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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">grekov</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник хирургии имени И.И. Грекова</journal-title><trans-title-group xml:lang="en"><trans-title>Grekov's Bulletin of Surgery</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0042-4625</issn><issn pub-type="epub">2686-7370</issn><publisher><publisher-name>Federal State Budgetary Educational Institution of Higher Education «Academician I.P. Pavlov First St. Petersburg State Medical University» of the Ministry of Healthcare of the Russion Federation, FSBEI HE I.P.Pavlov SPbSMU MOH Russia</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24884/0042-4625-2023-182-1-35-42</article-id><article-id custom-type="elpub" pub-id-type="custom">grekov-2171</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ХИРУРГИЯ ДЕТСКОГО ВОЗРАСТА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>SURGERY IN CHILDREN</subject></subj-group></article-categories><title-group><article-title>Миниинвазивный способ профилактики кровотечений из варикозных вен пищевода при внепеченочной портальной гипертензии у детей</article-title><trans-title-group xml:lang="en"><trans-title>Minimal invasive prophylaxis of bleeding from esophageal varices in children with extrahepatic portal hypertension</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4335-9879</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Юлдашев</surname><given-names>Р. З.</given-names></name><name name-style="western" xml:lang="en"><surname>Yuldashev</surname><given-names>R. Z.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Юлдашев Рустам Зафарджанович, кандидат медицинскиъх наук, докторант кафедры факультетской хирургии детского возраста, 100140, г. Ташкент, ул. Богишамол, д. 223;</p><p>детский хирург, отделение детской хирургии, г. Ташкент</p></bio><bio xml:lang="en"><p>Yuldashev Rustam Z., Cand. of Sci. (Med.), Postdoctoral Fellow, Department of Faculty Surgery of Childhood, 223, Bogishamol str., Tashkent, 100140;</p><p>Pediatric Surgeon, Department of Pediatric Surgery, Tashkent</p></bio><email xlink:type="simple">yuldashev.rustam@yahoo.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7229-3445</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алиев</surname><given-names>М. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Aliev</surname><given-names>M. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Алиев Махмуд Муслимович, доктор медицинских наук, профессор кафедры факультетской хирургии детского возраста, </p><p>100140, г. Ташкент, ул. Богишамол, д. 223</p></bio><bio xml:lang="en"><p>Aliev Mahmud M., Doct. of Sci. (Med), Professor of the Department of Pediatric Surgery, </p><p>Tashkent</p></bio><email xlink:type="simple">mahmudali47@list.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6842-1635</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шохайдаров</surname><given-names>Ш. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Shokhaidarov</surname><given-names>Sh. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шохайдаров Шоилхом, врач эндоскопист отделения детской хирургии, </p><p>г. Ташкент</p></bio><bio xml:lang="en"><p>Shokhaidarov Shoilkhom I., Endoscopist, Department of Pediatric Surgery, </p><p>223, Bogishamol str., Tashkent, 100140</p></bio><email xlink:type="simple">shoilhom@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Ташкентский педиатрический медицинский институт;&#13;
Республиканский специализированный научно-практический медицинский центр педиатрии</institution><country>Узбекистан</country></aff><aff xml:lang="en"><institution>Tashkent Pediatric Medical Institute;&#13;
Republican Specialized Scientific-Practical Medical Center of Pediatrics</institution><country>Uzbekistan</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Ташкентский педиатрический медицинский институт</institution><country>Узбекистан</country></aff><aff xml:lang="en"><institution>Tashkent Pediatric Medical Institute</institution><country>Uzbekistan</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Республиканский специализированный научно-практический медицинский центр педиатрии</institution><country>Узбекистан</country></aff><aff xml:lang="en"><institution>Republican Specialized Scientific-Practical Medical Center of Pediatrics</institution><country>Uzbekistan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>06</day><month>04</month><year>2023</year></pub-date><volume>182</volume><issue>1</issue><fpage>35</fpage><lpage>42</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Юлдашев Р.З., Алиев М.М., Шохайдаров Ш.И., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Юлдашев Р.З., Алиев М.М., Шохайдаров Ш.И.</copyright-holder><copyright-holder xml:lang="en">Yuldashev R.Z., Aliev M.M., Shokhaidarov S.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.vestnik-grekova.ru/jour/article/view/2171">https://www.vestnik-grekova.ru/jour/article/view/2171</self-uri><abstract><p>Целью исследования явилось изучение эффективности миниинвазивного эндоскопического лечения варикозных вен пищевода (ВРВП) у детей с внепеченочной портальной гипертензией (ВПГ).</p><sec><title>Методы и материалы</title><p>Методы и материалы. В исследование включены 80 детей с ВПГ от 3 до 17 лет. Пациенты были разделены на 3 группы анализа: группа I (n=14) – дети с ВПГ, которым ранее не выполнялись какие-либо хирургические вмешательства и эндоскопическое лигирование ВРВП (ЭЛВРВП) выполнено на фоне острого кровотечения либо после медикаментозного гемостатического лечения. Во II группу (n=37) включены пациенты, которым ЭЛВРВП выполнено после неудовлетворительного исхода ранее проведенных хирургических вмешательств. В группу III вошли 29 детей, которым выполнены только операции азигопортального разобщения. Проведен сравнительный анализ выраженности ВРВП до и после сеансов ЭЛВРВП, а также анализ чатстоты рецидивов кровотечений в группах сравнения.</p></sec><sec><title>Результаты</title><p>Результаты. Согласно результатам исследований, в 44,4 % случаях в I группе отмечены рецидивы гастроэзофагеальных геморрагий. Во II группе 37 пациентам всего выполнены 68 сеансов этапного ЭЛВРВП. По данным контрольных эндоскопических исследований отмечено достоверное снижение риска кровотечения из ВРВП между сеансами лигирования (p=0,001) ЭЛВРВП. За период наблюдения во II группе рецидивы кровотечений из ВРВП отмечены у 6 (16,2 %) пациентов. В то время как у 10 (34,5 %) детей III группы в послеоперационном периоде отмечены рецидивы гастроэзофагеальных геморрагий. Анализ показал достоверную корреляцию наличия «красных маркеров» с рецидивами эпизодов кровотечений у детей II группы после ЭЛРВП (r=0,32; p=0,05). Анализ причин рецидивных гастроэзофагеальных кровотечений у детей III группы не выявил достоверных различий по таким параметрам, как степень ВРВП и «красный маркер».</p></sec><sec><title>Заключение</title><p>Заключение. Таким образом, ЭЛВРВП является безопасным и эффективным методом вторичной профилактики кровотечений ВРВП. Вопрос касательно первичной меры профилактики гастроэзофагеальных геморрагий требует дальнейшего изучения.</p></sec></abstract><trans-abstract xml:lang="en"><p>The objective of the work was to study the efficacy of minimally invasive endoscopic treatment of esophageal varices (EV) in children with extrahepatic portal hypertension (EHPH).</p><sec><title>Methods and Materials</title><p>Methods and Materials. Eighty children aged 3 to 17 years of age with EHPH included in this study. The patients were divided into three analysis groups. The group I (n=14) included children with EHPH who had not previously undergone any surgical interventions and endoscopic ligation of EV was performed against the background of acute bleeding or after medical hemostatic treatment. The group II (n=37) included patients who had undergone the endoscopic treatment of EV after an unsatisfactory outcome of previously performed surgical interventions. The group III included 29 children who underwent only azygos-portal disconnection procedures. We performed the comparative analysis of the severity of EV before and after sessions of the endoscopic treatment of EV, as well as the analysis of the frequency of recurrent bleedings in comparison groups.</p></sec><sec><title>Results</title><p>Results. According to the research results, recurrent gastroesophageal hemorrhages were noted in 44.4 % of cases in the group I. In the group II, 37 patients underwent a total of 68 sessions of the stage endoscopic treatment of EV. According to the control endoscopic examinations, there was a significant reduction in the risk of bleeding from EV between ligation sessions (p=0.001) of the endoscopic treatment of EV. During the follow-up period, in the group II, recurrent bleedings from EV were noted in 6 (16.2 %) patients. Whereas in 10 (34.5 %) children of the group III, recurrent gastroesophageal hemorrhages were noted in the postoperative period. The analysis showed a significant correlation of the presence of «red flags» with recurrent episodes of bleedings in children of the group II after the endoscopic treatment of EV (r=0.32 p=0.05). Analysis of the causes of recurrent gastroesophageal bleedings in children of the group III did not reveal significant differences in such parameters as the degree of EV and «red flags».</p></sec><sec><title>Conclusion</title><p>Conclusion. Thus, the endoscopic treatment of EV is a safe and effective method of secondary prevention of bleedings from EV. The question concerning the primary prevention of gastroesophageal hemorrhages require further study.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>варикозное расширение вен пищевода</kwd><kwd>кровотечение</kwd><kwd>внепеченочная портальная гипертензия</kwd><kwd>эндоскопическое лигирование</kwd><kwd>азигопортальное разобщение</kwd><kwd>эктопический варикс</kwd></kwd-group><kwd-group xml:lang="en"><kwd>esophageal varices</kwd><kwd>bleeding</kwd><kwd>extrahepatic portal hypertension</kwd><kwd>endoscopic ligation</kwd><kwd>azygos-portal disconnectio</kwd><kwd>ectopic varix</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Разумовский А. Ю., Рачков В. Е. Хирургическое лечение портальной гипертензии у детей. М.: МИА, 2012. 480 с.</mixed-citation><mixed-citation xml:lang="en">Razumovskij A. Ju., Rachkov V. E. Hirurgicheskoe lechenie portal’noj gipertenzii u detej. 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