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<article article-type="review-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">grekov</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник хирургии имени И.И. Грекова</journal-title><trans-title-group xml:lang="en"><trans-title>Grekov's Bulletin of Surgery</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0042-4625</issn><publisher><publisher-name>Federal State Budgetary Educational Institution of Higher Education «Academician I.P. Pavlov First St. Petersburg State Medical University» of the Ministry of Healthcare of the Russion Federation, FSBEI HE I.P.Pavlov SPbSMU MOH Russia</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24884/0042-4625-2025-184-1-99-106</article-id><article-id custom-type="elpub" pub-id-type="custom">grekov-2539</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Защита головного мозга при хирургических вмешательствах на дуге аорты: современное состояние проблемы</article-title><trans-title-group xml:lang="en"><trans-title>Brain protection during aortic arch surgery: current state of problem</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1505-0847</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хомушку</surname><given-names>Д. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Khomushku</surname><given-names>D. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Хомушку Дадар-оол Валерьевич, аспирант отделения хирургии аорты и коронарных артерий</p><p>630055, г. Новосибирск, ул. Речкуновская, д. 15</p></bio><bio xml:lang="en"><p>Khomushku Dadar-ool V., Postgraduate Student of the Department of Surgery of the Aorta and Coronary Arteries</p><p>15, Rechkunovskaya str., Novosibirsk, 630055</p></bio><email xlink:type="simple">dadarool_khomushku@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9940-3541</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сирота</surname><given-names>Д. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sirota</surname><given-names>D. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сирота Дмитрий Андреевич, доктор медицинских наук, зав. научно-исследовательским отделом хирургии аорты, коронарных и периферических артерий института патологии кровообращения, врач-сердечно-сосудистый хирург отделения хирургии аорты и коронарных артерий, Национальный медицинский исследовательский центр имени академика Е. Н. Мешалкина; ассистент кафедры сердечно-сосудистой хирургии факультета повышения квалификации и профессиональной переподготовки, Новосибирский государственный медицинский университет</p><p>630055, г. Новосибирск, ул. Речкуновская, д. 15</p><p>630091, г. Новосибирск, Красный пр., д. 52</p></bio><bio xml:lang="en"><p>Sirota Dmitry A., Dr. of Sci. (Med.), Head of the Research Department of Surgery of the Aorta, Coronary and Peripheral Arteries of the Institute of Circulatory Pathology, Cardiovascular surgeon, Department of Aortic and Coronary Artery Surgery, National Medical Research Center named after Academician E. N. Meshalkin; Assistant of the Department of Cardiovascular Surgery, Faculty of Advanced Training and Professional Retraining, Novosibirsk State Medical University</p><p>15, Rechkunovskaya str., Novosibirsk, 630055</p><p>52, Krasny pr., Novosibirsk, 630091</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1176-8125</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шаданов</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Shadanov</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шаданов Алдар Андреевич, врач – сердечно-сосудистый хирург отделения хирургии аорты и коронарных артерий</p><p>630055, г. Новосибирск, ул. Речкуновская, д. 15</p></bio><bio xml:lang="en"><p>Shadanov Aldar A., Cardiovascular Surgeon, Department of Aortic and Coronary Artery Surgery</p><p>15, Rechkunovskaya str., Novosibirsk, 630055</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6661-7826</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Едемский</surname><given-names>А. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Edemskiy</surname><given-names>A. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Едемский Александр Геннадьевич, кандидат медицинских наук, врач – сердечно-сосудистый хирург отделения хирургии аорты и коронарных артерий</p><p>630055, г. Новосибирск, ул. Речкуновская, д. 15</p></bio><bio xml:lang="en"><p>Edemskiy Alexander G., Cand. of Sci. (Med.), Cardiovascular Surgeon of the Department of Surgery of the Aorta and Coronary Arteries</p><p>15, Rechkunovskaya str., Novosibirsk, 630055</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9818-8678</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чернявский</surname><given-names>А. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Chernyavskiy</surname><given-names>A. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Чернявский Александр Михайлович, доктор медицинских наук, профессор, чл.-корр. РАН, заслуженный деятель науки РФ, генеральный директор, Национальный медицинский исследовательский центр имени академика Е. Н. Мешалкина; зав. кафедрой сердечно-сосудистой хирургии факультета повышения квалификации и профессиональной переподготовки врачей, Новосибирский государственный медицинский университет</p><p>630055, г. Новосибирск, ул. Речкуновская, д. 15</p><p>630091, г. Новосибирск, Красный пр., д. 52</p><p> </p></bio><bio xml:lang="en"><p>Chernyavskiy Alexander M., Dr. of Sci. (Med.), Professor, Corresponding Member of the RAS, Honored Scientist of the Russian Federation, General Director, National Medical Research Center named after Academician E. N. Meshalkin; Head of the Department of Cardiovascular Surgery, Faculty of Advanced Training and Professional Retraining of Physicians, Novosibirsk State Medical University</p><p>15, Rechkunovskaya str., Novosibirsk, 630055</p><p>52, Krasny pr., Novosibirsk, 630091</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Национальный медицинский исследовательский центр имени академика е. Н. Мешалкина</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Medical Research Center named after Academician E. N. Meshalkin</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Национальный медицинский исследовательский центр имени академика е. Н. Мешалкина; Новосибирский государственный медицинский университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Medical Research Center named after Academician E. N. Meshalkin; Novosibirsk State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>27</day><month>04</month><year>2025</year></pub-date><volume>184</volume><issue>1</issue><fpage>99</fpage><lpage>106</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Хомушку Д.В., Сирота Д.А., Шаданов А.А., Едемский А.Г., Чернявский А.М., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Хомушку Д.В., Сирота Д.А., Шаданов А.А., Едемский А.Г., Чернявский А.М.</copyright-holder><copyright-holder xml:lang="en">Khomushku D.V., Sirota D.A., Shadanov A.A., Edemskiy A.G., Chernyavskiy A.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.vestnik-grekova.ru/jour/article/view/2539">https://www.vestnik-grekova.ru/jour/article/view/2539</self-uri><abstract><p>Хирургия дуги аорты является одним из самых сложных разделов сердечно-сосудистой хирургии. Реконструктивные вмешательства на дуге аорты сопряжены с высокими рисками из-за особенностей анатомии и технической сложности вмешательства. Для защиты головного мозга во время операции на дуге аорты широко применяется антеградная перфузия головного мозга в сочетании с гипотермией. Антеградная перфузия может выполняться в унилатеральном или билатеральном варианте. На данный момент отсутствуют четкие рекомендации относительно ведения пациентов, оперируемых на дуге аорты. В данном обзоре освещены основные методы защиты головного мозга в аортальной хирургии, а также представлены результаты имеющихся исследований, сравнивающих унилатеральную и билатеральную перфузии головного мозга. Рассмотрены обоснования различных исследователей при выборе каждой из двух предложенных методик для снижения риска неврологических осложнений.</p></abstract><trans-abstract xml:lang="en"><p>Aortic arch surgery is one of the most challenging field of cardiovascular surgery. Reconstructive interventions on the aortic arch are associated with high risks due to the peculiarities of anatomy and technical complexity of surgical intervention. Antegrade cerebral perfusion in combination with hypothermia is widely used to protect the brain during aortic arch surgery. Antegrade cerebral perfusion can be performed in unilateral or bilateral way. Now, there is no clear guidelines regarding the management of patients operated on the aortic arch. This review highlights the main methods of protecting the brain during aortic arch surgery and shows the results of the studies comparing antegrade unilateral brain perfusion with bilateral one. We reviewed rationale of various researchers in choosing two proposed methods to reduce the risk of neurological complications.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>циркуляторный арест</kwd><kwd>дуга аорты</kwd><kwd>унилатеральная перфузия</kwd><kwd>билатеральная перфузия</kwd><kwd>защита головного мозга</kwd></kwd-group><kwd-group xml:lang="en"><kwd>circulatory arrest</kwd><kwd>aortic arch</kwd><kwd>unilateral perfusion</kwd><kwd>bilateral perfusion</kwd><kwd>neuroprotection</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Гордеев М. Л., Успенский В. Е., Баканов А. Ю. и др. Реконструктивные вмешательства на дуге аорты при хирургическом лечении аневризм и расслоений восходящего отдела аорты. Патология кровообращения и кардиохирургия. 2016. Т. 20, № 4. 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