<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">grekov</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник хирургии имени И.И. Грекова</journal-title><trans-title-group xml:lang="en"><trans-title>Grekov's Bulletin of Surgery</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0042-4625</issn><issn pub-type="epub">2686-7370</issn><publisher><publisher-name>Federal State Budgetary Educational Institution of Higher Education «Academician I.P. Pavlov First St. Petersburg State Medical University» of the Ministry of Healthcare of the Russion Federation, FSBEI HE I.P.Pavlov SPbSMU MOH Russia</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24884/0042-4625-2013-172-1-104-107</article-id><article-id custom-type="elpub" pub-id-type="custom">grekov-773</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НАБЛЮДЕНИЯ ИЗ ПРАКТИКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>OBSERVATION FROM PRACTICE</subject></subj-group></article-categories><title-group><article-title>ЭФФЕКТИВНОСТЬ КОЖНОЙ ПЛАСТИКИ И ДЕРМАЛЬНОГО ЭКВИВАЛЕНТА В ЛЕЧЕНИИ ОБШИРНЫХ ЯЗВ ГОЛЕНИ СМЕШАННОГО ГЕНЕЗА</article-title><trans-title-group xml:lang="en"><trans-title>EFFICACY OF DERMOPLASTY AND THE DERMAL EQUIVALENT IN TREATMENT OF VAST LEG ULCERS OF MIXED GENESIS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Андреев</surname><given-names>Дмитрий Юрьевич</given-names></name><name name-style="western" xml:lang="en"><surname>Andreev</surname><given-names>D. Yu.</given-names></name></name-alternatives><email xlink:type="simple">dy.andreev@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Абрамова</surname><given-names>Наталья Викторовна</given-names></name><name name-style="western" xml:lang="en"><surname>Abramova</surname><given-names>N. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Блинова</surname><given-names>Миральда Ивановна</given-names></name><name name-style="western" xml:lang="en"><surname>Blinova</surname><given-names>M. I.</given-names></name></name-alternatives><email xlink:type="simple">mira.blinova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пинаев</surname><given-names>Георгий Петрович</given-names></name><name name-style="western" xml:lang="en"><surname>Pinaev</surname><given-names>G. P.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Санкт-Петербургский государственный медицинский университет; Институт цитологии РАН</institution><country>Россия</country></aff><aff xml:lang="en"><institution>State Pavlov Medical University; Institute of Cytology of the Russian Academy of Sciences</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2013</year></pub-date><pub-date pub-type="epub"><day>16</day><month>01</month><year>2018</year></pub-date><volume>172</volume><issue>1</issue><fpage>104</fpage><lpage>107</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Андреев Д.Ю., Абрамова Н.В., Блинова М.И., Пинаев Г.П., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Андреев Д.Ю., Абрамова Н.В., Блинова М.И., Пинаев Г.П.</copyright-holder><copyright-holder xml:lang="en">Andreev D.Y., Abramova N.V., Blinova M.I., Pinaev G.P.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.vestnik-grekova.ru/jour/article/view/773">https://www.vestnik-grekova.ru/jour/article/view/773</self-uri><trans-abstract xml:lang="en"><p>The most frequent causes of leg ulcers (90–95%) are chronic venous insufficiency (45–60%), obliterating atherosclerosis of the lower extremity arteries (10–20%), diabetes mellitus (15– 25%) and their combinations (10–15%).The leg ulcers, specified as pyoderma gangrenosum, are the rare and severe pathology, which is very often misdiagnosed. The case history of a 58-year old female patient with vast leg ulcers of the both shanks is analyzed. The leg ulcers were caused by pyoderma gangrenosum and chronic venous insufficiency due to the varicose disease. Complete epithelization of both ulcers was achieved by means of dermoplasty combined using the dermal equivalent against the background of system immunosuppressive therapy.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>трофические язвы</kwd><kwd>пиодермия</kwd><kwd>кожная пластика</kwd><kwd>trophic ulcers</kwd><kwd>pyoderma gangrenosum</kwd><kwd>dermal equivalent</kwd><kwd>dermoplasty</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Блинова М. И., Калмыкова Н. В., Юдинцева Н. М. и др. Использование культивируемых клеток кожи человека для лечения трофических язв // Информ. бюл. «Клеточные культуры». 2006. Вып. 21. С. 33–44.</mixed-citation><mixed-citation xml:lang="en">Блинова М. И., Калмыкова Н. В., Юдинцева Н. М. и др. Использование культивируемых клеток кожи человека для лечения трофических язв // Информ. бюл. «Клеточные культуры». 2006. Вып. 21. С. 33–44.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Григорян А. С. Фибробласты в качестве иммуносупрессоров — функциональный эквивалент мультипотентных мезенхимальных стромальных клеток // Клеточная трансплантология. 2007. № 2. С. 24–25.</mixed-citation><mixed-citation xml:lang="en">Григорян А. С. Фибробласты в качестве иммуносупрессоров — функциональный эквивалент мультипотентных мезенхимальных стромальных клеток // Клеточная трансплантология. 2007. № 2. С. 24–25.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Мельцова А. Ж., Гриценко В. В., Орловский П. И. и др. Применение дермальных фибробластов в комплексном лечении больных трофическими язвами венозной этиологии // Вестн. хир. 2007. № 1. С. 72–77.</mixed-citation><mixed-citation xml:lang="en">Мельцова А. Ж., Гриценко В. В., Орловский П. И. и др. Применение дермальных фибробластов в комплексном лечении больных трофическими язвами венозной этиологии // Вестн. хир. 2007. № 1. С. 72–77.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Мельцова А. Ж., Сабельников В. В., Гриценко В. В. и др. Применение аллогенных дермальных фибробластов в комплексном лечении трофических язв венозной этиологии // Стационарозамещающие технологии. Амбулаторная хирургия. 2005. № 3. С. 34–36.</mixed-citation><mixed-citation xml:lang="en">Мельцова А. Ж., Сабельников В. В., Гриценко В. В. и др. Применение аллогенных дермальных фибробластов в комплексном лечении трофических язв венозной этиологии // Стационарозамещающие технологии. Амбулаторная хирургия. 2005. № 3. С. 34–36.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Dwarakanath A. D., Yu L. G., Brookes C. et al. Sticky neutrophils, pathergic arthritis, and response to heparin in pyoderma gangrenosum complicating ulcerative colitis // Gut. 1995. Vol. 37, № 4. P. 585–588.</mixed-citation><mixed-citation xml:lang="en">Dwarakanath A. D., Yu L. G., Brookes C. et al. Sticky neutrophils, pathergic arthritis, and response to heparin in pyoderma gangrenosum complicating ulcerative colitis // Gut. 1995. Vol. 37, № 4. P. 585–588.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Hafner J., Kühne A., Trüeb R. M. Successful grafting with EpiDex in pyoderma gangrenosum // Dermatology. 2006. Vol. 212, № 3. P. 258–259.</mixed-citation><mixed-citation xml:lang="en">Hafner J., Kühne A., Trüeb R. M. Successful grafting with EpiDex in pyoderma gangrenosum // Dermatology. 2006. Vol. 212, № 3. P. 258–259.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Powell F. C., Schroeter A. L., Su W. P., Perry H. O. Pyoderma gangrenosum: a review of 86 patients // Q. J. Med. 1985. Vol. 55, № 217. P. 173–186.</mixed-citation><mixed-citation xml:lang="en">Powell F. C., Schroeter A. L., Su W. P., Perry H. O. Pyoderma gangrenosum: a review of 86 patients // Q. J. Med. 1985. Vol. 55, № 217. P. 173–186.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Powell F. C., Su W. P., Perry H. O. Pyoderma gangrenosum: Classification and management // J. Am. Acad. Dermatol. 1996. Vol. 34, № 3. P. 395–409.</mixed-citation><mixed-citation xml:lang="en">Powell F. C., Su W. P., Perry H. O. Pyoderma gangrenosum: Classification and management // J. Am. Acad. Dermatol. 1996. Vol. 34, № 3. P. 395–409.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Wollina U. Pyoderma gangrenosum — a review // Orphanet J. Rare Dis. 2007. Vol. 2. P. 19.</mixed-citation><mixed-citation xml:lang="en">Wollina U. Pyoderma gangrenosum — a review // Orphanet J. Rare Dis. 2007. Vol. 2. P. 19.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
