Clinical diagnostic features and surgical outcomes of mesial temporal lobe epilepsy
https://doi.org/10.24884/0042-4625-2022-181-3-91-99
Abstract
Despite certain successes in the treatment of epilepsy, primarily associated with the active development of pharmacology, in 30% of cases, there is a resistant course, especially focal forms of temporal lobe epilepsy. Mesial temporal sclerosis (MTS) is one of the most common causes of drug-resistant epilepsy. Conservative treatment could help only in 90–92 % of cases. In other cases, surgical treatment is required for improving the quality of life of such patients. However, the percentage of surgical care for epilepsy remains low. Structured information on clinical signs, diagnostic techniques, approaches to surgical treatment and its outcomes should contribute to understanding the problem among specialists. Data on the effectiveness of operations in patients with drug-resistant epilepsy can help in timely hightechnology care for patients with mesial temporal lobe epilepsy.
About the Authors
O. P. SubbotinaRussian Federation
Subbotina Olga P., Assistant, Department of Neurosurgery and Neurology
7-9, University Embankment, Saint Petersburg, 199034
Competing Interests:
The authors declare no conflict of interest
L. M. Tibekina
Russian Federation
Tibekina Lyudmila M., Dr. of Sci. (Med.), Professor, Department of Neurosurgery and Neurology
Saint-Petersburg
Competing Interests:
The authors declare no conflict of interest
S. N. Tonyan
Russian Federation
Tonyan Samvel N., Resident, Department of Neurosurgery and Neurology
Saint-Petersburg
Competing Interests:
The authors declare no conflict of interest
References
1. Singh A., Trevick S. The Epidemiology of Global Epilepsy // Neurol Clin. 2016;34(4):837–847. Doi: 10.1016/j.ncl.2016.06.015. PMID: 27719996.
2.
3. Guekht A., Hauser W. A., Milchakova L. et al. The epidemiology of epilepsy in the Russian Federation // Epilepsy Res. 2010;92(2–3):209–18. Doi: 10.1016/j.eplepsyres.2010.09.011. PMID: 21035312.
4.
5. Engel J. Jr. Mesial temporal lobe epilepsy: what have we learned? // Neuroscientist. 2001;7(4):340–52. doi: 10.1177/107385840100700410. PMID: 11488399.
6.
7. Semah F., Picot M. C., Adam C. et al. Is the underlying cause of epilepsy a major prognostic factor for recurrence? // Neurology. 1998;51(5):1256– 62. Doi: 10.1212/wnl.51.5.1256. PMID: 9818842.
8.
9. Pascual M. R. Temporal lobe epilepsy: clinical semiology and neurophysiological studies // Semin Ultrasound CT MR. 2007;28(6):416–23. Doi: 10.1053/j.sult.2007.09.004. PMID: 18074998.
10.
11. Rolston J. D., Englot D. J., Knowlton R. C., Chang E. F. Rate and complications of adult epilepsy surgery in North America: Analysis of multiple databases // Epilepsy Res. 2016;124:55–62. Doi: 10.1016/j. eplepsyres.2016.05.001. PMID: 27259069; PMCID: PMC5260847.
12.
13. Kiernan J. A. Anatomy of the temporal lobe // Epilepsy Res Treat. 2012;2012:176157. Doi: 10.1155/2012/176157. PMID: 22934160; PMCID: PMC3420617.
14.
15. Diogo A. C., Soares J. G., Koulakov A., Albright T. D., Gattass R. Electrophysiological imaging of functional architecture in the cortical middle temporal visual area of Cebus apella monkey // J Neurosci. 2003;23(9):3881–98. Doi: 10.1523/JNEUROSCI.23-09-03881.2003. PMID: 12736358; PMCID: PMC6742200.
16.
17. Blümcke I., Coras R., Miyata H., Ozkara C. Defining clinico-neuropathological subtypes of mesial temporal lobe epilepsy with hippocampal sclerosis // Brain Pathol. 2012;22(3):402–11. Doi: 10.1111/j.1750- 3639.2012.00583.x.
18.
19. Blümcke I., Pauli E., Clusmann H. et al. A new clinico-pathological classification system for mesial temporal sclerosis // Acta Neuropathol. 2007;113(3):235–44. Doi: 10.1007/s00401-006-0187-0. PMID: 17221203.
20.
21. Blümcke I., Thom M., Aronica E. et al. International consensus classification of hippocampal sclerosis in temporal lobe epilepsy: a Task Force report from the ILAE Commission on Diagnostic Methods // Epilepsia. 2013;54(7):1315–29. Doi: 10.1111/epi.12220. PMID: 23692496.
22.
23. Fisher R. S., Cross J. H., French J. A. Et al. Operational classification of seizure types by the International League Against Epilepsy: Position Paper of the ILAE Commission for Classification and Terminology // Epilepsia. 2017;58(4):522–530. Doi: 10.1111/epi.13670. PMID: 28276060.
24.
25. Ye B. S., Cho Y. J., Jang S. H. et al. The localizing and lateralizing value of auras in lesional partial epilepsy patients // Yonsei Med J. 2012;53(3):477–85. Doi: 10.3349/ymj.2012.53.3.477. PMID: 22476989; PMCID: PMC3343447.
26.
27. Mani J. Video electroencephalogram telemetry in temporal lobe epilepsy // Ann Indian Acad Neurol. 2014;17(Suppl 1):45–49. Doi: 10.4103/0972- 2327.128653. PMID: 24791089; PMCID: PMC4001214.
28.
29. Guo X., Xu S., Wang G., Zhang Y., Guo L., Zhao B. Asymmetry of cerebral blood flow measured with three-dimensional pseudocontinuous arterial spin-labeling mr imaging in temporal lobe epilepsy with and without mesial temporal sclerosis // J Magn Reson Imaging. 2015;42(5):1386– 97. Doi: 10.1002/jmri.24920. PMID: 25884243.
30.
31. Lin K., Carrete H., Lin J. et al. Facial paresis in patients with mesial temporal sclerosis: clinical and quantitative MRI-based evidence of widespread disease // Epilepsia. 2007;48(8):1491–9. Doi: 10.1111/j.1528- 1167.2007.01076.x. PMID: 17433056.
32.
33. Duncan J. S. Imaging in the surgical treatment of epilepsy // Nat Rev Neurol. 2010;6(10):537–50. Doi: 10.1038/nrneurol.2010.131. PMID: 20842185.
34.
35. Stefanits H., Springer E., Pataraia E. et al. Seven-Tesla MRI of Hippocampal Sclerosis: An In Vivo Feasibility Study With Histological Correlations // Invest Radiol. 2017;52(11):666–671. Doi: 10.1097/ RLI.0000000000000388. PMID: 28538339.
36.
37. De Ciantis A., Barba C., Tassi L. et al. 7T MRI in focal epilepsy with unrevealing conventional field strength imaging // Epilepsia. 2016;57(3):445– 54. Doi: 10.1111/epi.13313. PMID: 26778405.
38.
39. Engel J. Jr, Thompson P. M. Going beyond hippocampocentricity in the concept of mesial temporal lobe epilepsy // Epilepsia. 2012;53(1):220–3. Doi: 10.1111/j.1528-1167.2011.03366.x. PMID: 22221162.
40.
41. Javan R., Schickel M., Zhao Y. et al. Using 3D-Printed Mesh-Like Brain Cortex with Deep Structures for Planning Intracranial EEG Electrode Placement // J Digit Imaging. 2020;33(2):324–333. Doi: 10.1007/s10278- 019-00275-3. PMID: 31512018.
42.
43. Najm I. M. Mapping brain networks in patients with focal epilepsy // Lancet Neurol. 2018;17(4):295–297. Doi: 10.1016/S1474-4422(18)30090-5. PMID: 29553374.
44.
45. Khachatryan V. A., Mamatkhanov M. R., Lebedev K. E. Invasive EEG-monitoring for surgical treatment of epilepsy in children // The Russian Neurosurgical Journal named after prof. A. L. Polenov. 2014;4(4): 22–27. (In Russ.).
46.
47. Denisova N. P., Rogov D. Yu., Halepa A. A. Surgical treatment of mesial temporal epilepsy applying intraoperative and chronic electrocorticography (ECoG) // Russian journal of neurosurgery. 2017;(3):20–26. (In Russ.).
48.
49. Hutchison R. M., Womelsdorf T., Allen E. A. et al. Dynamic functional connectivity: promise, issues, and interpretations // Neuroimage. 2013;80:360–78. Doi: 10.1016/j.neuroimage.2013.05.079. PMID: 23707587; PMCID: PMC3807588.
50.
51. Ryvlin P., Cross J. H., Rheims S. Epilepsy surgery in children and adults // Lancet Neurol. 2014;13(11):1114–1126. Doi: 10.1016/S1474- 4422(14)70156-5. PMID: 25316018.
52.
53. Schramm J., Lehmann T. N., Zentner J. et al. Randomized controlled trial of 2.5-cm versus 3.5-cm mesial temporal resection in temporal lobe epilepsy – Part 1: intent-to-treat analysis // Acta Neurochir (Wien). 2011;153(2):209–19. Doi: 10.1007/s00701-010-0900-6. PMID: 21170558.
54.
55. Boon P., De Cock E., Mertens A., Trinka E. Neurostimulation for drugresistant epilepsy: a systematic review of clinical evidence for efficacy, safety, contraindications and predictors for response // Curr Opin Neurol. 2018;31(2):198–210. Doi: 10.1097/WCO.0000000000000534. PMID: 29493559.
56.
57. Engel J. Jr. Update on surgical treatment of the epilepsies. Summary of the Second International Palm Desert Conference on the Surgical Treatment of the Epilepsies (1992) // Neurology. 1993;43(8):1612–7. Doi: 10.1212/wnl.43.8.1612. PMID: 8102482.
58.
59. Wieser H. G., Blume W. T., Fish D. Commission on Neurosurgery of the International League Against Epilepsy (ILAE). ILAE Commission Report. Proposal for a new classification of outcome with respect to epileptic seizures following epilepsy surgery // Epilepsia. 2001;42(2):282–6. PMID: 11240604.
60.
61. Mathon B., Bielle F., Samson S. et al. Predictive factors of long-term outcomes of surgery for mesial temporal lobe epilepsy associated with hippocampal sclerosis // Epilepsia. 2017;58(8):1473–1485. Doi: 10.1111/ epi.13831. PMID: 28656696.
62.
63. Mathon B., Bédos U. L, Adam C. et al. Surgical treatment for mesial temporal lobe epilepsy associated with hippocampal sclerosis // Rev Neurol (Paris). 2015;171(3):315–25. Doi: 10.1016/j.neurol.2015.01.561. PMID: 25746582.
64.
65. Krylov V. V., Gekht1 A. B., Trifonov I. S. et al. Outcomes of surgical treatment of patients with pharmacoresistant epilepsy // Journal of Neurology and Psychiatry named after S. S. Korsakov. 2016;116(9–2):13–18. (In Russ.). Doi:jnevro20161169213-18.
66.
67. Kasumov V. R., Bersnev V. R., Kasumov R. D. Transcortical amygdalohippocampectomy to treat drug-resistant epilepsy // Creative surgery and oncology. 2011;(1):62–65. (In Russ.).
68.
69. Schmeiser B., Daniel M., Kogias E. et al. Visual field defects following different resective procedures for mesiotemporal lobe epilepsy // Epilepsy Behav. 2017;76:39–45. Doi: 10.1016/j.yebeh.2017.08.037. PMID: 28954709.
70.
71. Feng E. S., Sui C. B., Wang T. X., Sun G. L. Stereotactic radiosurgery for the treatment of mesial temporal lobe epilepsy // Acta Neurol Scand. 2016;134(6):442–451. Doi: 10.1111/ane.12562. PMID: 26846702.
72.
73. Krylov V. V., Rak V. A., Tokarev A. S. et al. Stereotactic Radiosurgery in the Complex Treatment of Patients With Epilepsy Associated With Various Structural Brain Lesions // Emergency Medical Care : Russian Sklifosovsky Journal. 2021;10(1):73–82. Doi: 10.23934/2223-9022- 2021-10-1-73-82.
74.
75. Kasumov V. R. Early and late results of surgical treatment of multifocal epilepsy // Bulletin of Siberian Medicine. 2009;8(1(2)):42–45. (In Russ.). Doi:10.20538/1682-0363-2009-1(2)-42-45.
76.
77. McGonigal A., Sahgal A., De Salles A. et al. Radiosurgery for epilepsy: Systematic review and International Stereotactic Radiosurgery Society (ISRS) practice guideline // Epilepsy Res. 2017;137:123–131. Doi: 10.1016/j.eplepsyres.2017.08.016. PMID: 28939289.
78.
79. Bezchlibnyk Y. B., Willie J. T., Gross R. E. A neurosurgeon`s view: Laser interstitial thermal therapy of mesial temporal lobe structures // Epilepsy Res. 2018;142:135–139. Doi: 10.1016/j.eplepsyres.2017.10.015. PMID: 29111296.
80.
81. King-Stephens D. What Is the Best Target for Ablation of Mesial Temporal Lobe Epilepsy? // Epilepsy Curr. 2019;19(5):313–315. Doi: 10.1177/1535759719868460. PMID: 31409148; PMCID: PMC6864567.
82.
83. Kang J. Y., Wu C., Tracy J. et al. Laser interstitial thermal therapy for medically intractable mesial temporal lobe epilepsy // Epilepsia. 2016;57(2):325–34. Doi: 10.1111/epi.13284. PMID: 26697969.
84.
85. Bourdillon P., Cucherat M., Isnard J. et al. Stereo-electroencephalographyguided radiofrequency thermocoagulation in patients with focal epilepsy: A systematic review and meta-analysis // Epilepsia. 2018;59(12):2296– 2304. Doi: 10.1111/epi.14584. PMID: 30345535.
86.
87. Toth M., Papp K. S., Gede N. et al. Surgical outcomes related to invasive EEG monitoring with subdural grids or depth electrodes in adults: A systematic review and meta-analysis // Seizure. 2019;70:12–19. Doi: 10.1016/j.seizure.2019.06.022.
88.
89. Willems L. M., Reif P. S., Spyrantis A. et al. Invasive EEG-electrodes in presurgical evaluation of epilepsies: Systematic analysis of implantation-, video-EEG-monitoring- and explantation-related complications, and review of literature // Epilepsy Behav. 2019;91:30–37. Doi: 10.1016/j. yebeh.2018.05.012. PMID: 29907526.
Supplementary files
Review
For citations:
Subbotina O.P., Tibekina L.M., Tonyan S.N. Clinical diagnostic features and surgical outcomes of mesial temporal lobe epilepsy. Grekov's Bulletin of Surgery. 2022;181(3):91-99. (In Russ.) https://doi.org/10.24884/0042-4625-2022-181-3-91-99