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<article article-type="review-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">grekov</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник хирургии имени И.И. Грекова</journal-title><trans-title-group xml:lang="en"><trans-title>Grekov's Bulletin of Surgery</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0042-4625</issn><publisher><publisher-name>Federal State Budgetary Educational Institution of Higher Education «Academician I.P. Pavlov First St. Petersburg State Medical University» of the Ministry of Healthcare of the Russion Federation, FSBEI HE I.P.Pavlov SPbSMU MOH Russia</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24884/0042-4625-2022-181-6-98-104</article-id><article-id custom-type="elpub" pub-id-type="custom">grekov-2095</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Стратификация рисков несостоятельности анастомозов после резекционных и реконструктивно-восстановительных операций на толстой кишке</article-title><trans-title-group xml:lang="en"><trans-title>Risk stratification of anastomotic leakages after colonic resection and reconstructive procedures</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0815-7032</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ваганов</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Vaganov</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ваганов Алексей Александрович, кандидат медицинских наук, ассистент кафедры хирургии общей с клиникой</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Vaganov Aleksey A., Cand. of Sci. (Med.), Assistant of the Department of General Surgery with Clinic</p><p>Saint Petersburg</p></bio><email xlink:type="simple">wellex07@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7449-6908</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Корольков</surname><given-names>А. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Korol’kov</surname><given-names>A. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Корольков Андрей Юрьевич, доктор медицинских наук, профессор кафедры хирургии общей с клиникой, руководитель отдела неотложной хирургии НИИ хирургии и неотложной медицины</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Korol’kov Andrey Yu., Dr. of Sci. (Med.), Professor of the Department of General Surgery with Clinic, Head of the Department of the Research Institute of Surgery and Emergency Medicine</p><p>Saint Petersburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7824-7036</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Богданов</surname><given-names>П. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Bogdanov</surname><given-names>P. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Богданов Петр Иванович, кандидат медицинских наук, доцент кафедры хирургии общей с клиникой, заведующий хирургическим отделением № 3 НИИ хирургии и неотложной медицины</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Bogdanov Petr I., Cand. of Sci. (Med.), Associate Professor of the Department of General Surgery with Clinic, Head of the Surgical Department № 3 of the Research Institute of Surgery and Emergency Medicine</p><p>Saint Petersburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9671-0394</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Османов</surname><given-names>З. Х.</given-names></name><name name-style="western" xml:lang="en"><surname>Osmanov</surname><given-names>Z. Kh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Османов Зейнур Худдусович, кандидат медицинских наук, доцент кафедры хирургии общей с клиникой</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Osmanov Zeinur Kh., Cand. of Sci. (Med.), Associate Professor of the Department of General Surgery with Clinic</p><p>Saint Petersburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7395-7020</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Морозов</surname><given-names>В. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Morozov</surname><given-names>V. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Морозов Виктор Петрович, доктор медицинских наук, профессор, зав. кафедрой хирургии общей с клиникой</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Morozov Victor P., Dr. of Sci. (Med.), Professor, Head of the Department of General Surgery with Clinic</p><p>Saint Petersburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6269-6283</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бабич</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Babich</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бабич Андрей Валентинович, клинический ординатор кафедры хирургии общей с клиникой</p><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>Babich Andrey V., Postgraduate Student of the Department of General Surgery with Clinic</p><p>Saint Petersburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Федеральное государственное бюджетное образовательное учреждение высшего образования «Первый Санкт-Петербургский государственный медицинский университет имени академика И. П. Павлова» Министерства здравоохранения Российской Федерации</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pavlov University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>03</day><month>02</month><year>2023</year></pub-date><volume>181</volume><issue>6</issue><fpage>98</fpage><lpage>104</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ваганов А.А., Корольков А.Ю., Богданов П.И., Османов З.Х., Морозов В.П., Бабич А.В., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Ваганов А.А., Корольков А.Ю., Богданов П.И., Османов З.Х., Морозов В.П., Бабич А.В.</copyright-holder><copyright-holder xml:lang="en">Vaganov A.A., Korol’kov A.Y., Bogdanov P.I., Osmanov Z.K., Morozov V.P., Babich A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.vestnik-grekova.ru/jour/article/view/2095">https://www.vestnik-grekova.ru/jour/article/view/2095</self-uri><abstract><p>ЦЕЛЬ. Проанализировать доступные за последние 5 лет исследования с последующей систематизацией основных групп факторов, приводящих к несостоятельности толстокишечных анастомозов после резекционных и реконструктивно-восстановительных операций.</p><p>Анализ литературы проведен в медицинских базах PubMed, Medline, Cochrane Library, Web of Science. Учитывая представленную большую выборку пациентов и количество оцениваемых факторов со статически значимой достоверностью, в литературный обзор вошли 22 рандомизированных исследования и метаанализа. Проанализированы и представлены контролируемые и неконтролируемые факторы, приводящие к несостоятельности толстокишечных анастомозов после реконструктивно-восстановительных и резекционных операций на разных этапах лечения данной категории пациентов. Частота развития несостоятельности межкишечных анастомозов, по данным изученной литературы, довольно высока. Оценка доказанных факторов и их нивелирование в дооперационном периоде позволит в большинстве случаев снизить риски и, как следствие, частоту несостоятельностей кишечных анастомозов, что значительно улучшит результаты лечения колопроктологических пациентов.</p></abstract><trans-abstract xml:lang="en"><p>The OBJECTIVE to analyze the available researches over the past 5 years and systematized the main groups of factors, which leading to the leakages of colonic anastomoses after resection and reconstructive procedures. Literature analysis was carried in the medical databases PubMed, Medline, Cochrane Library, Web of Science. 22 randomized trials and meta-analyses were included in the literature review. All researches investigated large sample of patients presented and the number of factors evaluated with statistically significant reliability. We analyzed and presented the controlled and uncontrolled factors, which were leading to leakages of colonic anastomoses after reconstructive and resection procedures at different stages of treatment of this category of patients. The frequency of the development of the leakages of interstitial anastomoses according to the studied literature is high. Evaluation of proven factors in the preoperative period will in most cases reduce the risks and, as a consequence, the frequency of leakages of colonic anastomoses. This will be significantly improved to the results of treatment of coloproctological patients. </p></trans-abstract><kwd-group xml:lang="ru"><kwd>колоректальная хирургия</kwd><kwd>реконструктивно-восстановительные операции</kwd><kwd>резекционные операции</kwd><kwd>несостоятельность анастомоза</kwd><kwd>факторы рисков</kwd></kwd-group><kwd-group xml:lang="en"><kwd>colorectal surgery</kwd><kwd>reconstructive procedures</kwd><kwd>resection operations</kwd><kwd>anastomosis leakages</kwd><kwd>risk factors</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Amanai E., Nakai J., Saito E. et al. Morohashi Usefulness of presepsin for the early detection of infectious complications after elective colorectal surgery, compared with C-reactive protein and procalcitonin // Sci Rep. 2022. Vol. 12, № 1. 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