Actual methods of treatment of parar ectal fistulas in Crohn’s disease
https://doi.org/10.24884/0042-4625-2025-184-4-102-109
Abstract
The treatment of perianal Crohn’s disease remains a significant challenge due to the complexity of its pathogenesis and the lack of standardized treatment guidelines. The high rate of surgical failure, frequent exacerbations and recurrences, as well as the risks of anal incontinence and rectal strictures, highlight the need for more effective therapeutic strategies. This review examines various treatment approaches for pararectal fistulas in perianal Crohn’s disease. However, conflicting findings in the literature, the limited number of clinical studies, and the absence of standardized criteria for evaluating treatment outcomes make it difficult to draw definitive conclusions about the efficacy of existing therapeutic modalities. Further well-designed studies with a stronger evidence base are essential to establish optimal treatment strategies.
About the Authors
A. A. Kamanin
Pavlov University
Russian Federation
Competing Interests:
Russian Federation
Kamanin Alexey A., Cand. of Sci. (Med.), Associate Professor of the Department of General Surgery with Clinic
6-8, L’va Tolstogo str., Saint Petersburg, 197022
Competing Interests:
The authors declare no conflict of interest.
D. G. Nomokonov
Pavlov University
Russian Federation
Competing Interests:
Russian Federation
Nomokonov Dmitry G., Senior Assistant of the Department of General Surgery with Clinic
6-8, L’va Tolstogo str., Saint Petersburg, 197022
Competing Interests:
The authors declare no conflict of interest.
R. V. Cheminava
Pavlov University
Russian Federation
Competing Interests:
Russian Federation
Cheminava Revaz V., Dr. of Sci. (Med.), Professor of the Department of General Surgery with Clinic
6-8, L’va Tolstogo str., Saint Petersburg, 197022
Competing Interests:
The authors declare no conflict of interest.
V. P. Morozov
Pavlov University
Russian Federation
Competing Interests:
Russian Federation
Morozov Victor P., Dr. of Sci. (Med.), Professor, Head of the Department of General Surgery with Clinic
6-8, L’va Tolstogo str., Saint Petersburg, 197022
Competing Interests:
The authors declare no conflict of interest.
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Kamanin A.A., Nomokonov D.G., Cheminava R.V., Morozov V.P. Actual methods of treatment of parar ectal fistulas in Crohn’s disease. Grekov's Bulletin of Surgery. 2025;184(4):102-109. (In Russ.) https://doi.org/10.24884/0042-4625-2025-184-4-102-109
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