РЕЗУЛЬТАТЫ ХИРУРГИЧЕСКОГО ЛЕЧЕНИЯ РАКА РОТОВОЙ ПОЛОСТИ T1-2N0M0
Аннотация
The article shows the results of treatment of 20 patients (aged from 46 to 85 years old) with early oral cavity squamous cell carcinoma at the period from April 2009 to January 2011. The surgery included the resection of primary tumor and neck dissection in all the patients. The primary tumor was removed by mouth access in 10 patients and combined method was used in 10 cases. The selective neck dissection was carried out in 22 cases. The oral cavity wounds were closed primarily by local flaps in 10 patients, some small residual defects were left open in 3 cases. The reconstructions with remote skin-muscular infra-hyoid flap were performed in 7 patients. The free revascularized radial skin-fascia flap was used in 3 cases. A follow-up period was from 24 to 44 months. The primary local regional control consisted of 85% in given group of patients. The rate of recurrence of the second primary metachronous tumor was 15%. Tumors were located in the oral cavity. Overall 3-year survival was 90% (18 out of 20 patients).
Об авторах
Андрей Викторович Карпенко
Ленинградский областной онкологический диспансер
Россия
Россия
Рамиль Рустамович Сибгатуллин
Ленинградский областной онкологический диспансер
Россия
Россия
Елена Николаевна Белова
Ленинградский областной онкологический диспансер
Россия
Россия
Александр Александрович Бойко
Ленинградский областной онкологический диспансер
Россия
Россия
Валерий Геннадьевич Золотых
Ленинградский областной онкологический диспансер
Россия
Россия
Ласло Дюлович Роман
Ленинградский областной онкологический диспансер
Россия
Россия
Список литературы
1. Роман Ласло Дюлович
2. Клинические рекомендации по лечению опухолей головы и шеи Общенациональной онкологической сети (США). М.: ООО «АБВ-пресс», 2011. OR2.
3. Кропотов М. А. Общие принципы лечения больных первичным раком головы и шеи // Практ. онкол. 2003. № 1. C. 1-8.
4. Alvi A., Johnson J. Extracapsular spread in the clinically negative neck (N0): implication and outcome // Otolaryngol. Head Neck Surg. 1996. Vol. 114. P. 65-70.
5. Barry C., Katre C., Papa E. et al. De-escalation of surgery for early oral cancer - is it oncologically safe? // Br. J. Oral Maxillofac. Surg. 2013. Vol. 51. P. 30-36.
6. Beeken L., Calman F. A return to “normal” eating after curative treatment of oral cancer. What are long term prospects? // Eur. J. Cancer. 1994. Vol. 30B. P. 387-392.
7. Bundgaard T., Tandrup O., Elbrond O. A functional evaluation of patients treated for oral cancer. A prospective study // Int. J. Oral Maxillofac. Surg. 1993. Vol. 22. P. 28-34.
8. Chepeha D., Teknos T., Shargorodsky J. et al. Rectangle tongue template for reconstruction of the hemiglossectomy defect // Arch. Otolaryngol. Head Neck Surg. 2008. Vol. 134. P. 993-998.
9. Dunne A., Folz B., Kuropkat C., Werner J. Extent of surgical intervention in case of N0 neck in head and neck cancer patient: an analysis of data collection of 39 hospitals // Eur. Arch. Otorhinilaryngol. 2004. Vol. 261. P. 295-303.
10. Dwivedi R., St.Rose S., Chisholm E. et al. Evaluation of factors affecting post-treatment quality of life in oral and oropharyngeal cancer patients primarily treated with curative surgery: an exploratory study // Eur. Arch. Otorhinilaryngol. 2012. Vol. 269. P. 591-599.
11. Evans P., Montgomery P., Gullane P. Head and neck oncology / London., New York / ed. Informa Healthcare, 2003. P. 279-329.
12. Finlay P., Dawson F., Robertson A. et al. An evaluation of functional outcome after surgery and radiotherapy for intraoral cancer // Br. J. Oral Maxillofac. Surg. 1992. Vol. 30. P. 14-17.
13. Franceschi D., Gupta R., Spiro R. et al. Improved survival in the treatment of squamous cell carcinoma of the oral tongue // Am. J. Surg. 1993. Vol. 166. P. 360-365.
14. Genden E., Ferlito A., Silver C. et al. Contemporary management of the oral cavity cancer // Eur. Arch. Otorhinolaryngol. 2010. Vol. 267. P. 1001-1017.
15. Hicks W., Loree T., Garcia R. et al. Squamous cell carcinoma of the floor of mouth: a 20-year review // Head Neck. 1997. Vol. 19. P. 400-405.
16. Mighrani H., Myer G., Hans S. et al. The musculocutaneous infra-hyoid flap: surgical key points // Eur. Arch. Otolaryngol. Head Neck Surg. 2012. Vol. 269. P. 1213-1217.
17. Pillsburry H., Clark M. A rationale for the therapy of N0 neck // Laryngoscope. 1997. Vol. 107. P. 1294-1300.
18. Prince S., Bailey B. Squamous carcinoma of the tongue: review // Br. J. Oral Maxillofac. Surg. 1999. Vol. 37. P. 164-174.
19. Rogers S., Scott J., Chacrabati A. et al. The patient, account of outcome following primary surgery for oral and oropharyngeal cancer using a “quality of life” questionnaire // Eur. J. Cancer Care. 2008. Vol. 17. P. 182-188.
20. Shah J. Cancer of the head and neck. Toronto: BC Decker, 2001. P. 100-126.
21. Stuckensen T., Kovasc A., Adams S. et al. Staging of the neck in patients with oral cavity squamous cell carcinomas: a prospective comparison of PET, ultrasound, CT and MRI // J. Craniomaxillfac. Surg. 2000. Vol. 28. P. 319-324.
22. Wernig J., Heard D., Pagano C. et al. Elective management of clinically negative neck by otolaryngologists in patients with oral tongue cancer // Arch. Otolaryngol. Head Neck Surg. 2003. Vol. 129. P. 203-208.
23. Wolfensberger M., Zbaeren P., Dulguerov P. et al. Surgical treatment of early oral carcinoma - results of a prospective controlled multicenter study // Head Neck. 2001. Vol. 23. P. 525-530.
Рецензия
Для цитирования:
Карпенко А.В., Сибгатуллин Р.Р., Белова Е.Н., Бойко А.А., Золотых В.Г., Роман Л.Д. РЕЗУЛЬТАТЫ ХИРУРГИЧЕСКОГО ЛЕЧЕНИЯ РАКА РОТОВОЙ ПОЛОСТИ T1-2N0M0. Вестник хирургии имени И.И. Грекова. 2014;173(2):52-56. https://doi.org/10.24884/0042-4625-2014-173-2-52-56
For citation:
Karpenko A.V., Sibgatullin R.R., Belova E.N., Boiko A.A., Zolotykh V.G., Roman L.D. RESULTS OF SURGICAL TREATMENT OF ORAL CAVITY CANCER T1-2N0M0. Grekov's Bulletin of Surgery. 2014;173(2):52-56. (In Russ.) https://doi.org/10.24884/0042-4625-2014-173-2-52-56
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