Pulmonary embolism in multifield hospital: results of autopsy study
https://doi.org/10.24884/0042-4625-2017-176-4-60-66
Abstract
OBJECTIVE. Modern data analysis of the rate of pulmonary embolism (PE) development was made. A comparative analysis of epidemiology dynamics of diseases was carried out and included of the past 40 years. MATERIAL AND METHODS. The retrospective analysis of 2042 autopsies was conducted in autopsy department of Municipal clinical hospital №1 named after N. I. Pirogov at the period from 2011 to 2013. According to results of necropsies, 440 samples of pulmonary embolism of different localization and their terms were found. RESULTS. Conducted study demonstrated a relative growth of the development rate of pulmonary embolism and fatal pulmonary embolism. Pulmonary embolism had been revealed by autopsy in 4,4 % patients in 1964-1973, but the rate of PE increased to 21,5 % in 2011-2013. The fatal PE was noted in 9,3 % of autopsies in 2011-2013, though it counted 2,5 % in 1964- 1973. CONCLUSIONS. The rate of pulmonary embolism development increased in 5 times. The growth of the PE rate was revealed in postoperative period and significant part of complications (18,5 %) were associated with fatal PE.
About the Authors
A. I. Kirienko
N. I. Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
I. S. Lebedev
Municipal clinical hospital № 1 named after N. I. Pirogov
Russian Federation
Russian Federation
N. I. Polyanko
Department of public health
Russian Federation
Russian Federation
O. O. Orekhov
Department of public health
Russian Federation
Russian Federation
A. P. Raksha
Municipal clinical hospital № 1 named after N. I. Pirogov
Russian Federation
Russian Federation
O. O. Turishcheva
N. I. Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
E. S. Ivanchikova
Municipal clinical hospital № 1 named after N. I. Pirogov
Russian Federation
Russian Federation
M. A. Chumakova
N. I. Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
S. G. Gavrilov
N. I. Pirogov Russian National Research Medical University
Russian Federation
Russian Federation
References
1. Кириенко А. И., Панченко Е. П., Андрияшкин А. В. Венозный тромбоз в практике терапевта и хирурга. М. : Планида, 2012. 336 с.
2. Савельев В. С., Кириенко А. И., Андрияшкин В. В., Золотухин И. А., Леонтьев С. Г., Андрияшкин А. В. Итоги проекта «Территория безопасности от венозных тромбоэмболических осложнений» // Флебология. 2011. № 4. С. 4-9.
3. Савельев В. С., Яблоков Е. Г., Кириенко А. И. Массивная тромбоэмболия лёгочной артерии. М. : Медицина, 1990. 336 с.
4. Савельев В. С., Яблоков Е. Г., Кириенко А. И. Тромбоэмболия лёгочных артерий. М. : Медицина, 1979. 264 с.
5. Флебология : Руководство для врачей / Под ред. В. С. Савельева. М. : Медицина, 2001. 664 c.
6. Шабунин А. В., Гаврилов С. Г., Пустовойт А. А., Бычкова Т. В., Каралкин А. В., Золотухин И. А. Сравнение эффективности хирургической и консервативной тактики при остром восходящем варикотромбофлебите большой подкожной вены бедра // Флебология. 2013. № 2. С. 10-14.
7. Carson J. L., Kelley M. A., Duff A. et al. The clinical course of pulmonary embolism // N. Engl. J. Med. 1992. Vol. 326. P. 1240- 1245.
8. Collins R., Scrimgeour A., Yusuf S. Reduction in fatal pulmonary embolism and venous thrombosis by perioperative administration of subcutaneous heparin: overview of results of randomized trials in general, orthopedic, and urologic surgery // N. Engl. J. Med. 1988. Vol. 318. P. 1162-1173.
9. Geerts W. H., Bergqvist D., Pineo G. F., Heit J. A., Samama C. M., Lassen M. R., Colwell C. W. Prevention of venous throm boembolism : American College of Chest Physicians Evi-dence-Based Clinical Practice Guidelines (8th Ed.) // Chest. 2008. Vol. 133 (Suppl. 6). P. 381-453.
10. Goldhaber S. Z., Visani L., De Rosa M. Acute pulmonary embolism: clinical outcomes in the International Cooperative Pulmonary Embolism Registry (ICOPER) // Lancet. 1999. Vol. 353. P. 1386- 1389.
11. Mismetti P., Laporte S., Darmon J. Y., Buchmüller A., Decousus H. Meta-analysis of low molecular weight heparin in the prevention of venous thromboembolism in general surgery // Brit. J. Surg. 2001. Vol. 88. P. 913-930.
12. Obi A. T., Pannucci C. J., Nackashi A., Abdullah N., Alvarez R., Bahl V., Wakefield T. W., Henke P. K. Validation of the Caprini venous thromboembolism risk assessment model in critically ill surgical patients // JAMA Surg. 2015. Vol. 150. P. 941-948.
13. Oger E. Incidence of venous thromboembolism : a community-based study in Western France. EPI-GETBP Study Group. Groupe d’Etude de la Thrombose de Bretagne Occidentale // Thromb. Haemost. 2000. Vol. 83. P. 657-660.
14. Ro A., Kageyama N., Tanifuji T., Fukunaga T. Pulmonary thromboembolism : overview аnd update from medicolegal aspects // Leg. Med. (Tokyo). 2008. № 10. P. 57-71.
15. Stein P. D., Beemath A., Olson R. E. Trends in the incidence of pulmonary embolism and deep venous thrombosis in hospitalized patients // Amer. J. Cardiol. 2005. Vol. 95. P. 1525-1526.
16. Wells P.S., Forgie M. A., Rodger M. A. Treatment of venous thromboembolism // JAMA. 2014. Vol. 311. P. 717-728.
17. Wickham N., Gallus A. S., Walters B. N., Wilson A. Prevention of venous thromboembolism in patients admitted to Australian hospitals : summary of National Health and Medical Research Council clinical practice guideline // Intern. Med. J. 2012. Vol. 42. P. 698-708.
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For citations:
Kirienko A.I., Lebedev I.S., Polyanko N.I., Orekhov O.O., Raksha A.P., Turishcheva O.O., Ivanchikova E.S., Chumakova M.A., Gavrilov S.G. Pulmonary embolism in multifield hospital: results of autopsy study. Grekov's Bulletin of Surgery. 2017;176(4):60-66. (In Russ.) https://doi.org/10.24884/0042-4625-2017-176-4-60-66
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