The role of thymectomy in the treatment of myasthenia
https://doi.org/10.24884/0042-4625-2024-183-5-49-56
Abstract
A systematic review of the data of domestic and foreign literature on the treatment of myasthenia was carried out. Special attention was paid to indications for thymectomy and its effect depending on various prognostic factors. Pubmed, Elibrary, UpToDate databases were used to search for sources. Based on the analysis of literary sources, data on the treatment of myasthenia in tumor and non-tumor pathology of the thymus gland was presented; indications for surgical treatment were clarified. A brief historical review of the use of the surgical method in patients with myasthenia was carried out. The methods of conservative treatment were described. Attention was paid to current trends in surgical approaches for myasthenia as well as repeated operations for refractory course of myasthenia.
Minimally invasive thymectomy is a pathogenetically justified, modern, safe and reproducible treatment option for patients with thymic and non-thymic myasthenia.
About the Authors
D. Ye. Martinova
Р. A. Hertsen Moscow Oncology Research Institute – Branch of the National Medical Research Radiological Centre
Russian Federation
Russian Federation
Martinova Dina Ye., Thoracic Surgeon of the Thoracic Department
Moscow
О. V. Pikin
Р. A. Hertsen Moscow Oncology Research Institute – Branch of the National Medical Research Radiological Centre
Russian Federation
Russian Federation
Pikin Oleg V., Dr. of Sci. (Med.), Professor, Head of the Department of Thoracic Surgery
Moscow
A. B. Ryabov
Р. A. Hertsen Moscow Oncology Research Institute – Branch of the National Medical Research Radiological Centre
Russian Federation
Russian Federation
Ryabov Andrey B., Dr. of Sci. (Med.), Professor, Deputy General Director of National Medical Research Radiological Centre for Surgery, Head of the Department of Thoracoabdominal Oncosurgery
Moscow
N. I. Sherbakova
Р. A. Hertsen Moscow Oncology Research Institute – Branch of the National Medical Research Radiological Centre
Russian Federation
Russian Federation
Sherbakova Natalya I., Dr. of Sci. (Med.), Professor, Neurologist
Moscow
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Martinova D.Ye., Pikin О.V., Ryabov A.B., Sherbakova N.I. The role of thymectomy in the treatment of myasthenia. Grekov's Bulletin of Surgery. 2024;183(5):49-56. (In Russ.) https://doi.org/10.24884/0042-4625-2024-183-5-49-56
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