Preview

Grekov's Bulletin of Surgery

Advanced search

Angiographic index of myocardial viability in patients with different duration of occlusive coronary lesion

https://doi.org/10.24884/0042-4625-2022-181-1-27-32

Abstract

INTRODUCTION. Evaluation of myocardial viability in chronic coronary occlusion determines the feasibility of revascularization of this zone.

The OBJECTIVE was to evaluate the significance of the angiographic index in determining the viability of the myocardium at various times after occlusion of the coronary artery.

METHODS AND MATERIALS. 156 patients with coronary artery disease (CAD) with chronic coronary occlusion according to coronary angiography (CG) were examined and treated during the period from 2012 to 2021. All patients underwent endovascular recanalization of chronic coronary occlusion. All patients were divided into 4 groups depending on the time of coronary occlusion (up to 3 months, 3-6 months, 6-9 months, more than 9 months) The results of recanalization were compared to the preoperative evaluation of myocardial viability based on the volume of collateral blood flow (Renrop score).

RESULTS. The angiographic index of non-viable myocardium was highly specific from the first months in all observation groups (77, 94, 97, 97.5 %), however, its sensitivity had diagnostic value only in patients with occlusion duration of more than 6 months (80 % or more).

CONCLUSION. The diagnostic value (sensitivity and specificity) of detecting non-viable myocardium based on retrograde collateral blood flow is significant for occlusion duration of more than 6 months. Refusal of revascularization based on the absence of retrograde blood flow during the first 6 months after coronary occlusion is not correct.

About the Authors

N. A. Yaitskiy
Pavlov University
Russian Federation

Nikolay A. Yaitskiy - Dr. of Sci. (Med.), Professor, Academician of the Russian Academy of Sciences, Head of the Department of Hospital Surgery with Clinic, Pavlov University.

Saint Petersburg.


Competing Interests:

The authors declare no conflict of interest.



O. G. Zverev
Pavlov University; Saint Petersburg Research Institute of Phthisiopulmonology
Russian Federation

Oleg G. Zverev - Dr. of Sci. (Med.), Professor of the Department of Hospital Surgery with Clinic, Pavlov University; Head of the Department of X-ray Surgical Methods of Diagnosis and Treatment, Saint Petersburg Research Institute of Phthisiopulmonology.

6-8, L'va Tolstogo str., Saint Petersburg, 197022.


Competing Interests:

The authors declare no conflict of interest.



A. V. Voynov
Pavlov University; Saint Petersburg Research Institute of Phthisiopulmonology
Russian Federation

Alexey V. Voynov - Assistant of the Department of Hospital Surgery with Clinic, Pavlov University, Doctor of the Department of X-ray Surgical Methods of Diagnosis and Treatment, Saint Petersburg Research Institute of Phthisiopulmonology.

6-8, L'va Tolstogo str., Saint Petersburg, 197022.


Competing Interests:

The authors declare no conflict of interest.



S. M. Lazarev
Pavlov University
Russian Federation

Sergey M. Lazarev - Dr. Sci. (Med), Professor, Department of Hospital Surgery with Clinic, Pavlov University.

Saint Petersburg.


Competing Interests:

The authors declare no conflict of interest.



References

1. Fuster V., Frye R. L., Kennedy M. A., Connolly D. C., Mankin H. T. The role of collateral circulation in the various coronary syndromes // Circulation. 1979;(59):1137-1144.

2. Greenspan M., Iskandrian A. S., Segal B. L., Kimbiris D., Bemis C. E. Complete occlusion of the left main coronary artery // Am Heart J. 1979;(98):83-86.

3. Hamby R. I., Aintablian A., Schwaltz A. Reappraisal of the functional significance of the coronary collateral circulation // Am J Cardiol 1976;(38):304-309.

4. Fujita M., Sasayama S., Ohno A., Yamanishi K., Hirai T. Functional significance of coronary collateral perfusion in preserving myocardial integrity // Clin Cardiol. 1987;(10):394-398.

5. Yerushalmy J. Statistical problems in assessing methods of medical diagnosis, with special reference to X-ray techniques // Public Health Rep. 1947;(62):1432-1449.

6. Allman K. C., Shaw L. J., Hachamovitch R., Udelson J. E. Myocardial viability testing and impact of revascularization on prognosis in patients with coronary artery disease and left ventricular dysfunction: A metaanalysis // J Am Coll Cardiol 2002;(39):1151-1158

7. Yap J., Lim F. Y., Gao F., Wang S. Z., Low S. C. S., Le T. T., Tan R. S. Effect of Myocardial Viability Assessed by Cardiac Magnetic Resonance on Survival in Patients With Severe Left Ventricular Dysfunction // Circ Rep. 2020;(6):306-313.

8. Beanlands R. S., Nichol G., Huszti E., Humen D., Racine N., Freeman M., Gulenchyn K. Y., Garrard L., deKemp R., Guo A., Ruddy T. D., Benard F., Lamy A., Iwanochko R. M. PARR-2 Investigators. F-18-fluorodeoxyglucose positron emission tomography imaging-assisted management of patients with severe left ventricular dysfunction and suspected coronary disease: a randomized, controlled trial (PARR-2) // J Am Coll Cardiol. 2007;(50):2002-2012.

9. Bonow R. O., Maurer G., Lee K. L., Holly T. A., Binkley P. F., Desvigne-Nickens P., Drozdz J., Farsky P. S., Feldman A. M., Doenst T., Michler R. E., Berman D. S., Nicolau J. C., Pellikka P. A., Wrobel K., Alotti N., Asch F. M., Favaloro L. E., She L., Velazquez E. J., Jones R. H., Panza J. A. STICH Trial Investigators. Myocardial viability and survival in ischemic left ventricular dysfunction // N Engl J Med. 2011;(364):1617-1625.

10. Cuocolo A., Petretta M., Nicolai E. et al. Successful coronary revascularization improves prognosis in patients with previous myocardial infarction and evidence of viable myocardium at thallium-201 imaging // Eur J Nucl Med. 1998;(25):60-68.

11. Pasquet A., Robert A., D'Hondt A. M., Dion R., Melin J. A., Vanoverschel-de J. L. Prognostic value of myocardial ischemia and viability in patients with chronic left ventricular ischemic dysfunction // Circulation. 1999;(100):141-148.

12. Podio V., Spinnler M. T., Bertuccio G., Carbonero C., Pelosi E., Bisi G. Prognosis of hibernating myocardium is independent of recovery of function: evidence from a routine based follow-up study // Nucl Med Commun. 2002;(23):933-942

13. Sicari R., Picano E., Cortigiani L. et al. Prognostic value of myocardial viability recognized by low-dose dobutamine echocardiography in chronic ischemic left ventricular dysfunction // Am J Cardiol. 2003; (92):1263-1266.

14. Liao L., Cabell C. H., Jollis J. G. et al. Usefulness of myocardial viability or ischemia in predicting long-term survival for patients with severe left ventricular dysfunction undergoing revascularization // Am J Cardiol. 2004;(93):1275-1279.

15. Sawada S. G., Dasgupta S., Nguyen J. et al. Effect of revascularization on long-term survival in patients with ischemic left ventricular dysfunction and a wide range of viability // Am J Cardiol. 2010;(106):187-192.

16. Schinkel A. F. L., Bax J. J., Poldermans D., Elhendy A., Ferrari R., Rahimtoola S. H. Hibernating myocardium: diagnosis and patient outcomes // Curr Probl Cardiol. 2007;(32):375-410.

17. Camici P. G., Prasad S. K., Rimoldi O. E. Stunning, hibernation, and assessment of myocardial viability // Circulation. 2OO8;(117):103—114.


Supplementary files

Review

For citations:


Yaitskiy N.A., Zverev O.G., Voynov A.V., Lazarev S.M. Angiographic index of myocardial viability in patients with different duration of occlusive coronary lesion. Grekov's Bulletin of Surgery. 2022;181(1):27-32. (In Russ.) https://doi.org/10.24884/0042-4625-2022-181-1-27-32

Views: 359


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 0042-4625 (Print)
ISSN 2686-7370 (Online)