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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">grekov</journal-id><journal-title-group><journal-title xml:lang="ru">Вестник хирургии имени И.И. Грекова</journal-title><trans-title-group xml:lang="en"><trans-title>Grekov's Bulletin of Surgery</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">0042-4625</issn><publisher><publisher-name>Federal State Budgetary Educational Institution of Higher Education «Academician I.P. Pavlov First St. Petersburg State Medical University» of the Ministry of Healthcare of the Russion Federation, FSBEI HE I.P.Pavlov SPbSMU MOH Russia</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.24884/0042-4625-2012-171-6-019-021</article-id><article-id custom-type="elpub" pub-id-type="custom">grekov-781</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject></subject></subj-group></article-categories><title-group><article-title>ХИРУРГИЧЕСКОЕ ЛЕЧЕНИЕ РАКА ЛЁГКОГО, ОСЛОЖНЁННОГО ПЛЕВРАЛЬНЫМ ВЫПОТОМ</article-title><trans-title-group xml:lang="en"><trans-title>SURGICAL TREATMENT OF LUNG CANCER COMPLICATED BY PLEURAL EFFUSION</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Яицкий</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Yaitsky</surname><given-names>N. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Акопов</surname><given-names>А. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Akopov</surname><given-names>A. L.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Махмуд</surname><given-names>Р. .</given-names></name><name name-style="western" xml:lang="en"><surname>Makhmud</surname><given-names>R. .</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Егоров</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Egorov</surname><given-names>V. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дейнека</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Dejneka</surname><given-names>I. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чистяков</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Chistyakov</surname><given-names>I. V.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Санкт-Петербургский государственный медицинский университет им. акад. И. П. Павлова; СПбГУЗ «Покровская больница»</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2012</year></pub-date><pub-date pub-type="epub"><day>16</day><month>01</month><year>2018</year></pub-date><volume>171</volume><issue>6</issue><fpage>19</fpage><lpage>21</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Яицкий Н.А., Акопов А.Л., Махмуд Р..., Егоров В.И., Дейнека И.В., Чистяков И.В., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Яицкий Н.А., Акопов А.Л., Махмуд Р..., Егоров В.И., Дейнека И.В., Чистяков И.В.</copyright-holder><copyright-holder xml:lang="en">Yaitsky N.A., Akopov A.L., Makhmud R..., Egorov V.I., Dejneka I.V., Chistyakov I.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.vestnik-grekova.ru/jour/article/view/781">https://www.vestnik-grekova.ru/jour/article/view/781</self-uri><trans-abstract xml:lang="en"><p>The authors made a retrospective analysis of 51 patients with non-small-cell lung cancer with pleural effusion, not associated with tumor lesion of pleural leaves. Out of 51operated patients 45 (88%) proved to be resectable. Among 45 patients (20 pneumonectomies, 24 lobectomies and 1 bilobectomy) combined interventions were fulfilled in 15 patients. In 27 (60%) out of 45 patients there was an injury of mediastinal lymph nodes, in 13 (29%) — intrapulmonary and root nodes. Complicated course of the postoperative period was noted in 27% of patients, lethality was 2%. One year survival after resection was 86%, three and five year survival was 54% and 30% respectively. The indices of survival reliably depended on the degree of lymphogenic dissemination. The presence of pleural effusion can not be a reason for refusal to fulfill radical surgical intervention.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>немелкоклеточный рак легкого</kwd><kwd>плевральный выпот</kwd><kwd>хирургическое лечение</kwd><kwd>эксплоративные операции</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Порханов В. А. Видеоторакоскопические операции в диагностике и лечении заболеваний органов дыхания // Пробл. туберкулеза. 1997. № 6. С. 27–32.</mixed-citation><mixed-citation xml:lang="en">Порханов В. А. Видеоторакоскопические операции в диагностике и лечении заболеваний органов дыхания // Пробл. туберкулеза. 1997. № 6. С. 27–32.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Трахтенберг А. Х., Чиссов В. И. Клиническая онкопульмонология. М., 2000. С. 599.</mixed-citation><mixed-citation xml:lang="en">Трахтенберг А. Х., Чиссов В. И. Клиническая онкопульмонология. М., 2000. С. 599.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Яблонский П. К., Пищик В. Г. Видеоторакоскопия в современной торакальной клинике // Вестн. хир. 2003. № 1. С. 110–114.</mixed-citation><mixed-citation xml:lang="en">Яблонский П. К., Пищик В. Г. Видеоторакоскопия в современной торакальной клинике // Вестн. хир. 2003. № 1. С. 110–114.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Heffner J. E., Klein J. S. Recent advances in the diagnosis and management of malignant pleural effusions // Mayo Clin. Proc. 2008. Vol. 83. P. 235–250.</mixed-citation><mixed-citation xml:lang="en">Heffner J. E., Klein J. S. Recent advances in the diagnosis and management of malignant pleural effusions // Mayo Clin. Proc. 2008. Vol. 83. P. 235–250.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Hiyoshi H., Iwanami H., Narita K. et al. Assessment of surgery for primary lung cancer with dissemination or malignant effusion of pleura (T4 advanced lung cancer) // Kyobu Geka. 1997. Vol. 50. P. 120–122.</mixed-citation><mixed-citation xml:lang="en">Hiyoshi H., Iwanami H., Narita K. et al. Assessment of surgery for primary lung cancer with dissemination or malignant effusion of pleura (T4 advanced lung cancer) // Kyobu Geka. 1997. Vol. 50. P. 120–122.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Kotyza J., Havel D., Vrzalová J. et al. Diagnostic and prognostic significance of inflammatory markers in lung cancer-associated pleural effusions // Int. J. Biol. Markers. 2010. Vol. 25. P. 12–20.</mixed-citation><mixed-citation xml:lang="en">Kotyza J., Havel D., Vrzalová J. et al. Diagnostic and prognostic significance of inflammatory markers in lung cancer-associated pleural effusions // Int. J. Biol. Markers. 2010. Vol. 25. P. 12–20.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Kremer R., Best L. A., Savulescu D. et al. Pleural fluid analysis of lung cancer vs benign inflammatory disease patients // Br. J. Cancer. 2010. Vol. 102. P. 1180–1184.</mixed-citation><mixed-citation xml:lang="en">Kremer R., Best L. A., Savulescu D. et al. Pleural fluid analysis of lung cancer vs benign inflammatory disease patients // Br. J. Cancer. 2010. Vol. 102. P. 1180–1184.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Light R. W. Diagnostic principles in pleural disease // Eur. Respir. J. 1997. Vol. 10. P. 476–481.</mixed-citation><mixed-citation xml:lang="en">Light R. W. Diagnostic principles in pleural disease // Eur. Respir. J. 1997. Vol. 10. P. 476–481.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Light R. W. Tumor markers in undiagnosed pleural effusions // Chest. 2004. Vol. 126. P. 1721–1724.</mixed-citation><mixed-citation xml:lang="en">Light R. W. Tumor markers in undiagnosed pleural effusions // Chest. 2004. Vol. 126. P. 1721–1724.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Neragi-Miandoab S. Malignant pleural effusion, current and evolving approaches for its diagnosis and management // Lung Cancer. 2006. Vol. 54. P. 1–9.</mixed-citation><mixed-citation xml:lang="en">Neragi-Miandoab S. Malignant pleural effusion, current and evolving approaches for its diagnosis and management // Lung Cancer. 2006. Vol. 54. P. 1–9.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Rami-Porta R., Crowley J., Goldstraw P. The revised TNM lung cancer staging system for lung cancer // Ann. Thorac. Cardiovasc. Surg. 2009. Vol. 15. P. 4–9.</mixed-citation><mixed-citation xml:lang="en">Rami-Porta R., Crowley J., Goldstraw P. The revised TNM lung cancer staging system for lung cancer // Ann. Thorac. Cardiovasc. Surg. 2009. Vol. 15. P. 4–9.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Sakr L., Maldonado F., Greillier L. et al. Thoracoscopic assessment of pleural tumor burden in patients with malignant pleural effusion: prognostic and therapeutic implications // J. Thorac. Oncol. 2011. Vol. 6. P. 592–597.</mixed-citation><mixed-citation xml:lang="en">Sakr L., Maldonado F., Greillier L. et al. Thoracoscopic assessment of pleural tumor burden in patients with malignant pleural effusion: prognostic and therapeutic implications // J. Thorac. Oncol. 2011. Vol. 6. P. 592–597.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Yokoi K., Miyazawa N. Pleuropneumonectomy and postoperative adjuvant chemotherapy for carcinomatous pleuritis in primary lung cancer: a case report of long-term survival // Eur. J. Cardiothorac. Surg. 1996. Vol. 10. P. 141–143.</mixed-citation><mixed-citation xml:lang="en">Yokoi K., Miyazawa N. Pleuropneumonectomy and postoperative adjuvant chemotherapy for carcinomatous pleuritis in primary lung cancer: a case report of long-term survival // Eur. J. Cardiothorac. Surg. 1996. Vol. 10. P. 141–143.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
