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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">grekov</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник хирургии имени И.И. Грекова</journal-title><trans-title-group xml:lang="en"><trans-title>Grekov's Bulletin of Surgery</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0042-4625</issn><issn pub-type="epub">2686-7370</issn><publisher><publisher-name>Federal State Budgetary Educational Institution of Higher Education «Academician I.P. Pavlov First St. Petersburg State Medical University» of the Ministry of Healthcare of the Russion Federation, FSBEI HE I.P.Pavlov SPbSMU MOH Russia</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24884/0042-4625-2015-174-2-81-83</article-id><article-id custom-type="elpub" pub-id-type="custom">grekov-43</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ХИРУРГИЯ ОРГАНОВ ЭНДОКРИННОЙ СИСТЕМЫ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>SURGERY OF ORGANS OF ENDOCRINE SYSTEM</subject></subj-group></article-categories><title-group><article-title>РЕЗУЛЬТАТЫ ИССЛЕДОВАНИЯ ГАЛЕКТИНА-3 И ТИРЕОГЛОБУЛИНА У БОЛЬНЫХ С УЗЛОВЫМИ ОБРАЗОВАНИЯМИ ЩИТОВИДНОЙ ЖЕЛЕЗЫ</article-title><trans-title-group xml:lang="en"><trans-title>RESULTS OF RESEARCH OF GALECTIN-3 AND THYROGLOBULIN IN PATIENTS WITH THYROID NODULES</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Олифирова</surname><given-names>О. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Olifirova</surname><given-names>O. S.</given-names></name></name-alternatives><email xlink:type="simple">оlif.ос@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кналян</surname><given-names>С. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Knalyan</surname><given-names>S. V.</given-names></name></name-alternatives><email xlink:type="simple">sofyaknalyan@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Амурская государственная медицинская академия</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Amur State Medical Academy</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>28</day><month>04</month><year>2015</year></pub-date><volume>174</volume><issue>2</issue><fpage>81</fpage><lpage>83</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Олифирова О.С., Кналян С.В., 2015</copyright-statement><copyright-year>2015</copyright-year><copyright-holder xml:lang="ru">Олифирова О.С., Кналян С.В.</copyright-holder><copyright-holder xml:lang="en">Olifirova O.S., Knalyan S.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.vestnik-grekova.ru/jour/article/view/43">https://www.vestnik-grekova.ru/jour/article/view/43</self-uri><trans-abstract xml:lang="en"><p>An investigation of galectin-3 and thyroglobulin using IFA was conducted in 80 patients. A lavage of aspirate from the thyroid gland was obtained by fine-needle aspiration biopsy. It was stated that significant increase of galectin-3 and thyroglobulin was noted in case of high differentiated thyroid carcinoma in comparison with benign nodules. Galectin-3 and thyroglobulin from the lavage of thyroid gland aspirate could be used as an oncological marker for complex differentiated diagnostics of high differentiated thyroid carcinoma and benign nodules.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>узлы щитовидной железы</kwd><kwd>галектин-3</kwd><kwd>тиреоглобулин</kwd><kwd>смыв аспирата щитовидной железы</kwd><kwd>иммуноферментный анализ</kwd></kwd-group><kwd-group xml:lang="en"><kwd>thyroid nodules</kwd><kwd>galectin-3</kwd><kwd>thyroglobulin</kwd><kwd>lavage of thyroid gland aspirate</kwd><kwd>immune-enzyme analysis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Камышников В. С. Онкомаркеры: Методы определения, референтные значения, интерпретация тестов: справочник. М.: МЕДпресс-информ, 2012. 128 с.</mixed-citation><mixed-citation xml:lang="en">Камышников В. С. 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