Risk stratification of anastomotic leakages after colonic resection and reconstructive procedures

The OBJECTIVE to analyze the available researches over the past 5 years and systematized the main groups of factors, which leading to the leakages of colonic anastomoses after resection and reconstructive procedures. Literature analysis was carried in the medical databases PubMed, Medline, Cochrane Library, Web of Science. 22 randomized trials and meta-analyses were included in the literature review. All researches investigated large sample of patients presented and the number of factors evaluated with statistically significant reliability. We analyzed and presented the controlled and uncontrolled factors, which were leading to leakages of colonic anastomoses after reconstructive and resection procedures at different stages of treatment of this category of patients. The frequency of the development of the leakages of interstitial anastomoses according to the studied literature is high. Evaluation of proven factors in the preoperative period will in most cases reduce the risks and, as a consequence, the frequency of leakages of colonic anastomoses. This will be significantly improved to the results of treatment of coloproctological patients. 

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