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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">grekov</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник хирургии имени И.И. Грекова</journal-title><trans-title-group xml:lang="en"><trans-title>Grekov's Bulletin of Surgery</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0042-4625</issn><issn pub-type="epub">2686-7370</issn><publisher><publisher-name>Federal State Budgetary Educational Institution of Higher Education «Academician I.P. Pavlov First St. Petersburg State Medical University» of the Ministry of Healthcare of the Russion Federation, FSBEI HE I.P.Pavlov SPbSMU MOH Russia</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24884/0042-4625-2024-183-4-77-84</article-id><article-id custom-type="elpub" pub-id-type="custom">grekov-2414</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Современные тенденции и приоритеты в лечении хронической анальной трещины</article-title><trans-title-group xml:lang="en"><trans-title>Modern trends and priority in treatment of chronic anal fissure</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3974-0781</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алиев</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Aliev</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Алиев Садай Агалар оглы, доктор медицинских наук, профессор кафедры хирургических болезней № 1</p><p> Баку, ул. Самеда Вургуна, д. 163A</p></bio><bio xml:lang="en"><p>Aliev Saday A., Dr. of Sci. (Med), Professor of the Department of Surgical Diseases № 1</p><p>163А, Sameda Vurguna str., Baku</p></bio><email xlink:type="simple">adayaliyev1948@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2848-7370</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алиев</surname><given-names>Э. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Aliev</surname><given-names>E. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Алиев Эмиль Садай оглы, кандидат медицинских наук, старший лаборант кафедры хирургических болезнейN№ 1</p><p> Баку, ул. Самеда Вургуна, д. 163A</p></bio><bio xml:lang="en"><p>Aliev Emil S., Cand. of Sci. (Med), Assistant of the Department of Surgical Diseases № 1</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Азербайджанский медицинский университет</institution><country>Азербайджан</country></aff><aff xml:lang="en"><institution>Azerbaijan Medical University</institution><country>Azerbaijan</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>23</day><month>07</month><year>2024</year></pub-date><volume>183</volume><issue>4</issue><fpage>77</fpage><lpage>84</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Алиев С.А., Алиев Э.С., 2024</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="ru">Алиев С.А., Алиев Э.С.</copyright-holder><copyright-holder xml:lang="en">Aliev S.A., Aliev E.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.vestnik-grekova.ru/jour/article/view/2414">https://www.vestnik-grekova.ru/jour/article/view/2414</self-uri><abstract><p>В статье рассмотрены современное состояние проблемы и приоритеты в лечении хронической анальной трещины по данным литературы. Последовательно изложены стандартные медикаментозные, хирургические и другие методы лечения с оценкой их эффективности, преимуществ и недостатков. На основании анализа данных литературы показано, что иссечение трещины в сочетании с дозированной боковой подкожной сфинктеротомией по-прежнему остается «золотым стандартом» лечения хронической анальной трещины. С учетом пересмотра традиционно устоявшейся парадигмы и наметив шейся тенденции к мульти дисциплинарному подходу к проблеме обосновано использование комбинированных и малоинвазивных сфинктеросберегающих методов лечения. Описано применение ботулинотоксина, различных вариантов анопластики, чрескожной нейростимуляции, лазерной вапоризации и пневмобаллонной дилатации анального сфинктера. Представлены возможности использования аутологичной плазмы, обогащенной тромбоцитарными факторами роста и аутологичных клеток жирового происхождения, применяемых в качестве клеточной (тканевой) трансплантации.</p><p> </p></abstract><trans-abstract xml:lang="en"><p>The article discusses the current state of the problem and priorities in the treatment of chronic anal fissures according to literature data. We described consistently standard medical, surgical and other treatment methods with an assessment of their advantages and disadvantages. Based on the analysis of literature data, it is shown that fissure excision in combination with dosed form of subcutaneous sphincterotomy still remains the «gold standard» for the treatment of chronic anal fissure. Taking into account the revision of the traditionally established paradigm and the emerging trends towards a multidisciplinary approach to the problem, the use of combined and minimally invasive sphincter-sparing treatment methods is justified. The use of botulinum toxin, various options for anoplasty, transcutaneous neurostimulation, laser vaporization and pneumoballoon dilatation of the anal sphincter are described. The possibilities of using autologous plasma enriched with platelet growth factors and autologous cells of adipose origin used as cell (tissue) transplantation are presented.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>хроническая анальная трещина</kwd><kwd>медикаментозная терапия</kwd><kwd>хирургическое лечение</kwd><kwd>иссечение трещины</kwd><kwd>боковая подкожная сфинктеротомия</kwd><kwd>ботулинический токсин</kwd><kwd>анопластика</kwd><kwd>чрескожная нейростимуляция</kwd><kwd>баллонная дилатация</kwd><kwd>аутологичная плазма</kwd><kwd>аутологичные клетки жирового происхождения</kwd></kwd-group><kwd-group xml:lang="en"><kwd>chronic anal fissure</kwd><kwd>drug therapy</kwd><kwd>surgical treatment</kwd><kwd>fissure excision</kwd><kwd>lateral subcutaneous sphincterotomy</kwd><kwd>botulinum toxin</kwd><kwd>anoplasty</kwd><kwd>transcutaneous neurostimulation</kwd><kwd>balloon dilatation</kwd><kwd>autologous plasma</kwd><kwd>autologous cells of adipose origin</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Arisoy O., Şengul N., Çakir A. 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