SURGICAL TREATMENT OF MULTIPLE ISOLATED INTRAPULMONARY METASTASES
https://doi.org/10.24884/0042-4625-2014-173-4-25-30
Abstract
An analysis of treatment results was made in 226 patients with multiple isolated intrapulmonary metastases of solid tumors. It appears that surgical removal of metastases was possible in patients with satisfactory functional resources and accurate evaluation in order to validate the indications for surgery. The operation shouldn’t result in considerable reduction of quality of life and didn’t prevent using other methods of treatment such as medicamental and radiation therapy. The indications to surgical intervention have to be set as individual in consideration of the number of metastases and potential of the patient to undergo the surgery.
About the Authors
A. V. Reshetov
I. I. Mechnikov North-Western State Medical University, Saint-Petersburg
Russian Federation
Russian Federation
A. V. El’Kin
I. I. Mechnikov North-Western State Medical University, Saint-Petersburg
Russian Federation
Russian Federation
G. V. Nikolaev
V.A. Almazov Federal centre of the heart, blood and endocrinology
Russian Federation
Russian Federation
O. E. Kakysheva
I. I. Mechnikov North-Western State Medical University, Saint-Petersburg
Russian Federation
Russian Federation
D. I. Kovalenko
I. I. Mechnikov North-Western State Medical University, Saint-Petersburg
Russian Federation
Russian Federation
References
1. Пикин О. В. Метастатические опухоли лёгких (возможности диагностики и место хирургического метода в лечении): Дис. … д-ра мед. наук. М., 2006. 228 с.
2. Чиссов В. И., Трахтенберг А. Х., Пикин О. В., Паршин В. Д. Метастатические опухоли лёгких. М.: ГЭОТАР-Медиа, 2009. 159 с.
3. Aberg T. Selection mechanisms as major determinants of survival after pulmonary metastasectomy // Ann. Thorac. Surg. 1997. Vol. 63, № 3. P. 611-612.
4. Aberg T., Malmberg K. A., Nilsson B., Nou E. The effect of metastasectomy: fact or fiction? // Ann. Thorac. Surg. 1980. Vol. 30, № 4. P. 378-384.
5. Assouad J., Petkova B., Berna P. et al. Renal cell carcinoma lung metastases surgery: pathologic findings and prognostic factors // Ann. Thorac. Surg. 2007. Vol. 84, № 4. P. 1114-1120.
6. Dedirmenci M., Karaca B., Gorumlu G. et al. Efficacy and safety of bevacizumab plus capecitabine and irinotecan regimen for metastatic colorectal cancer // Med. Oncol. 2010. Vol. 27, № 3. P. 585-591.
7. Kim S., Ott H. C., Wright C. D. et al. Pulmonary resection of metastatic sarcoma: prognostic factors associated with improved outcomes // Ann. Thorc. Surg. 2011. Vol. 92, № 5. P. 1780-1786.
8. Kycler W., Laski P. Surgical approach to pulmonary metastases from breast cancer // Breast J. 2012. Vol. 18, № 1. P. 52-57.
9. Margaritora S., Proziella V., D Andrilli A. et al. Pulmonary metastases: can accurate radiological evaluation avoid thoracotomic approach? // Eur. J. Cardiothorac. Surg. 2002. Vol. 21, № 6. P. 1111-1114.
10. Monterio A., Arce N., Bernardo J. et al. Surgical resection of lung metastases from epithelial tumors // Ann. Thorac. Surg. 2004. Vol. 77, № 2. P. 431-437.
11. Rena O., Papalia E., Oliaro A. et al. // Pulmonary metastases from epithelial tumours: late results of surgical treatment // Eur. J. Cardiotorac. Surg. 2006. Vol. 30, № 2. P. 217-222.
12. Siva S., MacManus M., Ball D. Stereotactic radiotherapy for pulmonary oligometastases: a systematic review // J. Thorac. Oncol. 2010. Vol. 5, № 7. P. 1091-1099.
13. Tonnies M., Kollmeier J., Bauer T.T. et al. Curative surgical treatment options for patients with non-small cell lung cancer (NSCLC) and solitary pulmonary metastasis // Pneumologie. 2012. Vol. 66, № 4. P. 218-223.
14. Van Cutsem E., Rivera F., Berry S. et al. Safety and efficacy of first-line bevacizumab with FOLFOX, XELOX, FOLFIRI and fluoropyrimidines in metastatic colorectal cancer: the BEAT study // Ann. Oncol. 2009. Vol. 20, № 11. P. 1842-1847.
15. Vodicka J., Spidlen V., Simanek V. et al. Surgical therapy of pulmonary metastases of colorectal cancer ten-year results // Rozhl. Chir. 2012. Vol. 91, № 2. P. 81-86.
16. Weiser M. R., Downey R. J., Leung D. H., Brennan M. F. Repeat resection of pulmonary metastases in patients with soft-tissue sarcoma // J. Am. Coll. Surg. 2000. Vol. 191, № 2. P. 184-190.
17. Younes R. N., Gross J. L., Deheinzelin D. Surgical resection of unilateral lung metastases: is bilateral thoracotomy necessary? // World J. Surg. 2002. Vol. 26, № 9. P. 1112-1116.
Review
For citations:
Reshetov A.V., El’Kin A.V., Nikolaev G.V., Kakysheva O.E., Kovalenko D.I. SURGICAL TREATMENT OF MULTIPLE ISOLATED INTRAPULMONARY METASTASES. Grekov's Bulletin of Surgery. 2014;173(4):25-30. (In Russ.) https://doi.org/10.24884/0042-4625-2014-173-4-25-30
Views:
359
Email this article 