Preview

Grekov's Bulletin of Surgery

Advanced search

CLINICAL AND MORPHOLOGICAL ASPECTS OF THE APPLICATION OF PLATELET GROWTH FACTORS IN PATIENTS WITH PILONIDAL CYST WITH ABSCESS

https://doi.org/10.24884/0042-4625-2018-177-2-52-56

Abstract

OBJECTIVE. The objective of this study is to investigate the surgical management of pilonidal cyst with abscess and to improve short-term and long-term outcomes.

MATERIAL AND METHODS. The initial sample consisted of 353 patients operated for pilonidal cyst with abscess. The first group included 105 patients, receiving treatment with the excision of pilonidal cyst and the suturing in staggered rows. The second group consisted of 136 patients with the excision of pilonidal cyst using a unique patented technique. The third group of 112 patients underwent an identical operation to that of the second group, but with additional platelet growth factors (PGF) to improve the wound healing.

RESULTS. The current study found that in comparison to the traditional technique, the optimal surgical treatment of pilonidal cyst with abscess was the original one-staged surgical technique, based on an economical excision, which led to an improvement in sickness leave of up to 27 days and in long-term outcomes (2 % of long-term complications). Another important finding was that the application of platelet growth factors (PGF) in the complex treatment of patients with pilonidal cyst with abscesses reduces the recovery time by up to 21 days and resulted in 30 % lower postoperative pain scores (Visual Analog Scale for Pain).

CONCLUSION. In general, this finding shows that the original one-stage excision of pilonidal cyst with abscess with the application of PGF and with no suturing reduces disability time without increasing the number of early or late postoperative complications.  

About the Authors

E. E. Achkasov
Federal State Autonomous Educational Institution of Higher Education «I. M. Sechenov First Moscow State Medical University» of the Ministry of Healthcare of the Russian Federation
Russian Federation
Moscow


A. Ya. Solomka
State Budgetary Healthcare Institution «City Clinical Hospital № 24 of the Moscow Healthcare Department»
Russian Federation
Moscow


A. A. Ulyanov
«Central Out-patient Hospital of Literature Fund», Closed Joint Stock Company
Russian Federation
Moscow


Е. N. Bezuglov
Federal State Autonomous Educational Institution of Higher Education «I. M. Sechenov First Moscow State Medical University» of the Ministry of Healthcare of the Russian Federation
Russian Federation
Moscow


E. V. Orekhova
State Budgetary Healthcare Institution of the city of Moscow «City Clinical Hospital № 67 named after L.A. Vorobokhov» of the Moscow Healthcare Department
Russian Federation
Moscow


T. M. Zharikova
Federal State Autonomous Educational Institution of Higher Education «I. M. Sechenov First Moscow State Medical University» of the Ministry of Healthcare of the Russian Federation
Russian Federation
Moscow


References

1. Khamis A., McCallum I., King P. M. Healing by primary versus secondary intention after surgical treatment for pilonidal sinus // Cochrane Database Syst Rev. 2010. Vol. 20. Р. 6213.

2. Nechay I. A., Maltsev N. P., Afanasyeva E. P. «Zakrytye» metodiki v lechenii pilonidalnoy bolezni. Koloproktologiya nauchno-prakticheskiy meditsinskiy zhurnal // Materials of the International United Congress of the Coloproctology Association of Russia and the First Regional Masterclass ESCP/ECCO (sbornik tezisov). Moscow, 2015. P. 36.

3. Mentes O., Bagci M., Bilgin T. Management of pilonidal sinus disease with oblique excision and primary closure : results of 493 patients // Dis. Colon. Rectum. 2006. Vol. 49. Р. 104–108.

4. Vorobey A. V., Rizhma M. I., Denisenko V. L. Optimizatsiya lecheniya epitelialnykh kopchikovykh khodov, oslozhnennykh abstsessom // Problemy koloproktologii. 2002. Vyp. 18. P. 48–51.

5. Alekperov E. E., Bolkvadze E. E., Mudarisov R. R., Musin A. I. Sravnitelnaya otsenka metodov khirurgicheskogo lecheniya ostrogo vospaleniya epitelialnogo kopchikovogo khoda // Koloproktologiya nauchno-prakticheskiy meditsinskiy zhurnal. Materials of the International United Congress of the Coloproctology Association of Russia and the First Regional Masterclass ESCP/ECCO (sbornik tezisov). Moscow, 2015. P. 14.

6. Pomazkin V. I. Ispolzovanie modifitsirovannoy plastiki po Limbergu pri lechenii epitelialnogo kopchikovogo khoda // Materials of the International United Congress of the Coloproctology Association of Russia and the First Regional Masterclass ESCP/ECCO (sbornik tezisov). Moscow, 2015. P. 39.

7. Данилов Т. З. Лечение эпителиального копчикового хода // Пробл. колопроктол. Вып. 17. М., 2000. С. 63. [Danilov T. Z. Lechenie epitelialnogo kopchikovogo khoda. Problemy koloproktologii. 2000. Vyp. 17. P. 63].

8. Murtazaev T. S. Kliniko-anatomicheskoe obosnovanie vybora metoda khirurgicheskogo lecheniya epitelialnogo kopchikovogo khoda i ego oslozhneniy: avtoref. dis. kand. med. nauk. Stavropol, 2008. 24 p..

9. Valieva E. K. Optimizatsiya khirurgicheskikh metodov lecheniya bolnykh s nagnoivshimsya epitelialnym kopchikovym khodom: avtoref. dis. kand. med. nauk. Ufa, 2006. P. 24.

10. Bykov I. M., Basov A. A., Malyshko V. V. i dr. Dinamika pokazateley prooksidantno-antioksidantnoy sistemy v ranevom otdelyaemom i plazme krovi pri modelirovanii gnoynoy rany i ee lechenii apparatnym sposobom v zhidkoy faze // Byulleten eksperimentalnoy biologii i mediciny. 2017. Vol. 163, № 2. Р. 237–241.

11. Legonkova O. A., Ushakova T. A., Savchenkova I. P. i dr. Eksperimentalnoe issledovanie vliyaniya nanodispersnogo dioksida tseriya na ranevuyu reparatsiyu // Byulleten eksperimentalnoy biologii. 2016. Vol. 162, № 9. Р. 382–387.

12. Bezuglov E. N., Achkasov E. E., Usmanova E. M. i dr. Rol trombotsitarnykh faktorov rosta v lechenii khronicheskikh professionalnykh zabolevaniy i travm oporno-dvigatelnogo apparata sportsmenov // Materials of the II All-Russian Congress «Medicine for Sport». Moscow, 2012. P. 20–22.

13. Bezuglov E. N., Achkasov E. E., Usmanova E. M. i dr. The use of platelet-derived growth factors in the treatment of injuries lateral ankle ligaments in football. Sportivnaya meditsina: nauka i praktika // Sports medicine: research and practice). 2013. № 1. Р. 31–35.


Review

For citations:


Achkasov E.E., Solomka A.Ya., Ulyanov A.A., Bezuglov Е.N., Orekhova E.V., Zharikova T.M. CLINICAL AND MORPHOLOGICAL ASPECTS OF THE APPLICATION OF PLATELET GROWTH FACTORS IN PATIENTS WITH PILONIDAL CYST WITH ABSCESS. Grekov's Bulletin of Surgery. 2018;177(2):52-56. (In Russ.) https://doi.org/10.24884/0042-4625-2018-177-2-52-56

Views: 596


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 0042-4625 (Print)
ISSN 2686-7370 (Online)