Primary hyperparathyroidism as a cause of pathological fracture in a 16-year-old teenager
Z. S. Matveeva,
I. V. Karpatsky,
A. V. Gostimskii,
S. S. Peredereev,
S. L. Vorobyev,
D. V. Makharoblishvili https://doi.org/10.24884/0042-4625-2022-181-4-66-70
Abstract
This article presents a rare clinical observation of a bone form of primary hyperparathyroidism in a 16-year-old adolescent complicated by a pathological fracture of the right femur. The features of the given case are: late diagnosis of primary hyperparathyroidism in an adolescent with clinical manifestations; complication of the disease with a pathological fracture, which required two-stage treatment, open repositioning and metal plate osteosynthesis; difficulties in the organization of the examination and treatment of the patient, related to the detection of covid-19 and his stay in an infectious department; the need for tactical decision on the sequence of surgical treatment of the fracture and its cause - primary hyperparathyroidism.
About the Authors
Z. S. Matveeva
Saint Petersburg State Pediatric Medical University
Russian Federation
Competing Interests:
Russian Federation
MD, Ph.D. assistant of the Department of Hospital Surgery, St. Petersburg State Pediatric Medical University
2, Litovskaya str., Saint Petersburg, 194100
Competing Interests:
The authors declare no conflict of interest
I. V. Karpatsky
Saint Petersburg State Pediatric Medical University
Russian Federation
Competing Interests:
Russian Federation
MD, Ph.D. associated professor of the Department of Hospital Surgery, St. Petersburg State Pediatric Medical University
Saint Petersburg
Competing Interests:
The authors declare no conflict of interest
A. V. Gostimskii
Children’s City Multidisciplinary Clinical Specialized Center of High Medical Technologies
Russian Federation
Competing Interests:
Russian Federation
MD, Ph.D. Sc.D. professor, Head of the Children's city clinical Center of high medical technologies
Saint Petersburg
Competing Interests:
The authors declare no conflict of interest
S. S. Peredereev
Saint Petersburg State Pediatric Medical University
Russian Federation
Competing Interests:
Russian Federation
Candidate of Medical Sciences, Head of Surgical Department №3, St. Petersburg State Pediatric Medical University
Saint Petersburg
Competing Interests:
The authors declare no conflict of interest
S. L. Vorobyev
National Center for Clinical Morphological Diagnostics
Russian Federation
Competing Interests:
Russian Federation
Ph.D. Sc.D. professor, Pathologist, Director of National Center for Clinical Morphological Diagnostics
Saint Petersburg
Competing Interests:
The authors declare no conflict of interest
D. V. Makharoblishvili
Saint Petersburg State Pediatric Medical University
Russian Federation
Competing Interests:
Russian Federation
MD, Ph.D. assistant of the Department of Hospital Surgery, St. Petersburg State Pediatric Medical University
Saint Petersburg
Competing Interests:
The authors declare no conflict of interest
References
1. Clarke B. L. Epidemiology of primary hyperparathyroidism // J. Clin. Densitom. 2013;16(1):8–13. Doi: 10.1016/j.jocd.2012.11.009.
2. Lawson M. L., Miller S. F., Ellis G. et al. Primary hyperparathyroidism in a paediatric hospital // QJM. 1996;89:921–932. Doi: 10.1093/qjmed/89.12.921.
3. Allo M., Thompson N. W., Harness J. K., Nishiyama R. H. Primary hyperparathyroidism in children, adolescents, and young adults // World J. Surg. 1982;6:771–776. Doi: 10.1007/BF01655371.
4. Harman C. R., van Heerden J. A., Farley D. R. et al. Sporadic primary hyperparathyroidism in young patients: a separate disease entity? // Arch. Surg. 1999;134:651–655. Doi: 10.1001/archsurg.134.6.651.
5. Roizen J., Levine M. A. Primary hyperparathyroidism in children and adolescents // J. Chin. Med. Assoc. 2012;75(9):425–434. Doi: 10.1016/j.jcma.2012.06.012.
6. Alagaratnam S., Kurzawinski T. R. Aetiology, diagnosis and surgical treatment of primary hyperparathyroidism in children: New Trends // Horm. Res. Paediatr. 2015;83:365–375. Doi: 10.1159/000381622.
7. Davidson J. T., Lam C. G., McGee R. B. et al. Parathyroid Cancer in the Pediatric Patient // J Pediatr. Hematol. Oncol. 2016;38(1):32–37. Doi: 10.1097/MPH.0000000000000443.
8. Pashtan I., Grogan R. H., Kaplan S. P. et al. Primary hyperparathyroidism in adolescents: the same but different // Pediatr. Surg. Int. 2013;29(3):275–279. Doi: 10.1007/s00383-012-3222-3.
9. Dedov I. I., Mokrysheva N. G., Mirnaya S. S. et al. Epidemiology of primary hyperparathyroidism In Russia (the first results from the database of Federal state institution «Endocrinological Research Center» // Problems of endocrinology. 2011;57(3):3–10. (In Russ.).
10. Muller H. Sex, age and hyperparathyroidism // Lancet. 1969;1:449–450.
11. Kollars J., Zarroug A. E., van Heerden J. et al. Primary hyperparathyroidism in pediatric patients // Pediatrics. 2005;115(4):1073.
12. Gostimsky A. V., Matveeva Z. S., Romanchishen A. F. et al. Primary hyperparathyroidism in childhood // Pediatrician. 2017;8(5):20–24. Doi: 10.17816/PED8520-24. (In Russ.).
13. Ramkumar S., Kandasamy D., Vijay M. K. et al. Genu valgum and primary hyperparathyroidism in children // Int. J. Case Rep. Images. 2014;5(6):401–407. Doi: 10.1210/jc.2012-4022.
14. Mamedova E. O., Mokrysheva N. G., Rozhinskaya L. Y. Characteristics of primary hyperparathyroidism in young patients // Problems of Endocrinology. 2018;64(3):163–169. Doi:10.14341/probl9399. (In Russ.).
15. Li C. C., Yang C., Wang S. et al. 10-year retrospective study of primary hyperparathyroidism in children // Exp. Clin. Endocrinol. Diabetes. 2012;120:229–233. Doi: 10.1055/s-0032-1301895.
16. Alagaratnam S., Brain C., Spoudeas H. et al. Surgical treatment of children with hyperparathyroidism: single centre experience // J. Pediatr. Surg. 2014;49(11):1539–43. Doi: 10.1016/j.jpedsurg.2014.05.032.
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For citations:
Matveeva Z.S., Karpatsky I.V., Gostimskii A.V., Peredereev S.S., Vorobyev S.L., Makharoblishvili D.V. Primary hyperparathyroidism as a cause of pathological fracture in a 16-year-old teenager. Grekov's Bulletin of Surgery. 2022;181(4):66-70. (In Russ.) https://doi.org/10.24884/0042-4625-2022-181-4-66-70
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