Preview

Grekov's Bulletin of Surgery

Advanced search

Gastrointestinal bleeding in deep infiltrative endometriosis

https://doi.org/10.24884/0042-4625-2026-185-1-65-73

Abstract

The article demonstrates approaches to the diagnosis and treatment of intestinal endometriosis with a complication in the form of intestinal bleeding. In the first case, intestinal bleeding in a young woman was caused by endometriosis through germination of the sigmoid colon wall, which is a classic example of a combined lesion of endometriosis of the pelvic organs. The second case describes a rare variant of intestinal bleeding caused by endometriosis of the duodenum in a woman during the menopausal transition.

About the Authors

S. L. Nepomnyashchaya
St. Petersburg State University
Russian Federation

Nepomnyashchaya Svetlana L., Cand. of Sci. (Med.), Associate Professor, Head of the Scientific and Educational Department, Surgeon, Oncologist

7/9, Universitetskaya embankment, Saint Petersburg, 199034

ResearcherID: E-5875-2017


Competing Interests:

The authors declare no conflict of interest.



A. M. Belousov
St. Petersburg State University
Russian Federation

Belousov Aleksandr M., Dr. of Sci. (Med.), Deputy Director for Medical Affairs (Surgery and Oncology), Surgeon, Oncologist, N. I. Pirogov Clinic of High Medical Technologies

7/9, Universitetskaya embankment, Saint Petersburg, 199034


Competing Interests:

The authors declare no conflict of interest.



K. G. Shostka
St. Petersburg State University
Russian Federation

Shostka Kirill G., Cand. of Sci. (Med.), Head of the Oncological Department № 2, Oncologist, N. I. Pirogov Clinic of High Medical Technologies

7/9, Universitetskaya embankment, Saint Petersburg, 199034


Competing Interests:

The authors declare no conflict of interest.



V. A. Malkov
St. Petersburg State University
Russian Federation

Malkov Vladimir A., Head of the Endoscopic Department, Endoscopist, N. I. Pirogov Clinic of High Medical Technologies,

7/9, Universitetskaya embankment, Saint Petersburg, 199034


Competing Interests:

The authors declare no conflict of interest.



S. I. Senchilo
St. Petersburg State University
Russian Federation

Senchilo Stanislav I., Endoscopist of the Endoscopic Department, N. I. Pirogov Clinic of High Medical Technologies

7/9, Universitetskaya embankment, Saint Petersburg, 199034


Competing Interests:

The authors declare no conflict of interest.



A. S. Basos
St. Petersburg State University
Russian Federation

Basos Aleksandr S., Cand. of Sci. (Med.), Head of the Department of Operative Gynecology, Obstetrician-Gynecologist of the 1st Category, Gynecological Department, N. I. Pirogov Clinic of High Medical Technologies

7/9, Universitetskaya embankment, Saint Petersburg, 199034

AuthorID: 1308476


Competing Interests:

The authors declare no conflict of interest.



T. V. Saveljeva
St. Petersburg State University
Russian Federation

Saveljeva Tatjana V., Cand. of Sci. (Med.), Radiologist of the Highest Category, Department of Diagnostic Radiology, N. I. Pirogov Clinic of High Medical Technologies

7/9, Universitetskaya embankment, Saint Petersburg, 199034

AuthorID: 1075438


Competing Interests:

The authors declare no conflict of interest.



N. S. Kharlov
St. Petersburg State University
Russian Federation

Kharlov Nikita S., Head of the Gynecological Department, Oncologist, N. I. Pirogov Clinic of High Medical Technologies

7/9, Universitetskaya embankment, Saint Petersburg, 199034

AuthorID: 825631


Competing Interests:

The authors declare no conflict of interest.



V. Yu. Dubrovin
St. Petersburg State University
Russian Federation

Dubrovin Vladislav Yu., Resident Physician of the Oncological Department № 2, N. I. Pirogov Clinic of High Medical Technologies

7/9, Universitetskaya embankment, Saint Petersburg, 199034


Competing Interests:

The authors declare no conflict of interest.



References

1. Patazzini F., Esposito G., Tozzi L. et al. Epidemiology of endometriosis and its comorbidities. Eur.J.Obstet Gynecol. Reproid Biol. 2017. Vol. 209. P. 3–7. https://doi.org/10.1016/j.ejogrb.2016.04.021. PMID: 27216973.

2. Jaramillo-Cardoso A., Shenoy-Bhangle A. S., VanBuren W. M. et al. Imaging of gastrointestinal endometriosis: what the radiologist should know. Abdominal Radiology. 2020. Vol. 45, № 6. P. 1694–1710. https:// doi.org/10.1007/s00261-020-02459-w.

3. Bong J. W., Yu C. S., Lee J. L., Kim C. W. et al. Intestinal endometriosis: Diagnostic ambiguities and surgical outcomes. World J Clin Cases. 2019. Vol. 7, № 4. P. 441–451. https://doi.org/10.12998/wjcc.v7.i4.441. PMID: 30842955; PMCID: PMC6397811.

4. Piachas A., Smyrnis P., Tooulias A. Rectosigmoid endometriosis: Diagnostic pitfalls and management – A case report. Clinical Case Reports. 2022. Vol. 10, № 2. P. e05222. https://doi.org/10.1002/ccr3.5222.

5. Pfuetzenreiter V., Loureiro J. F. M., Teixeira C. V., Rossini L. G. B. Correlation of Endoscopic Findings with Suspected Intestinal Endometriosis in the Distal Sigmoid and Rectum as Observed on Transrectal Ultrasonography. Journal of Coloproctology. 2023. Vol. 43, № 01. P. 036–042. https://doi.org/10.1055/s-0043-1764194.

6. Charatsi D., Koukoura O., Ntavela I. G. et al. Gastrointestinal and Urinary Tract Endometriosis: A Review on the Commonest Locations of Extrapelvic Endometriosis. Advances in Medicine. 2018. Vol. 2018. P. 1–11. https://doi.org/10.1155/2018/3461209.

7. Vercellini P., Buggio L., Borghi A. et al. Medical treatment in the management of deep endometriosis infiltrating the proximal rectum and sigmoid colon: a comprehensive literature review. Acta Obstetricia et Gynecologica Scandinavica. 2018. Vol. 97, № 8. P. 942–955. https:// doi.org/10.1111/aogs.13328.

8. Vercellini P., Sergenti G., Buggio L. et al. Advances in the medical management of bowel endometriosis. Best Practice & Research Clinical Obstetrics & Gynaecology. 2021. Vol. 71. P. 78–99. https://doi. org/10.1016/j.bpobgyn.2020.06.004.

9. Hu J., Hosseini M., Hasteh F. et al. Rectal endometriosis mimicking primary rectal adenocarcinoma – Text : electronic. Diagnostic Cytopathology. 2021. Vol. 49, № 12. https://doi.org/10.1002/dc.24847. URL: https://onlinelibrary. wiley.com/doi/10.1002/dc.24847 (date accessed: 19.05.2024).

10. Bonavina G., Taylor H. S. Endometriosis-associated infertility: From pathophisiology to tailored treatment. Front Endocrinol (Lausanne). 2022. Vol. 13. P. 1020827. https://doi.org/10.3389/fendo.2022.1020827. PMID: 36387918; PMCID^ PMC9643365.

11. Pechenikova V. A., Kostyuchek D. F. Extragenital endometriosis: clinicopathologic and immunohistochemical analysis of 45 observations with diverse organ localization. Journal of obstetrics and women’s diseases. 2010. Vol. 59, № 2. P. 69–77. EDN NEBJVL. (In Russ.).

12. Mel’nikov M. V., Chuprynin V. D., Askol’skaya S. V. Issues in the clinical diagnosis of bowel endometriosis. Akush Ginekol (Mosk). 2013. № 5. P. 48–53. (In Russ.).

13. Jayant M., Kaushik R., Punia R. S. Endometriotic stricture of the sigmoid colon presenting with intestinal obstruction. S Afr J Surg. 2014. Vol. 52, № 1. P. 26–28.

14. Alatise O. I., Sabageh D., Ogunniyi S. O., Olaofe O. O. Ileal endometriosis presenting as acute small intestinal obstruction: a case report. West Afr J Med. 2010. Vol. 29, № 5. P. 352–355.

15. Schnieber D., Wagner-Kolb D. Malignant transformation of extragenital endometriosis. Geburtshilfe Frauenheilkd. 1986. Vol. 46, № 9. P. 658–659. https://doi.org/10.1055/ s-2008-1036277.

16. Machairiotis N., Stylianaki A., Dryllis G. et al. Extrapelvic endometriosis: a rare entity or an under diagnosed condition? Diagn Pathol. 2013. Vol. 8. P. 194. https://doi.org/ 10.1186/1746-1596-8-194.

17. Subbaraj L., Bowman C. J., Singh A. A Masked Diagnosis: Sigmoid Endometriosis. ACG Case Reports Journal. 2021. Vol. 8, № 6. P. e00557. https://doi.org/10.14309/crj.0000000000000557.

18. Zemlyanoy V. P., Sigua B. V., Syomin D. S. et al. Diagnosis and surgical treatment of acute intestinal obstruction caused by extragenital form of endometriosis. Herald of North-Western State Medical University named after I. I. Mechnikov. 2020. Vol. 12, № 1. P. 97–101. (In Russ.). https:// doi.org/10.17816/mechnikov17922.

19. Singh S. S., Gude K., Perdeaux E. et al. Surgical Outcomes in Patients With Endometriosis: A Systematic Review. Journal of Obstetrics and Gynaecology Canada. 2020. Vol. 42, № 7. P. 881–888.e11. https://doi.org/10.1016/j.jogc.2019.08.004.

20. Siegenthaler F., Knabben L., Mohr S. et al. Visualization of endometriosis with laparoscopy and near-infrared optics with indocyanine green. Acta Obstet Gynecol Scand. 2020. Vol. 99, № 5. P. 591–597. https://doi.org/10.1111/aogs.13803. PMID: 31943126.

21. Adamyan L. V., Andreeva E. N., Apolikhina I. A. et al. Endometrioz: diagnostika, lechenie i reabilitatsiya. Federal’nye klinicheskie rekomendatsii po vedeniyu bol’nykh. Moscow; 2013. (In Russ.).

22. Danzanova T. Yu., Sinyukova G. T., Zubareva E. A. et al. Difficulties in Differentiation of Malignant Neoplasms and Deep Infiltrative Endometriosis. Journal of oncology: diagnostic radiology and radiotherapy. 2022;5(4):107–116. (In Russ.). https://doi.org/10.37174/2587-7593-2022-5-4-107-116.

23. Yarmolinskaya M. I., Rusina E. I., Semenova V. O., Beganova A. K. Extragenital endometriosis: diagnostic difficulties, modern treatment tactics. Obstetrics and gynecology. 2022. № 8. P. 154–162. (In Russ.). https://doi.org/10.18565/aig.2022.8.154-162 . EDN QKRTJT.


Review

For citations:


Nepomnyashchaya S.L., Belousov A.M., Shostka K.G., Malkov V.A., Senchilo S.I., Basos A.S., Saveljeva T.V., Kharlov N.S., Dubrovin V.Yu. Gastrointestinal bleeding in deep infiltrative endometriosis. Grekov's Bulletin of Surgery. 2026;185(1):65-73. (In Russ.) https://doi.org/10.24884/0042-4625-2026-185-1-65-73

Views: 264

JATS XML


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 0042-4625 (Print)
ISSN 2686-7370 (Online)