An analysis of complex examination and treatment of 123 patients with diffuse purulent peritonitis was made. The patients were divided into two groups. The first group consists of 68 patients, whom conservative surgical intervention was performed at the first stage and videoimage endoscopic sanation of the abdominal cavity with the administration of sodium hypochlorite water solution was made at the second stage. The main group consists of 55 patients, who had the same treatment except that the abdominal cavity was processed with pulsating stream of antiseptic with immobilized forms of sodium hypochlorite at the second stage. It is established, that the application of developed technology allows decreasing of the frequency of postoperative complications on 8.3% and postoperative lethality — 4.8%.