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Features of surgical treatment of a patient with ACTH-ectopic syndrome of pulmonary localization in combination with HIV infection

https://doi.org/10.24884/0042-4625-2025-184-5-79-84

Abstract

This clinical case demonstrates the feasibility of successful surgical treatment for a patient with severe ACTH-ectopic syndrome complicated by HIV infection. Understanding the specific characteristics of HIV infection in cancer patients allowed us to effectively perform surgery, predict the severity of the postoperative period and, consequently, implement appropriate preventive measures for successful cure of the patient.

About the Authors

M. Yu. Pikunov
National Medical Research Center of Surgery named after A. V. Vishnevsky
Russian Federation

Pikunov Michael Yu., Cand. of Sci. (Med.), Senior Research Fellow of the Department of Thoracic Surgery

Moscow



A. A. Pechetov
National Medical Research Center of Surgery named after A. V. Vishnevsky
Russian Federation

Pechetov Alexey A., Cand. of Sci. (Med.), Head of the Department of Thoracic Surgery

Moscow



I. I. Danilov
National Medical Research Center of Surgery named after A. V. Vishnevsky
Russian Federation

Danilov Ilya I., Surgeon of the Department of Thoracic Surgery

Moscow



D. A. Kabanova
National Medical Research Center of Surgery named after A. V. Vishnevsky
Russian Federation

Kabanova Daria A., Clinical Resident

Moscow



References

1. Pikunov M. Yu., Pechetov A. A., Golounina O. O. et al. Surgical Treatment of Patients with Acth-Producing Neuroendocrine Tumor of Bronchopulmonary Localization: the Experience of National Medical Research Center for Surgery Named after A. V. Vishnevsky. Novosti Khirurgii. 2023;31(5):362–373. (In Russ.). https://doi.org/10.18484/23050047.2023.4.265.

2. Pegina P. A., Likhobabina A. S. Neuroendocrine tumor of the lungs: a clinical case. Youth Innovation Bulletin. 2024;13(Supplement 1):268–272. (In Russ.).

3. Serban A. L., Rosso L., Mendogni P. et al. Case Report: A Challenging Localization of a Pulmonary Ectopic ACTH-Secreting Tumor in a Patient With Severe Cushing’s Syndrome. Front Endocrinol (Lausanne). 2021;12:687539. https://doi.org/10.3389/fendo.2021.687539.

4. Doi M., Sugiyama T., Izumiyama H. et al. Clinical features and management of ectopic ACTH syndrome at a single institute in Japan. Endocr J. 2010;57(12):1061–9. https://doi.org/10.1507/endocrj.k10e-265.

5. Kaprin A. D., Voronin E. E., Rassokhin V. V. et al. Malignant neoplasms associated with HIV infection. Problems and solutions (problem outline) Journal of Modern Oncology. 2021;23(3):502–507. (In Russ.). https:// doi.org/10.26442/18151434.2021.3.201041.

6. Sinitsyn M. V., Reshetnikov M. N., Barskiy B. G. et al. diagnostic surgery in HIV-infected patients with damage of chest organs. HIV Infection and Immunosuppressive Disorders. 2018;10(2):96–102. (In Russ.) https:// doi.org/10.22328/2077-9828-2018-10-2-96-102.

7. Federal Law of March 30, 1995 No. 38-FZ “On the Prevention of the Spread in the Russian Federation of the Disease Caused by the Human Immunodeficiency Virus (HIV Infection)”. URL: https://base.garant. ru/10104189/ (accessed: 17.10.25). (In Russ.).

8. Order of the Ministry of Health of the Russian Federation of December 20, 2012 No. 1177n “On approval of the procedure for transmitting informed voluntary consent to medical intervention and refusal of medical intervention in relation to certain types of medical interventions, forms of informed voluntary consent to types of medical interventions and refusals of types of medical interventions.” URL: https://normativ.kontur. ru/document?moduleId=1&documentId=259384 (accessed: 17.10.25).


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For citations:


Pikunov M.Yu., Pechetov A.A., Danilov I.I., Kabanova D.A. Features of surgical treatment of a patient with ACTH-ectopic syndrome of pulmonary localization in combination with HIV infection. Grekov's Bulletin of Surgery. 2025;184(5):79-84. (In Russ.) https://doi.org/10.24884/0042-4625-2025-184-5-79-84

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ISSN 0042-4625 (Print)
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