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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">grekov</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник хирургии имени И.И. Грекова</journal-title><trans-title-group xml:lang="en"><trans-title>Grekov's Bulletin of Surgery</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0042-4625</issn><issn pub-type="epub">2686-7370</issn><publisher><publisher-name>Federal State Budgetary Educational Institution of Higher Education «Academician I.P. Pavlov First St. Petersburg State Medical University» of the Ministry of Healthcare of the Russion Federation, FSBEI HE I.P.Pavlov SPbSMU MOH Russia</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24884/0042-4625-2025-184-4-94-101</article-id><article-id custom-type="elpub" pub-id-type="custom">grekov-2548</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБЗОРЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>REVIEWS</subject></subj-group></article-categories><title-group><article-title>Лапароскопическая правосторонняя гемиколэктомия: интракорпоральный и экстракорпоральный анастомозы</article-title><trans-title-group xml:lang="en"><trans-title>Laparoscopic right hemicolectomy: intracorporeal and extracorporeal anastomosis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6188-6093</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сажин</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sazhin</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сажин Александр Вячеславович, доктор медицинских наук, профессор, член-корреспондент РАН, директор Института хирургии, зав. кафедрой факультетской хирургии № 1 Института хирургии; врач-хирург, онколог</p><p>117513, Москва, ул. Островитянова, д. 1</p><p>142770, Москва, ул. Сосенский Стан, д. 8 с 3</p></bio><bio xml:lang="en"><p>Sazhin Alexander V., Dr. of Sci. (Med.), Professor, Corresponding Member of the RAS, Director of the Institute of Surgery, Head of the Department of Faculty Surgery № 1 of the Institute of Surgery; Surgeon, Oncologist</p><p>1, Ostrovitianova str., Moscow, 117513</p><p>8, build. 3, Sosenskii Stan str., Moscow, 142770</p></bio><email xlink:type="simple">sazhin-av@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9103-6073</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ермаков</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Ermakov</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ермаков Игорь Викторович, кандидат медицинских наук, доцент кафедры факультетской хирургии № 1 Института хирургии, старший научный сотрудник отдела абдоминальной онкологии Института хирургии; врач-хирург, онколог</p><p>117513, Москва, ул. Островитянова, д. 1</p><p>142770, Москва, ул. Сосенский Стан, д. 8 с 3</p></bio><bio xml:lang="en"><p>Ermakov Igor V., Cand. of Sci. (Med.), Associate Professor of the Department of Faculty Surgery № 1 of the Institute of Surgery, Senior Research Fellow of the Department of Abdominal Oncology of the Institute of Surgery; Surgeon, Oncologist</p><p>1, Ostrovitianova str., Moscow, 117513</p><p>8, build. 3, Sosenskii Stan str., Moscow, 142770</p></bio><email xlink:type="simple">iermakov0588@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9773-4953</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ивахов</surname><given-names>Г. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivakhov</surname><given-names>G. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ивахов Георгий Богданович, доктор медицинских наук, профессор кафедры факультетской хирургии № 1 Института хирургии, зам. директора Института хирургии, зав. отделом абдоминальной онкологии Института хирургии; врач-хирург, онколог</p><p>117513, Москва, ул. Островитянова, д. 1</p><p>142770, Москва, ул. Сосенский Стан, д. 8 с 3</p></bio><bio xml:lang="en"><p>Ivakhov Georgy B., Dr. of Sci. (Med.), Professor of the Department of Faculty Surgery № 1 of the Institute of Surgery, Deputy Director of the Institute of Surgery, Head of the Department of Abdominal Oncology of the Institute of Surgery; Surgeon, Oncologist</p><p>1, Ostrovitianova str., Moscow, 117513</p><p>8, build. 3, Sosenskii Stan str., Moscow, 142770</p></bio><email xlink:type="simple">ivakhovsurg@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0001-2598-9965</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тимошенко</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Timoshenko</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тимошенко Никита Андреевич, аспирант кафедры факультетской хирургии № 1 Института хирургии</p><p>117513, Москва, ул. Островитянова, д. 1</p><p>142770, Москва, ул. Сосенский Стан, д. 8 с 3</p></bio><bio xml:lang="en"><p>Timoshenko Nikita A., Postgraduate Student of the Department of Faculty Surgery № 1 of the Institute of Surgery</p><p> </p><p>1, Ostrovitianova str., Moscow, 117513</p><p>8, build. 3, Sosenskii Stan str., Moscow, 142770</p></bio><email xlink:type="simple">dr.timoschenko@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0003-2697-3441</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шихин</surname><given-names>И. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Shikhin</surname><given-names>I. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шихин Иван Сергеевич, младший научный сотрудник отдела абдоминальной онкологии Института хирургии, адъюнкт кафедры факультетской хирургии № 1 Института хирургии; врач-хирург</p><p>117513, Москва, ул. Островитянова, д. 1</p><p>142770, Москва, ул. Сосенский Стан, д. 8 с 3</p></bio><bio xml:lang="en"><p>Shikhin Ivan S., Junior Research Fellow of the Department of Abdominal Oncology of the Institute of Surgery, Associate Professor at the Department of Faculty Surgery № 1 of the Institute of Surgery; Surgeon</p><p>1, Ostrovitianova str., Moscow, 117513</p><p>8, build. 3, Sosenskii Stan str., Moscow, 142770</p></bio><email xlink:type="simple">s.shikhin@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4233-3711</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Морозов</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Morozov</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Морозов Иван Андреевич, ординатор кафедры факультетской хирургии № 1 Института хирургии</p><p>117513, Москва, ул. Островитянова, д. 1</p><p> </p></bio><bio xml:lang="en"><p>Morozov Ilya A., Resident of the Department of Faculty Surgery № 1 of the Institute of Surgery</p><p>1, Ostrovitianova str., Moscow, 117513</p></bio><email xlink:type="simple">Lonny8@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Российский Национальный Исследовательский Медицинский Университет имени Н. И. Пирогова; Московский многопрофильный клинический центр «Коммунарка»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pirogov Russian National Research Medical University; Moscow Multidisciplinary Clinical Center «Kommunarka»</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Российский Национальный Исследовательский Медицинский Университет имени Н. И. Пирогова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pirogov Russian National Research Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>22</day><month>10</month><year>2025</year></pub-date><volume>184</volume><issue>4</issue><fpage>94</fpage><lpage>101</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сажин А.В., Ермаков И.В., Ивахов Г.Б., Тимошенко Н.А., Шихин И.С., Морозов И.А., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Сажин А.В., Ермаков И.В., Ивахов Г.Б., Тимошенко Н.А., Шихин И.С., Морозов И.А.</copyright-holder><copyright-holder xml:lang="en">Sazhin A.V., Ermakov I.V., Ivakhov G.B., Timoshenko N.A., Shikhin I.S., Morozov I.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.vestnik-grekova.ru/jour/article/view/2548">https://www.vestnik-grekova.ru/jour/article/view/2548</self-uri><abstract><sec><title>ВВЕДЕНИЕ</title><p>ВВЕДЕНИЕ. Лапароскопический доступ в хирургии колоректального рака является золотым стандартом. Формирование анастомоза при лапароскопической правосторонней гемиколэктомии возможно как экстракорпорально, так и интракорпорально. Необходимость навыков интракорпорального шва, а также скептицизм в отношении безопасности интракорпорального анастомоза, отражаются в ограниченном его применении на практике. Результаты проведенных исследований противоречивы и требуют изучения данного вопроса.</p><p>ЦЕЛЬ данной работы – провести обзор имеющейся литературы и выполнить анализ опубликованных исследований как для интракорпорального анастомоза, так и для экстракорпорального анастомоза в рамках оценки хирургической эффективности и безопасности.</p></sec><sec><title>МЕТОДЫ И МАТЕРИАЛЫ</title><p>МЕТОДЫ И МАТЕРИАЛЫ. Проведен поиск рандомизированных исследований в электронных базах данных PubMed, eLibrary, Cochrane Library, Google Scholar, используя комбинацию ключевых слов. В ходе поиска и изучения материалов в окончательный обзор и анализ включено 8 рандомиизированных контролируемых исследований и 6 метаанализов.</p></sec><sec><title>РЕЗУЛЬТАТЫ</title><p>РЕЗУЛЬТАТЫ. В ходе первоначального поиска в базах данных выявлено в общей сложности 1502 работы. После исключения повторяющихся ссылок и тщательного полнотекстового изучения материалов были отобраны 8 рандомизированных контролируемых исследований, 6 систематических обзоров и метаанализов. Длительность операции и стоимость лечения в группах интра- и экстракорпорального анастомоза сопоставимы. Интракорпоральный анастомоз снижает уровень хирургического стресса, уменьшает длину необходимой минилапаротомии, сокращает сроки восстановления желудочно-кишечного тракта и продолжительность госпитализации без увеличения частоты интраабдоминальных осложнений. При экстракорпоральном анастомозе увеличивается частота раневой инфекции, пареза кишечника средней степени тяжести, послеоперационных вентральных грыж.</p></sec><sec><title>ЗАКЛЮЧЕНИЕ</title><p>ЗАКЛЮЧЕНИЕ. Интракорпоральный анастомоз при лапароскопической правосторонней гемиколэктомии можно рассматривать как альтернативу экстракорпоральному, однако вопрос различия и преимуществ в хирургических результатах остается открытым ввиду недостатка исследований.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Introduction</title><p>Introduction. The laparoscopic approach is the gold standard in colorectal cancer surgery. The formation of an anastomosis during laparoscopic right hemicolectomy is possible both extracorporeal and intracorporeal. However, the need for advanced intracorporeal suturing skills and concerns about the safety of intracorporeal anastomosis have limited its use in practice. Contradictory study results highlight the need for further research.</p><p>The objective of this study was to review the available literature and analyze the published studies for both intracorporeal anastomosis and extracorporeal anastomosis, focusing on surgical efficacy and safety.</p></sec><sec><title>Materials and Methods</title><p>Materials and Methods. Randomized trials were searched in electronic databases in PubMed, eLIBRARY, the Cochrane Library, and Google Scholar using predefined keywords. During the search and study of materials, 8 randomized controlled trials and 6 meta-analyses were included in the final review and analysis.</p></sec><sec><title>Results</title><p>Results. An initial database search revealed a total of 1,502 papers. After removing duplicates and reviewing texts, eight randomized controlled trials and six systematic reviews and meta-analyses were analyzed. Surgery duration and treatment costs were comparable between intracorporeal and extracorporeal anastomosis groups. Intracorporeal anastomosis was linked to reduced surgical stress, shorter incision length, faster gastrointestinal recovery, and shorter hospital stays, without increased intra-abdominal complications. Extracorporeal anastomosis showed higher rates of wound infections, moderate intestinal paresis, and postoperative ventral hernias.</p></sec><sec><title>Conclusion</title><p>Conclusion. Intracorporeal anastomosis may be a viable alternative to extracorporeal anastomosis in laparoscopic right hemicolectomy. However, the limited number of studies leaves questions about their comparative advantages unresolved. </p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>лапароскопическая правосторонняя гемиколэктомия</kwd><kwd>лапароскопически ассистированная правосторонняя гемиколэктомия</kwd><kwd>интракорпоральный анастомоз</kwd><kwd>экстракорпоральный анастомоз</kwd></kwd-group><kwd-group xml:lang="en"><kwd>laparoscopic right hemicolectomy</kwd><kwd>laparoscopy-assisted right hemicolectomy</kwd><kwd>intracorporeal anastomosis</kwd><kwd>extracorporeal anastomosis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ansa B. E., Coughlin S. S., Alema-Mensah E. et al. Evaluation of Colorectal Cancer Incidence Trends in the United States (2000-2014). J. Clin. Med. 2018. Vol. 7. P. 22. https://doi.org/10.3390/jcm7020022.</mixed-citation><mixed-citation xml:lang="en">Ansa B. 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