References

grekov

Вестник хирургии имени И.И. Грекова

Grekov's Bulletin of Surgery

0042-46252686-7370

Federal State Budgetary Educational Institution of Higher Education «Academician I.P. Pavlov First St. Petersburg State Medical University» of the Ministry of Healthcare of the Russion Federation, FSBEI HE I.P.Pavlov SPbSMU MOH Russia

10.24884/0042-4625-2014-173-5-27-30

grekov-574

Research Article

ВОПРОСЫ ОБЩЕЙ НЕОТЛОЖНОЙ ХИРУРГИИ

PROBLEMS OF GENERAL AND SPECIAL SURGERY

ГЕНЕТИЧЕСКИЕ АСПЕКТЫ ХИРУРГИЧЕСКОГО ЛЕЧЕНИЯ БОЛЬНЫХ С НАСЛЕДСТВЕННЫМ РАКОМ МОЛОЧНОЙ ЖЕЛЕЗЫ

GENETICAL ASPECTS OF SURGICAL TREATMENT IN PATIENTS WITH HEREDITARY BREAST CANCER

Бит-Сава

Елена Михайловна

Bit-Sava

E. M.

bit-sava@mail.ru

Первый Санкт-Петербургский государственный медицинский университет им. акад. И. П. Павлова; Санкт-Петербургский государственный педиатрический медицинский университетРоссияFirst Pavlov State Medical University; Saint-Petersburg State Pediatric Medical UniversityRussian Federation

2014

15012018

17352730

2018

Бит-Сава Е.М.

Bit-Sava E.M.

Данная работа распространяется под лицензией Creative Commons Attribution 4.0.

This work is licensed under a Creative Commons Attribution 4.0 License.

https://www.vestnik-grekova.ru/jour/article/view/574

Numerous available results of investigations confirmed the important role of prophylactic bilateral laparoscopic salpingo-oophorectomy and contralateral prophylactic subcutaneous mastectomy in decrease of risks of malignant tumors of the reproductive system when mutation carriers of BRCA1 and BRCA2 presented. Recommendations to surgical treatment of hereditary breast cancer are considered as a very difficult task which should be based on risks and advantages of prophylactic surgical interventions. Presented surgical operations could be applied in mutation carriers of reparation DNA genes and patients with hereditary breast cancer aimed to improve the indices of general survival rate and quality of life.

наследственный рак молочной железыпрофилактическая контралатеральная мастэктомияпрофилактическая билатеральная сальпингоофорэктомияhereditary breast cancerprophylactic contralateral mastectomyprophylactic bilateral salpingo-oophorectomy

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The authors declare that there are no conflicts of interest present.