ASSESSMENT OF EXPERIMENTAL AND CLINICAL EFFICACY OF IMMOBILIZED FORM OF CHLORHEXIDINE IN TREATMENT OF PURULENT WOUNDS
https://doi.org/10.24884/0042-4625-2016-175-1-42-47
Abstract
The authors made an analysis of the results of experimental course of wound process on 120 rats of Vistar line and clinical research of 58 patients with purulent wounds, which were treated by ointment of following composition: chlorhexidine bigluconate 0,5-30,0; methyluracil -2,0; polymethylsiloxane polyhydrate -70,0. The animals and people were divided into 2 statistically uniform groups. The control group had a local treatment of wound by the ointment «Levomekol’». The experimental group used the immobilized forms of chlorhexidine. Dynamics of wound process was studied by planimetric, bacteriological and cytological methods of research. Results of planimetric, bacteriological and cytological investigations proved the more expressed positive effect of purulent wound treatment using immobilized form of chlorhexidine bigluconate.
About the Authors
B. S. Sukovatykh
Kursk State Medical University
Russian Federation
Russian Federation
A. I. Bezhin
Kursk State Medical University
Russian Federation
Russian Federation
T. A. Pankrusheva
Kursk State Medical University
Russian Federation
Russian Federation
A. Yu. Grigor’Yan
Kursk State Medical University
Russian Federation
Russian Federation
A. V. Ivanov
Kursk State Medical University
Russian Federation
Russian Federation
L. V. Zhilyaeva
Kursk State Medical University
Russian Federation
Russian Federation
E. V. Kobzareva
Kursk State Medical University
Russian Federation
Russian Federation
E. G. Andryukhina
Kursk State Medical University
Russian Federation
Russian Federation
A. A. Dubonos
Kursk Municipal clinical hospital of emergency medicine
Russian Federation
Russian Federation
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Review
For citations:
Sukovatykh B.S., Bezhin A.I., Pankrusheva T.A., Grigor’Yan A.Yu., Ivanov A.V., Zhilyaeva L.V., Kobzareva E.V., Andryukhina E.G., Dubonos A.A. ASSESSMENT OF EXPERIMENTAL AND CLINICAL EFFICACY OF IMMOBILIZED FORM OF CHLORHEXIDINE IN TREATMENT OF PURULENT WOUNDS. Grekov's Bulletin of Surgery. 2016;175(1):42-47. (In Russ.) https://doi.org/10.24884/0042-4625-2016-175-1-42-47
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