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Preoperative preparation and surgical treatment of a patient with a complicated form of refractory Crohn’s disease

https://doi.org/10.24884/0042-4625-2026-185-2-92-95

Abstract

The treatment of patients with Crohn’s disease with total colon inflammation and persistent refractoriness to pathogenetic therapy poses a significant challenge for surgeons and resuscitation specialists. The issues of preoperative preparation, timing of surgical intervention, and surgical tactics are highly relevant. The described clinical case demonstrates the importance of an interdisciplinary approach and provides an example of effective preoperative preparation, as well as successful colectomy in a patient with Crohn’s disease, total inflammatory-necrotic colitis that was resistant to pathogenetic therapy and was accompanied by severe intoxication with systemic inflammatory response syndrome.

About the Authors

A. A. Kamanin
Pavlov University
Russian Federation

Kamanin Aleksei A., Cand. of Sci. (Med.), Associate Professor of the Department of General Surgery with Clinic, Surgeon of the Surgical Department № 3 of the Research Institute of Surgery and Emergency Medicine

6-8, L’va Tolstogo str., Saint Petersburg, 197022


Competing Interests:

The authors declare no conflict of interest.



V. P. Morozov
Pavlov University
Russian Federation

Morozov Viktor P., Dr. of Sci. (Med.), Professor, 
Head of the Department of General Surgery with Clinic

6-8, L’va Tolstogo str., Saint Petersburg, 197022


Competing Interests:

The authors declare no conflict of interest.



P. I. Bogdanov
Pavlov University
Russian Federation

Bogdanov Piotr. I., Cand. of Sci. (Med.), Associate Professor of the Department of General Surgery with Clinic, Head of the Surgical Department № 3 of the Research Institute of Surgery and Emergency Medicine

6-8, L’va Tolstogo str., Saint Petersburg, 197022


Competing Interests:

The authors declare no conflict of interest.



A. Yu. Korolkov
Pavlov University
Russian Federation

Korolkov Andrei. Yu., Dr. of Sci. (Med.), Professor, Head of the Department of General and Emergency Surgery of the Research Institute of Surgery and Emergency Medicine, Head of the Department of Hospital Surgery № 2, Deputy Chief Physician of the Clinic for Surgery

6-8, L’va Tolstogo str., Saint Petersburg, 197022


Competing Interests:

The authors declare no conflict of interest.



D. G. Nomokonov
Pavlov University
Russian Federation

Nomokonov Dmitriy G., Senior Laboratory Assistant of the Department of General Surgery with Clinic, Surgeon of the Surgical Department № 3 of the Research Institute of Surgery and Emergency Medicine

6-8, L’va Tolstogo str., Saint Petersburg, 197022


Competing Interests:

The authors declare no conflict of interest.



O. B. Shchukina
Pavlov University
Russian Federation

Shchukina Oksana B., Dr. of Sci. (Med.), Professor of Department of General Medical Practice (Family Medicine), Head of the Inflammatory Bowel Diseases (IBD) Department, Outpatient Clinic with a Clinical and Diagnostic Center

6-8, L’va Tolstogo str., Saint Petersburg, 197022


Competing Interests:

The authors declare no conflict of interest.



References

1. Sandborn WJ, Feagan BG, Hanauer SB, Lochs H, Löfberg R, Modigliani R, et al. A review of activity indices and efficacy endpoints for clinical trials of medical therapy in adults with Crohn"s disease. Gastroenterology 2002;122:512–30. doi: 10.1053/gast.2002.31072

2. Donnellan, C.F. Nutritional management of Crohn's disease / C.F. Donnellan, L.H. Yann, S. Lal // Therap. Adv. Gastroenterol. – 2013. – Vol. 6. – P. 231-242. doi: 10.1177/1756283X13477715

3. Gionchetti P, Dignass A, Danese S. et al. 3rd European Evidence-based Consensus on the Diagnosis and Management of Crohn's Disease 2016: Part 2: Surgical Management and Special Situations. J Crohns Colitis. 2017 Feb;11(2):135-149. doi: 10.1093/ecco-jcc/jjac104

4. Pershko A.M., Grinevich V.B., Solovyov I.A., Kurilo D.P. Modern strategies of therapeutic and surgical treatment of Crohn’s disease. Experimental and Clinical Gastroenterology. 2020;174(4):89-95. (In Russ.). doi: 10.37489/0235-2990-2024-69-1-2-59-64

5. Bernell, O. Risk factors for surgery and postoperative recurrence in Crohn’s disease / O. Bernell, A. Lapidus, G. Hellers // Ann. Surg. – 2000. – Vol. 231. – P. 38-45. doi: 10.1097/00000658-200001000-00006

6. Belikovа M.Ya., Gorshenin T.L., Borovik I.K., Sizov Yu.A. Crohn’s disease penetrating form. Difficulties of diagnostics and preoperative planning (clinical case). Koloproktologia. 2023;22(3):121-127. doi: 10.1097/00000658-200001000-00006

7. Ford MM. Crohn`s Disease Obstructions. Clin Colon Rectal Surg. 2021 Jul: 34 (4): 227-232. doi: 10.1055/s-0041-1729926

8. Lopez NE, Zaghyian K, Fleshner P. Is There a Role for Ileal Pouch Anal Anastomosis in Crohn's Disease? Clin Colon Rectal Surg. 2019 Jul;32(4):280-290. doi: 10.1055/s-0039-1683917


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For citations:


Kamanin A.A., Morozov V.P., Bogdanov P.I., Korolkov A.Yu., Nomokonov D.G., Shchukina O.B. Preoperative preparation and surgical treatment of a patient with a complicated form of refractory Crohn’s disease. Grekov's Bulletin of Surgery. 2026;185(2):92-95. (In Russ.) https://doi.org/10.24884/0042-4625-2026-185-2-92-95

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