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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">grekov</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник хирургии имени И.И. Грекова</journal-title><trans-title-group xml:lang="en"><trans-title>Grekov's Bulletin of Surgery</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0042-4625</issn><issn pub-type="epub">2686-7370</issn><publisher><publisher-name>Federal State Budgetary Educational Institution of Higher Education «Academician I.P. Pavlov First St. Petersburg State Medical University» of the Ministry of Healthcare of the Russion Federation, FSBEI HE I.P.Pavlov SPbSMU MOH Russia</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24884/0042-4625-2017-176-1-34-41</article-id><article-id custom-type="elpub" pub-id-type="custom">grekov-291</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ВОПРОСЫ ОБЩЕЙ НЕОТЛОЖНОЙ ХИРУРГИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>PROBLEMS OF GENERAL AND SPECIAL SURGERY</subject></subj-group></article-categories><title-group><article-title>МЕТАБОЛИЧЕСКАЯ ХИРУРГИЯ В КОРРЕКЦИИ ЖИРОВОЙ БОЛЕЗНИ ПЕЧЕНИ</article-title><trans-title-group xml:lang="en"><trans-title>METABOLIC SURGERY IN CORRECTION OF FATTY LIVER DISEASE</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фишман</surname><given-names>М. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Fishman</surname><given-names>M. B.</given-names></name></name-alternatives><email xlink:type="simple">michaelfishman@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Карев</surname><given-names>В. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Karev</surname><given-names>V. E.</given-names></name></name-alternatives><email xlink:type="simple">vadimkarev@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ван</surname><given-names>Ян.</given-names></name><name name-style="western" xml:lang="en"><surname>Yan</surname><given-names>V.</given-names></name></name-alternatives><email xlink:type="simple">bbh1985@qq.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Соколова</surname><given-names>Д. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sokolova</surname><given-names>D. A.</given-names></name></name-alternatives><email xlink:type="simple">dashulya-280591@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мицинская</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Mitsinskaya</surname><given-names>A. I.</given-names></name></name-alternatives><email xlink:type="simple">sashaart2012@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мицинский</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Mitsinskiy</surname><given-names>M. A.</given-names></name></name-alternatives><email xlink:type="simple">mic-mikhail@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Первый Санкт-Петербургский государственный медицинский университет им. акад. И. П. Павлова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>I. P.Pavlov First Saint-Petersburg State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Научно-исследовательский институт детских инфекций Федерального медико-биологического агентства</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Research Institute of Children Infections</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2017</year></pub-date><pub-date pub-type="epub"><day>28</day><month>02</month><year>2017</year></pub-date><volume>176</volume><issue>1</issue><fpage>34</fpage><lpage>41</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Фишман М.Б., Карев В.Е., Ван Я., Соколова Д.А., Мицинская А.И., Мицинский М.А., 2017</copyright-statement><copyright-year>2017</copyright-year><copyright-holder xml:lang="ru">Фишман М.Б., Карев В.Е., Ван Я., Соколова Д.А., Мицинская А.И., Мицинский М.А.</copyright-holder><copyright-holder xml:lang="en">Fishman M.B., Karev V.E., Yan V., Sokolova D.A., Mitsinskaya A.I., Mitsinskiy M.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.vestnik-grekova.ru/jour/article/view/291">https://www.vestnik-grekova.ru/jour/article/view/291</self-uri><abstract><p>В статье представлены результаты лечения 68 больных, которым в период с 2014 по 2015 г. выполнены операции: лапароскопическая продольная резекция желудка (ЛПРЖ) и лапароскопическое желудочное шунтирование (ЛЖШ). Оценивалась эффективность операций в воздействии на течение неалкогольной жировой болезни печени (НАЖБП). Во время операции выполнялись биопсия печени, гистологические исследования с определением индекса гистологической активности, степень выраженности фиброза по R. G. Knodell, по METAVIR, характер и степень выраженности жировой дистрофии гепатоцитов и внутрипеченочного холестаза. Для оценки морфологических изменений использовалась шкала активности NAS. Результаты оценивались в динамике до 1,5 лет после операции. Результаты фибротеста были в пределах от 0 до 1, в зависимости от тяжести фиброза, с переводом в систему METAVIR (от F0 до F4), системы по Knodell и Ishak. В результате установлено, что происходит улучшение гистологических и функциональных признаков стеатоза печени, воспаления и фиброза. Так, у всех (100%) исходно были признаки НАЖБП, у 12 (22,6%) - фиброз. Полная регрессия НАЖБП имелась в 43 (81,1%) случаях, у 6 (41,%) - признаки ранее существующего фиброза нивелированы. Функциональные пробы печени ухудшались к 6-месячному периоду, к 1 году - приближались к нормальным значениям. Таким образом, бариатрические операции являются эффективным методом воздействия на течение НАЖБП, а фибротест - неинвазивный и достоверный метод оценки состояния печени.</p></abstract><trans-abstract xml:lang="en"><p>The article presents the results of treatment of 68 patients who underwent laparoscopic sleeve gastric resection (LSG) and laparoscopic gastric bypass (LGB) at the period from 2014 to 2015. The efficacy of operations on the course of nonalcoholic fatty liver disease (NAFLD) was estimated. There were performed a liver biopsy and histological studies with determination of histological activity index, the rate of severity of fibrosis according R. G. Knodell scale and METAVIR system, nature and degree of manifestation of steatosis of hepatocytes and intrahepatic cholestasis. NAS activity scale was used to evaluate morphological changes. The results of 1,5-year follow-up study were assessed in dynamics. Fibro Test results were in the range from 0 to 1 depending of fibrosis severity using METAVIR system (from F0 to F4), Knodell and Ishak scales. It was stated that there was an improvement of histological and functional findings in cases of hepatic steatosis, inflammation and fibrosis. All the patients (100%) initially had the signs of NAFLD and 12 patients (22,6%) - fibrosis. The complete regression of NAFLD was noted in 43(81,1%) cases and signs of previous fibrosis were smoothed over in 6 patients (41%). Liver function tests have deteriorated at 6-month period, but tests improved to normal rates at the end of 1-year period. The bariatric surgeries are effective methods of NAFLD treatment and Fibro Test is non-invasive and reliable method of liver state assessment.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ожирение</kwd><kwd>метаболическая хирургия</kwd><kwd>печень</kwd></kwd-group><kwd-group xml:lang="en"><kwd>obesity</kwd><kwd>bariatric surgery</kwd><kwd>liver</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">ВОЗ. Информационный бюллетень № 311 от января 2015 г. Источник: http://www.who.int/mediacentre/factsheets/fs311/ru.</mixed-citation><mixed-citation xml:lang="en">ВОЗ. Информационный бюллетень № 311 от января 2015 г. Источник: http://www.who.int/mediacentre/factsheets/fs311/ru.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Драпкина О. М., Ивашкин В. Т. 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