Surgical tactics for esophageal cancer with complete pathomorphosis after chemoradiotherapy
B. V. Sigua,
A. A. Kurkov,
A. V. Belyaeva,
Zh. V. Bryantseva,
A. I. Arseniev,
E. L. Latariya,
O. B. Tcelykovskaia,
I. P. Mavidi,
K. V. Arutyunyan,
S. A. Vinnichuk,
V. P. Zemlyanoy https://doi.org/10.24884/0042-4625-2024-183-1-42-46
Abstract
Esophageal cancer is an oncological disease with a poor prognosis due to late diagnosis and detection of the tumor at a late stage. At present, the combined method of treatment is generally accepted for this pathology, starting from stage IIA. Preoperative chemoradiation therapy in this approach helps to achieve not only partial but also complete regression of the tumor. The question of the necessity of surgical tactics in this group of patients, due to the lack of clear recommendations, remains controversial at present. The article presents a successful case of neoadjuvant chemoradiation therapy, which made it possible to achieve not only clinical, but also complete pathomorphological regression of the tumor. This tumor response to chemoradiation therapy occurs in less than a third of all patients with esophageal cancer. Despite this, complete regression of the tumor does not mean recovery.
About the Authors
B. V. Sigua
North-Western State Medical University named after I.I. Mechnikov
Russian Federation
Competing Interests:
Russian Federation
Sigua Badri V., Dr. of Sci. (Med.), Professor of the Department of Faculty Surgery named after I. I. Grekov
41, Kirochnaya str., Saint Petersburg, 191015
Competing Interests:
The authors declare no conflict of interest
A. A. Kurkov
North-Western State Medical University named after I.I. Mechnikov
Russian Federation
Competing Interests:
Russian Federation
Kurkov Alexey A., Cand. of Sci. (Med.), Assistant of the Department of Faculty Surgery with the Course of Endoscopy named after I. I. Grekov
41, Kirochnaya str., Saint Petersburg, 191015
Competing Interests:
The authors declare no conflict of interest
A. V. Belyaeva
North-Western State Medical University named after I.I. Mechnikov
Russian Federation
Competing Interests:
Russian Federation
Belyaeva Anna V., Cand. of Sci. (Med.), Oncologist, Head of the Oncology Department of antitumor drug Therapy
41, Kirochnaya str., Saint Petersburg, 191015
Competing Interests:
The authors declare no conflict of interest
Zh. V. Bryantseva
North-Western State Medical University named after I.I. Mechnikov
Russian Federation
Competing Interests:
Russian Federation
Bryantseva Zhanna V., Cand. of Sci. (Med.)
41, Kirochnaya str., Saint Petersburg, 191015
Competing Interests:
The authors declare no conflict of interest
A. I. Arseniev
North-Western State Medical University named after I.I. Mechnikov
Russian Federation
Competing Interests:
Russian Federation
Arseniev Andrey I., Dr. of Sci. (Med.), Professor
41, Kirochnaya str., Saint Petersburg, 191015
Competing Interests:
The authors declare no conflict of interest
E. L. Latariya
North-Western State Medical University named after I.I. Mechnikov
Russian Federation
Competing Interests:
Russian Federation
Latariya Elgudzha L., Cand. of Sci. (Med.), Associate Professor, The Vice-Rector for Clinical Work is the Chief Physician of the clinics
41, Kirochnaya str., Saint Petersburg, 191015
Competing Interests:
The authors declare no conflict of interest
O. B. Tcelykovskaia
North-Western State Medical University named after I.I. Mechnikov
Russian Federation
Competing Interests:
Russian Federation
Tcelykovskaia Olesia B., Clinical Resident of the Department of Faculty Surgery with the Course of Endoscopy named after I. I. Grekov
41, Kirochnaya str., Saint Petersburg, 191015
Competing Interests:
The authors declare no conflict of interest
I. P. Mavidi
Pavlov University
Russian Federation
Competing Interests:
Russian Federation
Mavidi Inna P., Associate Professor of the Department of Surgical Diseases of the Faculty of Stomatology named after A.M. Ganichkin
Saint Petersburg
Competing Interests:
The authors declare no conflict of interest
K. V. Arutyunyan
North-Western State Medical University named after I.I. Mechnikov
Russian Federation
Competing Interests:
Russian Federation
Arutyunyan Kseniya V.
41, Kirochnaya str., Saint Petersburg, 191015
Competing Interests:
The authors declare no conflict of interest
S. A. Vinnichuk
North-Western State Medical University named after I.I. Mechnikov
Russian Federation
Competing Interests:
Russian Federation
Vinnichuk Sergei A., Cand. of Sci. (Med.), Associate Professor
41, Kirochnaya str., Saint Petersburg, 191015
Competing Interests:
The authors declare no conflict of interest
V. P. Zemlyanoy
North-Western State Medical University named after I.I. Mechnikov
Russian Federation
Competing Interests:
Russian Federation
Zemlyanoy Vyacheslav P., Dr. of Sci. (Med.), Professor, Head of the Department of Faculty Surgery named after I. I. Grekov
41, Kirochnaya str., Saint Petersburg, 191015
Competing Interests:
The authors declare no conflict of interest
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Sigua B.V., Kurkov A.A., Belyaeva A.V., Bryantseva Zh.V., Arseniev A.I., Latariya E.L., Tcelykovskaia O.B., Mavidi I.P., Arutyunyan K.V., Vinnichuk S.A., Zemlyanoy V.P. Surgical tactics for esophageal cancer with complete pathomorphosis after chemoradiotherapy. Grekov's Bulletin of Surgery. 2024;183(1):42-46. (In Russ.) https://doi.org/10.24884/0042-4625-2024-183-1-42-46
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