Concentrated suspension of platelets and collagen in the treatment of venous trophic ulcers of large size
https://doi.org/10.24884/0042-4625-2019-178-1-59-62
Abstract
The objective was to evaluate the efficacy of donor thromboconcentrate and collagen preparations for improving the results of autodermoplasty of extensive venous trophic ulcers.
Material and methods. The study included 66 patients with extensive venous trophic ulcers larger than 20 cm2 in the second 2 phase of wound process. Patients were randomly divided into the main group and 3 control groups.
Results. The activation of regeneration processes using a combination of platelet-rich donor plasma and native unreconstructed collagen before autodermoplasty leads to improving the viability and engraftment of transplant, progressive decreasing the area of the wound defect.
Conclusion. The use of a combination of donor thromboconcentrate and collagen preparations statistically significantly improves the results of skin transplantation.
Supporting agencies: Grant from the President of the Russian Federation № MK-3494.2017.7
About the Authors
M. A. Aralova
Voronezh State Medical University named after N. N. Burdenko
Russian Federation
Russian Federation
Corresponding author: Мaria V. Aralova, Voronezh State Medical University of N. N. Burdenko, 10 Studencheskaya street, Voronezh, Russia, 394036. E-mail: mashaaralova@mail.ru.
A. A. Glukhov
Voronezh State Medical University named after N. N. Burdenko
Russian Federation
Russian Federation
Alexander A. Glukhov
Voronezh
References
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Review
For citations:
Aralova M.A., Glukhov A.A. Concentrated suspension of platelets and collagen in the treatment of venous trophic ulcers of large size. Grekov's Bulletin of Surgery. 2019;178(1):59-62. (In Russ.) https://doi.org/10.24884/0042-4625-2019-178-1-59-62
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