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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">grekov</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник хирургии имени И.И. Грекова</journal-title><trans-title-group xml:lang="en"><trans-title>Grekov's Bulletin of Surgery</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0042-4625</issn><issn pub-type="epub">2686-7370</issn><publisher><publisher-name>Federal State Budgetary Educational Institution of Higher Education «Academician I.P. Pavlov First St. Petersburg State Medical University» of the Ministry of Healthcare of the Russion Federation, FSBEI HE I.P.Pavlov SPbSMU MOH Russia</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24884/0042-4625-2024-183-6-48-53</article-id><article-id custom-type="elpub" pub-id-type="custom">grekov-2499</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОПЫТ РАБОТЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>EXPERIENCE OF WORK</subject></subj-group></article-categories><title-group><article-title>Влияние ожирения на тяжесть, исход и осложнения острого панкреатита</article-title><trans-title-group xml:lang="en"><trans-title>Impact of obesity on the severity, outcome and complications of acute pancreatitis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5859-7928</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Капралов</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kapralov</surname><given-names>S. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Капралов Сергей Владимирович, доктор медицинских наук, доцент, зав. кафедрой факультетской хирургии и онкологии</p><p>410012, г. Саратов, ул. Большая Казачья, д. 112</p></bio><bio xml:lang="en"><p>Kapralov Sergey V., Dr. of Sci. (Med.), Associate Professor, Head of the Department of Faculty Surgery and Oncology</p><p>112, Bolshaya Kazachia str., Saratov, 410012</p></bio><email xlink:type="simple">sergejkapralov@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0008-0044-189X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Потапов</surname><given-names>Д. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Potapov</surname><given-names>D. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Потапов Дмитрий Юрьевич, кандидат медицинских наук, доцент кафедры факультетской хирургии и онкологии</p><p>410012, г. Саратов, ул. Большая Казачья, д. 112</p></bio><bio xml:lang="en"><p>Potapov Dmitry Yu., Cand. of Sci. (Med.), Associate Professor of the Department of Faculty Surgery and Oncology</p><p>112, Bolshaya Kazachia str., Saratov, 410012</p></bio><email xlink:type="simple">potapovmed@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0006-9530-4016</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Наматулин</surname><given-names>Р. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Namatulin</surname><given-names>R. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Наматулин Руслан Султанбахмудович, ординатор кафедры факультетской хирургии и онкологии</p><p>410012, г. Саратов, ул. Большая Казачья, д. 112</p></bio><bio xml:lang="en"><p>Namatulin Ruslan S., Resident of the Department of Faculty Surgery and Oncology</p><p>112, Bolshaya Kazachia str., Saratov, 410012</p></bio><email xlink:type="simple">rus.namatulin@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0007-5006-2890</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Прохницкий</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Prohnitsky</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Прохницкий Алексей Валерьевич, ассистент кафедры факультетской хирургии и онкологии</p><p>410012, г. Саратов, ул. Большая Казачья, д. 112</p></bio><bio xml:lang="en"><p>Prohnitsky Aleksey V., Assistant of the Department of Faculty Surgery and Oncology</p><p>112, Bolshaya Kazachia str., Saratov, 410012</p></bio><email xlink:type="simple">a.procha67@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Саратовский государственный медицинский университет им. В.И. Разумовского<country>Россия</country></aff><aff xml:lang="en">Saratov State Medical University named after V. I. Razumovsky<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>30</day><month>01</month><year>2025</year></pub-date><volume>183</volume><issue>6</issue><fpage>48</fpage><lpage>53</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Капралов С.В., Потапов Д.Ю., Наматулин Р.С., Прохницкий А.В., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Капралов С.В., Потапов Д.Ю., Наматулин Р.С., Прохницкий А.В.</copyright-holder><copyright-holder xml:lang="en">Kapralov S.V., Potapov D.Y., Namatulin R.S., Prohnitsky A.V.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.vestnik-grekova.ru/jour/article/view/2499">https://www.vestnik-grekova.ru/jour/article/view/2499</self-uri><abstract><sec><title>ЦЕЛЬ</title><p>ЦЕЛЬ. Изучить влияние ожирения на тяжесть течения острого панкреатита (ОП), его исходы и осложнения.</p></sec><sec><title>МЕТОДЫ И МАТЕРИАЛЫ</title><p>МЕТОДЫ И МАТЕРИАЛЫ. В исследование включено 212 пациентов с ОП. Среди больных 58 % были мужчинами, а 42 % – женщинами. Тяжесть ОП была легкой в 63,2 %, средней в 21,7 % и тяжелой(ТОП) – в 15,1 % случаев. Средний возраст пациентов составил 52 года. Органная недостаточность присутствовала в 20,3 % всех случаев ОП, у 52,3 % больных с ОП средней тяжести и в 59,4 % при ТОП. Общая летальность составила 6,6 %, при легком ОП и ОП средней тяжести летальных исходов не отмечалось, при ТОП летальность составила 43,8 %. Для диагностики ожирения применяли методику вычисления индекса массы тела (ИМТ). Наличие ожирения констатировали при ИМТ≥30 кг/м2. Количество больных с ожирением составило 39,6 % от всех больных с ОП. Для сравнения групп пациентов были использованы U-критерий Манна – Уитни и тест Краскелла – Уоллиса. Для сравнения долей больных в различных группах применяли критерий χ2.</p></sec><sec><title>РЕЗУЛЬТАТЫ</title><p>РЕЗУЛЬТАТЫ. При изучении среднего ИМТ и доли больных с ожирением не выявлено достоверных различий в их величине в зависимости от степени тяжести ОП. Не выявлено достоверных различий в величине среднего ИМТ и доли больных с ожирением у выживших и умерших пациентов с ОП, а также у выживших и умерших пациентов с ТОП. выживших больных выявлены достоверные различия в значении среднего ИМТ и в доле пациентов с ожирением. Не выявлены различия в значениях среднего ИМТ и доли больных с ожирением в группах больных ОП без и с осложнениями.</p></sec><sec><title>ЗАКЛЮЧЕНИЕ</title><p>ЗАКЛЮЧЕНИЕ. Ожирение значимо не влияет на степень тяжести и частоту осложнений у пациентов с ОП.</p></sec></abstract><trans-abstract xml:lang="en"><p>The OBJECTIVE was to study the effect of obesity on the severity of acute pancreatitis (AP), its outcome and complications.</p><sec><title>METHODS AND MATERIALS</title><p>METHODS AND MATERIALS. The study included 212 patients with AP. Among the patients, 58 % (n=123) were men, and 42 % (n=89) were women. The severity of AP was mild in 63.2 %, moderate in 21.7 % and severe (SAP) in 15.1 % of cases. The average age of the patients was 52 years. Organ failure (both transient and persistent) was present in 20.3 % of all cases of AP, in 52.3 % of patients with moderate AP and in 59.4 % with SAP. The total mortality rate was 6.6 %, with mild and moderate AP, no deaths were noted, whereas with severe AP, the mortality rate was 43.8 %. The method of calculating body mass index (BMI) was used to diagnose obesity. The presence of obesity was noted at BMI of≥30 kg/m2. The number of obese patients was 39.6 % of all patients with AP. The Mann – Whitney U-test was used to compare patient groups. The criterion χ2 was used to compare the proportions of patients in different groups.</p></sec><sec><title>RESULTS</title><p>RESULTS. When studying the average BMI and the proportion of obese patients, there were no significant differences in their values depending on the severity of AP. There were also no significant differences in the value of the average BMI and the proportion of obese patients in survivors and deceased patients with AP, as well as in survivors and deceased patients with SAP. Whereas, the surviving patients showed significant differences in the value of the average BMI and in the proportion of obese patients. There were no significant differences in the values of the average BMI and the proportion of obese patients in the groups of patients with OP without and with complications.</p></sec><sec><title>CONCLUSION</title><p>CONCLUSION. Obesity does not significantly influence on the severity and frequency of complications in patients with AP.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>острый панкреатит</kwd><kwd>ожирение</kwd><kwd>осложнения острого панкреатита</kwd><kwd>летальность при остром панкреатите</kwd></kwd-group><kwd-group xml:lang="en"><kwd>acute pancreatitis</kwd><kwd>obesity</kwd><kwd>complications of acute pancreatitis</kwd><kwd>mortality in acute pancreatitis</kwd></kwd-group><funding-group xml:lang="ru"><funding-statement>отсутствует</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Banks P. A., Bollen T. L., Dervenis C. et al. 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