citation xml:lang="en">Luksanapruksa P., Buchowski J. M., Zebala L. P. et al. Perioperative Complications of Spinal Metastases Surgery // Clinical Spine Surgery. 2017;(30):4–13. Doi: 10.1097/BSD.0000000000000484.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Karhade A. V., Vasudeva V. S., Dasenbrock H. H. et al. Thirty-day readmission and reoperation after surgery for spinal tumors : a National Surgical Quality Improvement Program analysis // FOC. 2016. Vol. 41. P. E5. Doi: 10.3171/2016.5.FOCUS16168.</mixed-citation><mixed-citation xml:lang="en">Karhade A. V., Vasudeva V. S., Dasenbrock H. H. et al. Thirty-day readmission and reoperation after surgery for spinal tumors: a National Surgical Quality Improvement Program analysis // FOC. 2016;(41):E5. Doi: 10.3171/2016.5.FOCUS16168.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Paulino Pereira N. R., Ogink P. T., Groot O. Q. et al. Complications and reoperations after surgery for 647 patients with spine metastatic disease // The Spine Journal. 2019. Vol. 19. P. 144–156. Doi: 10.1016/j.spinee.2018.05.037.</mixed-citation><mixed-citation xml:lang="en">Paulino Pereira N. R., Ogink P. T., Groot O. Q. et al. Complications and reoperations after surgery for 647 patients with spine metastatic disease // The Spine Journal. 2019;(19):144–156. Doi: 10.1016/j.spinee.2018.05.037.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Alamanda V. K., Robinson M. M., Kneisl J. S. et al. Survival Outcomes and Factors Associated with Revision Surgery for Metastatic Disease of the Spine // Journal of Oncology. 2018. P. 1–6. Doi: 10.1155/2018/6140381.</mixed-citation><mixed-citation xml:lang="en">Alamanda V. K., Robinson M. M., Kneisl J. S. et al. Survival Outcomes and Factors Associated with Revision Surgery for Metastatic Disease of the Spine // Journal of Oncology. 2018:1–6. Doi: 10.1155/2018/6140381.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Boriani S., Bandiera S., Donthineni R. et al. Morbidity of en bloc resections in the spine // Eur. Spine J. 2010. Vol. 19. P. 231–241. Doi: 10.1007/s00586-009-1137-z.</mixed-citation><mixed-citation xml:lang="en">Boriani S., Bandiera S., Donthineni R. et al. Morbidity of en bloc resections in the spine // Eur. Spine J. 2010;(19):231–241. Doi: 10.1007/s00586-009-1137-z.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Boriani S., Gasbarrini A., Bandiera S. et al. Predictors for surgical complications of en bloc resections in the spine : review of 220 cases treated by the same team // Eur. Spine J. 2016. Vol. 25. P. 3932–3941. Doi: 10.1007/s00586-016-4463-y.</mixed-citation><mixed-citation xml:lang="en">Boriani S., Gasbarrini A., Bandiera S. et al. Predictors for surgical complications of en bloc resections in the spine: review of 220 cases treated by the same team // Eur. Spine J. 2016;(25):3932–3941. Doi: 10.1007/s00586-016-4463-y.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Yang S. B., Cho W., Chang U. K. Analysis of Prognostic Factors Relating to Postoperative Survival in Spinal Metastases // J. Korean Neurosurg. Soc. 2012. Vol. 51. P. 127–134. Doi: 10.3340/jkns.2012.51.3.127.</mixed-citation><mixed-citation xml:lang="en">Yang S. B., Cho W., Chang U. K. Analysis of Prognostic Factors Relating to Postoperative Survival in Spinal Metastases // J. Korean Neurosurg. Soc. 2012;(51):127–134. Doi: 10.3340/jkns.2012.51.3.127.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Amendola L., Cappuccio M., De F. I. et al. En bloc resections for primary spinal tumors in 20 years of experience : effectiveness and safety // Spine J. 2014. Vol. 14. P. 2608–2617. Doi: 10.1016/j.spinee.2014.02.030</mixed-citation><mixed-citation xml:lang="en">Amendola L., Cappuccio M., De F. I. et al. En bloc resections for primary spinal tumors in 20 years of experience: effectiveness and safety // Spine J. 2014;(14):2608–2617. Doi: 10.1016/j.spinee.2014.02.030.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Varga P., Szövérfi Z., Lazáry A. Surgical treatment of primary malignant tumors of the sacrum // Neurological research. 2014. Vol. 36. P. 1743132814Y0000000366. Doi: 10.1179/1743132814Y.0000000366</mixed-citation><mixed-citation xml:lang="en">Varga P., Szövérfi Z., Lazáry A. Surgical treatment of primary malignant tumors of the sacrum // Neurological research. 2014;(36):1743132814 Y0000000366. Doi: 10.1179/1743132814Y.0000000366.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Boriani S., Gasbarrini A., Bandiera S. et al. En Bloc Resections in the Spine : The Experience of 220 Patients During 25 Years // World Neurosurgery. 2017. Vol. 98. P. 217–229. Doi: 10.1016/j.wneu.2016.10.086.</mixed-citation><mixed-citation xml:lang="en">Boriani S., Gasbarrini A., Bandiera S. et al. En Bloc Resections in the Spine: The Experience of 220 Patients During 25 Years // World Neurosurgery. 2017;(98):217–229. Doi: 10.1016/j.wneu.2016.10.086.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Усиков В. Д., Пташников Д. А., Магомедов Ш. Ш. Корпор- и спондилэктомия в системе хирургического лечения опухолей позвоночника // Травматология и ортопедия России. 2010. C. 140–142.</mixed-citation><mixed-citation xml:lang="en">Usikov V. D., Ptashnikov D. A., Magomedov Sh. Sh. corpor-and spondylectomy in system of surgical treatmentof vertebral tumors // Traumatology and Orthopedics of Russia. 2010;140–142. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Возмещение кровопотери при корпор- и спондилоэктомии у больных с опухолями позвоночника / Ю. Н. Мыльников, В. Д. Усиков, Д. A. Пташников, Ш. Ш. Магомедов // Травматология и ортопедия России. 2008. C. 102–110.</mixed-citation><mixed-citation xml:lang="en">Myl’nikov Yu. N., Usikov V. D., Ptashnikov D. A., Magomedov Sh. Sh. Compensation for blood loss during vertebral body resection and spondylectomy in patients with spinal tumors // Traumatology and Orthopedics of Russia. 2008;102–110. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Preoperative embolization versus local hemostatic agents in surgery of hypervascular spinal tumors / D. Ptashnikov, N. Zaborovskii, D. Mikhaylov, S. Masevnin // Int. J. Spine Surg. 2014. P. 8. Doi: 10.14444/1033.</mixed-citation><mixed-citation xml:lang="en">Ptashnikov D., Zaborovskii N., Mikhaylov D., Masevnin S. Preoperative embolization versus local hemostatic agents in surgery of hypervascular spinal tumors // Int J Spine Surg. 2014;8. Doi: 10.14444/1033.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Zaborovskii N., Ptashnikov D., Mikaylov D. et al. Preoperative embolization and local hemostatic agents in palliative decompression surgery for spinal metastases of renal cell carcinoma // Eur. J. Orthop. Surg. Traumatol. 2018. Vol. 28. P. 1047–1052. Doi: 10.1007/s00590-018-2162-6.</mixed-citation><mixed-citation xml:lang="en">Zaborovskii N., Ptashnikov D., Mikaylov D. et al. Preoperative embolization and local hemostatic agents in palliative decompression surgery for spinal metastases of renal cell carcinoma // Eur J Orthop Surg Traumatol. 2018;(28):1047–1052. Doi: 10.1007/s00590-018-2162-6.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Zaborovskii N., Ptashnikov D., Mikaylov D. et al. Renal cell carcinoma metastasis of the spine – bleeding control methods // Coluna/Columna. 2018. Vol. 17. P. 233–236. Doi: 10.1590/s1808-185120181703193262.</mixed-citation><mixed-citation xml:lang="en">Zaborovskii N., Ptashnikov D., Mikaylov D. et al. Renal cell carcinoma metastasis of the spine – bleeding control methods // Coluna/Columna. 2018;(17):233–236. Doi: 10.1590/s1808-185120181703193262.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Kato S., Hozumi T., Takaki Y. et al. Optimal Schedule of Preoperative Embolization for Spinal Metastasis Surgery // Spine. 2013. Vol. 38. P. 1964–1969. Doi: 10.1097/BRS.0b013e3182a46576.</mixed-citation><mixed-citation xml:lang="en">Kato S., Hozumi T., Takaki Y. et al. Optimal Schedule of Preoperative Embolization for Spinal Metastasis Surgery // Spine. 2013;(38):1964–1969. Doi: 10.1097/BRS.0b013e3182a46576.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Zanirato A., Damilano M., Formica M. et al. Complications in adult spine deformity surgery : a systematic review of the recent literature with reporting of aggregated incidences // Eur. Spine J 2018. Vol. 27. P. 2272–2284. Doi: 10.1007/s00586-018-5535-y.</mixed-citation><mixed-citation xml:lang="en">Zanirato A., Damilano M., Formica M. et al. Complications in adult spine deformity surgery: a systematic review of the recent literature with reporting of aggregated incidences // Eur Spine J. 2018;(27):2272–2284. Doi: 10.1007/s00586-018-5535-y.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Заборовский Н. С., Пташников Д. А., Топузов Э. Э. и др. Эпидемиология опухолей позвоночника у пациентов, получивших специализированную ортопедическую помощь // Травматология и ортопедия России. 2019. Т. 25. С. 104–112. Doi: 10.21823/2311-2905-2019-25-1-104-112.</mixed-citation><mixed-citation xml:lang="en">Zaborovskii N. S., Ptashnikov D. A., Topuzov E. E. et al. Epidemiologiya opuholej pozvonochnika u pacientov, poluchivshih specializirovannuyu ortopedicheskuyu pomoshch’ // Traumatology and Orthopedics of Russia. 2019;(25):104–112. (In Russ.). Doi: 10.21823/2311-2905-2019-25-1-104-112.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Papavero L., Engler N., Kothe R. Incidental durotomy in spine surgery : first aid in ten steps // Eur. Spine J. 2015. Vol. 24. P. 2077–2084. Doi: 10.1007/s00586-015-3837-x.</mixed-citation><mixed-citation xml:lang="en">Papavero L., Engler N., Kothe R. Incidental durotomy in spine surgery: first aid in ten steps // Eur Spine J. 2015;(24):2077–2084. Doi: 10.1007/ s00586-015-3837-x.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Hentschel S. J., Rhines L. D., Wong F. C. et al. Subarachnoid-pleural fistula after resection of thoracic tumors // J. Neurosurg. 2004. Vol. 100. P. 332–336. Doi: 10.3171/spi.2004.100.4.0332.</mixed-citation><mixed-citation xml:lang="en">Hentschel S. J., Rhines L. D., Wong F. C. et al. Subarachnoid-pleural fistula after resection of thoracic tumors // J Neurosurg. 2004;(100):332–336. Doi: 10.3171/spi.2004.100.4.0332.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Heller J. G., Sun Kim H, W. Carlson G. Subarachnoid–Pleural Fistulae–Management With a Transdiaphragmatic Pedicled Greater Omental Flap : Report of Two Cases // Spine. 2001. Vol. 26. P. 1809–1813.</mixed-citation><mixed-citation xml:lang="en">Heller J. G., Sun Kim H. W. Carlson G. Subarachnoid–Pleural Fistulae—Management With a Transdiaphragmatic Pedicled Greater Omental Flap: Report of Two Cases // Spine. 2001;(26):1809–1813.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Stendel R., Danne M., Fiss I. et al. Efficacy and safety of a collagen matrix for cranial and spinal dural reconstruction using different fixation techniques // Journal of Neurosurgery. 2008. Vol. 109. P. 215–221. Doi: 10.3171/JNS/2008/109/8/0215.</mixed-citation><mixed-citation xml:lang="en">Stendel R., Danne M., Fiss I. et al. Efficacy and safety of a collagen matrix for cranial and spinal dural reconstruction using different fixation techniques // Journal of Neurosurgery. 2008;(109):215–221. Doi: 10.3171/JNS/2008/109/8/0215.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Sciubba D. M., Ramos R. D la G., Goodwin C. R. et al. Clinical, surgical, and molecular prognostic factors for survival after spinal sarcoma resection // Neurosurgical Focus. 2016. Vol. 41. P. E9. Doi: 10. 3171/2016.5.FOCUS16118.</mixed-citation><mixed-citation xml:lang="en">Sciubba D. M., Ramos R. D. la G., Goodwin C. R. et al. Clinical, surgical, and molecular prognostic factors for survival after spinal sarcoma resection // Neurosurgical Focus. 2016; (41):E9. Doi: 10.3171/2016.5.FOCUS16118.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Fisher C. G., Saravanja D. D., Dvorak M. F. et al. Surgical Management of Primary Bone Tumors of the Spine : Validation of an Approach to Enhance Cure and Reduce Local Recurrence // Spine. 2011. Vol. 36. P. 830–836. Doi: 10.1097/BRS.0b013e3181e502e5.</mixed-citation><mixed-citation xml:lang="en">Fisher C. G., Saravanja D. D., Dvorak M. F. et al. Surgical Management of Primary Bone Tumors of the Spine: Validation of an Approach to Enhance Cure and Reduce Local Recurrence // Spine. 2011;(36):830–836. Doi: 10.1097/BRS.0b013e3181e502e5.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Заборовский Н. С., Пташников Д. А., Михайлов Д. А. и др. Результаты оперативного лечения 845 больных с метастатическим поражением позвоночника // Актуальные проблемы травматологии и ортопедии : сб. науч. ст., посвящ. 110-летию РНИИТО им. Р. Р. Вредена. 2016. C. 69–74.</mixed-citation><mixed-citation xml:lang="en">Zaborovskii N. S., Ptashnikov D. A., Mihajlov D. A. et al. Results of surgical treatment of 845 patients with metastatic lesions of the spine. Actual problems of traumatology and orthopedics, a collection of scientific articles dedicated to the 110th anniversary of the RNIITO them. R. R. Vredena. 2016:69–74. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Bouras T., Zairi F., Arikat A. et al. Decision Making for the Surgical Treatment of Vertebral Metastases Among Patients with Short Predicted Survival // World Neurosurgery. 2018. Vol. 111. P. e573–e580. Doi: 10.1016/j.wneu.2017.12.107.</mixed-citation><mixed-citation xml:lang="en">Bouras T., Zairi F., Arikat A. et al. Decision Making for the Surgical Treatment of Vertebral Metastases Among Patients with Short Predicted Survival // World Neurosurgery. 2018;(111):e573–e580. Doi: 10.1016/j.wneu.2017.12.107.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">The outcome and survival of palliative surgery in thoraco-lumbar spinal metastases : contemporary retrospective cohort study / R. M. Nemelc, A. Stadhouder, B. J. van Royen, T. U. Jiya // Eur Spine J. 2014. Vol. 23. P. 2272–2278. Doi: 10.1007/s00586-014-3268-0.</mixed-citation><mixed-citation xml:lang="en">Nemelc R. M., Stadhouder A., van Royen B. J., Jiya T. U. The outcome and survival of palliative surgery in thoraco-lumbar spinal metastases: contemporary retrospective cohort study // Eur Spine J. 2014;(23):2272–2278. Doi: 10.1007/s00586-014-3268-0.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Risk Factors for Surgical Site Infection After Spinal Surgery : A Systematic Review and Meta-Analysis Based on Twenty-Seven Studies / X. Q. Peng, C. G. Sun, Z. G. Fei, Q. J. Zhou // World Neurosurgery. 2019. Vol. 123. P. e318–e329. Doi: 10.1016/j.wneu.2018.11.158.</mixed-citation><mixed-citation xml:lang="en">Peng X. Q., Sun C. G., Fei Z. G., Zhou Q. J. Risk Factors for Surgical Site Infection After Spinal Surgery: A Systematic Review and Meta-Analysis Based on Twenty-Seven Studies // World Neurosurgery. 2019;(123):e318–e329. Doi: 10.1016/j.wneu.2018.11.158.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Deng H., Chan A. K., Ammanuel S. G. et al. Risk factors for deep surgical site infection following thoracolumbar spinal surgery // Journal of Neurosurgery : Spine. 2019. Vol. 32. P. 292–301. Doi: 10.3171/2019.8.SPINE19479.</mixed-citation><mixed-citation xml:lang="en">Deng H., Chan A. K., Ammanuel S. G. et al. Risk factors for deep surgical site infection following thoracolumbar spinal surgery // Journal of Neurosurgery: Spine. 2019;(32):292–301. Doi: 10.3171/2019.8.SPINE19479.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Смекаленков О. А., Пташников Д. А., Божкова С. А. и др. Факторы риска развития глубокой инфекции области хирургического вмешательства после операций на позвоночнике // Гений ортопедии. 2019. Т. 25. С. 219–225. Doi: 10.18019/1028-4427-2019-25-2-219-225.</mixed-citation><mixed-citation xml:lang="en">Smekalyonkov O. A., Ptashnikov D. A., Bozhkova S. A. et al. Risk factors for deep infection in the surgical site after spinal operations // Genij Ortopedii. 2019;(25):219–225. (In Russ.). Doi: 10.18019/1028-4427-2019-25-2-219-225.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Смекаленков О. А., Пташников Д. А., Заборовский Н. С. и др. Факторы риска развития инфекционных осложнений после хирургического лечения спинальных метастазов у пациентов с раком молочных желез и почек // Травматология и ортопедия России. 2019. Т. 25. С. 126–133. Doi: 10.21823/2311-2905-2019-25-4-126-133.</mixed-citation><mixed-citation xml:lang="en">Smekalyonkov O. A., Ptashnikov D. A., Zaborovskii N. S. et al. Risk Factors for Infectious Complications after Surgical Treatment of Spinal Metastases in Patients with Breast and Kidney Cancer // Traumatology and Orthopedics of Russia. 2019;(25):126–133. (In Russ.). Doi: 10.21823/2311-2905-2019-25-4-126-13333.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Revision surgery for tumors of the thoracic and lumbar spine : causes, prevention, and treatment strategy / P. Berjano, R. Cecchinato, A. Pun, S. Boriani // Eur. Spine J. 2020. Vol. 29. P. 66–77. Doi: 10.1007/s00586-019-06276-8.</mixed-citation><mixed-citation xml:lang="en">Berjano P., Cecchinato R., Pun A., Boriani S. Revision surgery for tumors of the thoracic and lumbar spine: causes, prevention, and treatment strategy // Eur Spine J. 2020;(29):66–77. Doi: 10.1007/s00586-019-06276-8.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Haynes A. B. Weiser T. G. Berry W. R. et al. A Surgical Safety Checklist to Reduce Morbidity and Mortality in a Global Population // New England Journal of Medicine. 2009. Vol. 360. P. 491–499. Doi: 10.1056/NEJMsa0810119.</mixed-citation><mixed-citation xml:lang="en">Haynes A. B., Weiser T. G., Berry W. R. et al. A Surgical Safety Checklist to Reduce Morbidity and Mortality in a Global Population. New England Journal of Medicine. 2009;(360):491–499. Doi: 10.1056/NEJMsa0810119.</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Mesfin A., Sciubba D. M., Dea N. et al. Changing the Adverse Event Profile in Metastatic Spine Surgery : An Evidence-Based Approach to Target Wound Complications and Instrumentation Failure // Spine. 2016. Vol. 41. P. S262–S270. Doi: 10.1097/BRS.0000000000001817.</mixed-citation><mixed-citation xml:lang="en">Mesfin A., Sciubba D. M., Dea N. et al. Changing the Adverse Event Profile in Metastatic Spine Surgery: An Evidence-Based Approach to Target Wound Complications and Instrumentation Failure // Spine. 2016;(41):S262–S270. Doi: 10.1097/BRS.0000000000001817.</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Thromboembolic Disease in Spinal Surgery : A Systematic Review / M. P. Glotzbecker, C. M. Bono, K. B. Wood, M. B. Harris // Spine. 2009. Vol. 34. P. 291–303. Doi: 10.1097/BRS.0b013e318195601d.</mixed-citation><mixed-citation xml:lang="en">Glotzbecker M. P., Bono C. M., Wood K. B., Harris M. B. Thromboembolic Disease in Spinal Surgery: A Systematic Review // Spine. 2009;(34):291–303. Doi: 10.1097/BRS.0b013e318195601d.</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Piper K., Algattas H., DeAndrea-Lazarus I. A. et al. Risk factors associated with venous thromboembolism in patients undergoing spine surgery // Journal of Neurosurgery : Spine. 2017. Vol. 26. P. 90–96. Doi: 10.3171/2016.6.SPINE1656.</mixed-citation><mixed-citation xml:lang="en">Piper K., Algattas H., DeAndrea-Lazarus I. A. et al. Risk factors associated with venous thromboembolism in patients undergoing spine surgery // Journal of Neurosurgery: Spine. 2017;(26):90–96. Doi: 10.3171/2016.6.SPINE1656.</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Harmanci A., Harmanci O., Akova M. Hospital-acquired pneumonia : challenges and options for diagnosis and treatment // J. Hosp Infect. 2002. Vol. 51. P. 160–167. Doi: 10.1053/jhin.2002.1230.</mixed-citation><mixed-citation xml:lang="en">Harmanci A., Harmanci O., Akova M. Hospital-acquired pneumonia: challenges and options for diagnosis and treatment // J Hosp Infect. 2002;(51):160–167. Doi: 10.1053/jhin.2002.1230.</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Nagele P., Liggett S. B. Genetic Variation, β-Blockers, and Perioperative Myocardial Infarction // Anesthesiology. 2011. Vol. 115. P. 1316–1327. Doi: 10.1097/ALN.0b013e3182315eb2.</mixed-citation><mixed-citation xml:lang="en">Nagele P., Liggett S. B. Genetic Variation, β-Blockers, and Perioperative Myocardial Infarction // Anesthesiology. 2011;(115):1316–1327. Doi: 10. 1097/ALN.0b013e3182315eb2.</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Atlee J. L. Perioperative Cardiac Dysrhythmias Diagnosis and Management // Anesthesiology. 1997. Vol. 86. P. 1397–1424.</mixed-citation><mixed-citation xml:lang="en">Atlee J. L. Perioperative Cardiac Dysrhythmias Diagnosis and Management // Anesthesiology. 1997;(86):1397–1424.</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Incidence and Risk Factors for Gastrointestinal Hemorrhage After Lumbar Fusion / S. J. Fineberg, M. F. Kurd, A. A. Patel, K. Singh // Spine. 2013. Vol. 38. P. 1584–1589. Doi: 10.1097/BRS.0b013e318298768d.</mixed-citation><mixed-citation xml:lang="en">Fineberg S. J., Kurd M. F., Patel A. A., Singh K. Incidence and Risk Factors for Gastrointestinal Hemorrhage After Lumbar Fusion // Spine. 2013;(38):1584–1589. Doi: 10.1097/BRS.0b013e318298768d.</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Batke M., Cappell M. S. Adynamic ileus and acute colonic pseudoobstruction // Med. Clin. North Am. 2008. Vol. 92. P. 649–670. Doi: 10. 1016/j.mcna.2008.01.002.</mixed-citation><mixed-citation xml:lang="en">Batke M., Cappell M. S. Adynamic ileus and acute colonic pseudoobstruction // Med Clin North Am. 2008;(92):649–670. Doi: 10.1016/j.mcna.2008.01.002.</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Relationship between the duration of the preoperative smoke-free period and the incidence of postoperative pulmonary complications after pulmonary surgery / M. Nakagawa, H. Tanaka, H. Tsukuma, Y. Kishi // Chest. 2001. Vol. 120. P. 705–710. Doi: 10.1378/chest.120.3.705.</mixed-citation><mixed-citation xml:lang="en">Nakagawa M., Tanaka H., Tsukuma H., Kishi Y. Relationship between the duration of the preoperative smoke-free period and the incidence of postoperative pulmonary complications after pulmonary surgery // Chest. 2001;(120):705–710. Doi: 10.1378/chest.120.3.705.</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Заборовский Н. С. Влияние предоперационной эмболизации и местных гемостатических средств на результаты полного хирургического удаления метастазов из позвоночника при комплексном лечении пациентов с почечно-клеточной карциномой // Актуальные проблемы травматологии и ортопедии : сб. науч. ст., посвящ. 110-летию РНИИТО им. Р. Р. Вредена. 2016. С. 64–69</mixed-citation><mixed-citation xml:lang="en">Zaborovskii N. S. Influence of preoperative embolization and local hemostatic agents on the results of complete surgical removal of metastases from the spine in the complex treatment of patients with renal cell carcinoma. Actual problems of traumatology and orthopedics, a collection of scientific articles dedicated to the 110th anniversary of the RNIITO them. R. R. Vredena. 2016;64–69. (In Russ.).</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">Профилактика кровопотери при резекции гиперваскуляризированных опухолей позвоночника с использованием предоперационной эмболизации и местных гемостатических средств / Н. С. Заборовский, Д. А. Пташников, Д. А. Михайлов, С. В. Масевнин // Вопросы онкологии. 2016. Т. 62. С. 639–642.</mixed-citation><mixed-citation xml:lang="en">Zaborovskii N. S., Ptashnikov D. A., Mihajlov D. A., Masevnin S. V. Prevention of blood loss during resection of hypervascular spinal tumors with the use of preoperative embolization and local hemostatic agents // Problems in Oncology. 2016;(62):639–642. (In Russ.).</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
