Cryosurgery for radical gastropancreatoduodenal resections in patients with stage IB–IIA pancreatic head cancer

Abstract

In order to improve the long–term results of treatment of ductal cancer of the pancreatic head in stage IB–IIA, cryotherapy was performed during gastropancreatoduodenal resections involving the entire pancreatic head tissue in the cold zone. At the same time, freezing was performed twice: 1) before mobilizing the head of the pancreas; 2) after removing the drug on the bed of its removed part. Intraoperative cryotherapy was used in 27 patients with stage IB–IIA ductal cancer. The control group consisted of 31 patients who underwent standard operations without cryoablation. The results of the examination of patients within 7 years of the postoperative period showed the effectiveness of intraoperative cryotherapy on the tumor. Thus, among 10 patients operated on with stage IB of the disease using cryotherapy, tumor recurrence was detected in one patient after five years. While among 12 patients with the same stage, but without cryotherapy, a relapse occurred in 5 patients. The same trend was found in patients operated on during stage IIA of the disease.