Experimental perfusion device for preservation of donor’s liver
https://doi.org/10.24884/0042-4625-2017-176-3-88-92
Abstract
OBJECTIVE. The authors aimed to develop complex perfusion medical device in order to successfully maintain viability of donor liver until transplantation. MATERIAL AND METHODS. Experimental perfusion device for normothermic perfusion donor’s liver was developed and tested in the Central Research and Experimental-design Institute of Robotics and Technical Cybernetics. RESULTS. The pre-clinical tests were performed on porcine liver. It was demonstrated that normothermic machine perfusion could restore liver function after 30 minutes of warm ischemia time and provide normalization of biochemical parameters of organ functioning.
About the Authors
S. F. Bagnenko
I. P.Pavlov First St. Petersburg State Medical University
Russian Federation
Russian Federation
O. N. Reznik
I. P.Pavlov First St. Petersburg State Medical University; I. I. Dzhanelidze St. Petersburg Research Institute of Emergency Medicine
Russian Federation
Russian Federation
A. E. Skvortsov
I. P.Pavlov First St. Petersburg State Medical University
Russian Federation
Russian Federation
A. V. Lopota
Central Research and Experimental-design Institute of Robotics and Technical Cybernetics
Russian Federation
Russian Federation
N. A. Gryaznov
Central Research and Experimental-design Institute of Robotics and Technical Cybernetics
Russian Federation
Russian Federation
V. V. Kharlamov
Central Research and Experimental-design Institute of Robotics and Technical Cybernetics
Russian Federation
Russian Federation
G. S. Kireeva
Central Research and Experimental-design Institute of Robotics and Technical Cybernetics
Russian Federation
Russian Federation
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Review
For citations:
Bagnenko S.F., Reznik O.N., Skvortsov A.E., Lopota A.V., Gryaznov N.A., Kharlamov V.V., Kireeva G.S. Experimental perfusion device for preservation of donor’s liver. Grekov's Bulletin of Surgery. 2017;176(3):88-92. (In Russ.) https://doi.org/10.24884/0042-4625-2017-176-3-88-92
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