An analysis of complex clinical and ultrasonic investigations of the abdominal wall and the following surgery in 42 women with ventral hernia of big size accompanied by the ptosis of the abdomen was made. The patients were divided into two groups, each consisting of 21 patients. The endoprosthesis replacement of defect of the abdominal wall was made with standard polypropylene implant in the first group. The endoprosthesis replacement was complemented by lifting of muscular aponeurotic tissues of the hypogastrium using the implant of the original construction in the second group. The polypropylene endoprosthesis includes the main flap (15×15 cm) with rounded corners and the additional flap (5×40 cm) as a broad band situated at the lower edge of main flap in across-track direction. The increase of physical component of health was noted in 1,8 times in the second group patients and psychological component raised in 2,5 times.