An analysis of the treatment results was made in 447 patients with closed abdominal injury combined with liver damage. An individualized treatment-and-diagnostic program considering the data of field surgery- MT scale was applied in victims with closed abdominal trauma with liver damage. At the same time the classification E. Moore et.all (1990) for liver injuries was used for assistance. The indications for endovideosurgical homeostasis, a primary suture of liver wound and the hepatic resection were determined. The indications for packing the liver wound were specialized using strategy of «Damage control». An application of given individualized surgical strategy allowed reduction of the lethality level from 32,3% to 17,1% in the case of closed abdominal trauma with liver damage.

Changes of immune status were studied in patients with acute pancreatitis. The presence of expressed secondary immunodeficiency was determined in patients with acute destructive pancreatitis. The Ronkoleykin immunomodulator was used to correct the immune status. The authors obtained the positive results. An application of Ronkoleykin immunomodulator allowed decrease of the postoperative lethality with a high degree of reliability (p<0,01).

There is a number of factors such as the thyroidectomy and limiting subtotal thyroid resection against the background of euthyroidism and initial hypothyroidism (in any extent of operation) which leads to the prediction of early postoperative hypothyroidism origin during 10 days of the postoperative period. The early postoperative hypothyroidism is accompanied by activation processes of lipid peroxide oxidation and at the same time by reduction of antioxidant protection.

The ultrasonic signs of focal formations have a defining value for indication of fine-needle aspiration biopsy of thyroid nodules. The size and dynamics of growth aren’t so important. The evaluation of indications for performing a thyroid nodules biopsy was made in 6403 patients. It was proved that the size of thyroid nodules hadn’t any value for the indications and technique of aspiration biopsy. It was stated that a subjectivity assessment, many errors and parameters variety took place in clinical and ultrasound examination in the case of thyroid nodules changes. Indications for biopsy based on the size of nodules hadn’t any theoretical or practical value. The indications according to TIRADS system are reasonable. Their application considerably improved obtaining an informative material and increased the probability of thyroid tumor detection.

The article presents the results of investigation and treatment of 124 patients with neuroendocrine tumors of the pancreas (NET P): insulinima (68 cases), gastrinoma (43 cases), rare forms of tumor (13 patients). It was stated that clinical manifestations of NET P resembled the signs of neurological and gastroenterological diseases. Thus, the terms of detection would be prolonged during pre-admission stage and this validated the reasonability of well-timed application of current laboratory methods of diagnostics. An appropriate clinic neuroendocrine syndrome could be confirmed in 93-96% of patients. The authors showed that available diagnostic technique of NET P were the helical computer tomography and endoscopic ultrasound study with sensitivity 75% and 91%, respectively. It was rational to complete study with the data of intraoperative sonography for final tumor localization and its assessment in relation to the connection with pancreas duct and vessels. At the same time, it could be used in case of suspicion to multiple neoplasia. Angiography in combination with arterial-stimulated blood sampling from the hepatic vein and positron emission tomography with 18-fluorodeoxyglucose were the additional methods of diagnostics concerning the main forms of limited hyperinsulinism and generalized forms of NET P. Immunohistochemical study of removed pancreas tumor was the main method of morphological verification of the diagnosis and it’s used to develop the further strategy of postoperative treatment for patients. The surgical method of treatment of patients with NET P allowed elimination of clinical laboratory manifestations of neuroendocrine syndrome and getting general cumulative 5-year survival (69,3±4,7%) of radically operated patients.

The complex clinical and radiation examination was made in 135 victims with craniocerebral trauma and in 120 patients with primary tumors of the brain. All observations evaluated the index of transversal dislocation of the brain. It included derivative of volume parameter of intracranial supratentorial substratum, the value of dislocation of ventricular system and its width relatively to the septum pellucidum and at the same time the state of mind according to Glasgow coma scale. High diagnostic informativity of developed and certified index of transversal dislocation in different intracranial pathology allowed using the index for more wide application.

The article presents the results of treatment of 95 patients with iatrogenic damages and perforations caused by other reasons and spontaneous rupture of the esophagus. A defect of the esophagus was formed in thoracic part in 67,4% cases. Combined suppurative complications such as a neck phlegmon, mediastinitis, pleural empyema, pericarditis, pneumonia and lung abscess occurred in prevalent majority of patients. Surgical interventions were performed through cervical, thoracotomical and laparoscopical accesses. Different plastic methods of covering sutures of the esophagus were used in conditions of suppurative inflammation in 33 patients. An inconsistency of sutures was noted in 6 (18,2%) cases. Postoperative lethality consisted of 34,6% in spontaneous rupture of the esophagus and it was 11,9% in case of other damages.

The article presents the experience of treatment of newborn children and infants with congenital malformations of the lung and mediastinum, which required a surgery. Children (138 cases) were treated during recent 18 years. There was a prevalence of full-term infants (73%). Fetal malformations were diagnosed in prenatal period in majority of cases. Computed tomography was the main method of diagnostics after delivery. Children (110 cases) were operated out of 138. Children with extrapulmonary sequestration didn’t undergo surgery in case of absence of clinical manifestations. The authors made a conclusion that malformations of the lung and mediastinum should be included in number of differentiated diseases in case of respiratory distress syndrome in newborn children. The indications to early surgery should be the danger of contamination and malignant transformation, presence of intrathoracic tension syndrome in neonatal period.

An analysis of 19 cases of meningoencephalitis was made in infants aged under one year old. The disease was complicated by chronic subdural hematomas in 11 patients and by hydrocephalus in 8 patients. The article presents the strategy, treatment results and diagnostic procedures volume. Based on their work, the authors made a conclusion that meningoencephalitis required an emergency neurosurgical interference in order to avoid complications in convalescence period.

Traumatic diaphragmatic hernias could be clinically apparent and diagnosed after months and years after trauma. Bilateral ruptures of the diaphragm rarely appeared. Patients (46 cases) with diaphragmatic hernias were treated at the period from 1998 to 2010. The rate of diaphragmatic hernias consisted of 41,3%, bilateral post-traumatic hernias was noted in 2,2%. The article presents a follow-up study of bilateral diaphragmatic hernia, which was formed on the left (after 1 year) and on the right after 5 years. Diagnosis was supported by radiographic contrast research and computed tomography data. The stomach and omentum were displaced to the pleural cavity on the left, the transversely colon and omentum had a shift on the right. Thoracotomy and diaphragm plasty were performed in both cases. Hernial orifice was located in the area of esophageal opening and crura of diaphragm. It is necessary to increase clinical suspicion in relation to possibility of diaphragmatic hernia origin after severe closed trauma.

The article made a comparative assessment of traumatic injury of open hand-assisted laparoscopic anterior resection of the rectum in lateral and spinal positions. The presented technique of hand-assisted laparoscopic colon and rectal surgery is simple. There are advantages in case of obesity presence (IMT more than 30 kg/m²), in significant shortening of the mesocolon and mesentery, high fixation of splenic flexure and intimate fixation of the spleen, in case of bad preparation of the bowels in partial intestinal obstruction or in case of emergency operation, big cancer size, expressed perifocal inflammation. A comparative analysis of dynamics of hormone stress content and metabolism (cortisol, adrenaline, thyrothrophic hormone) showed their expressed increase in blood during operation after traditional surgery. Less stressed reaction was noted after hand-assisted surgery, especially in overweight patients. An application of low invasive method allowed reduction of hemorrhage, pain syndrome, terms of patient’s activation and restoration of intestinal motility after operation.

The article presents an initial Russian experience of video-thoracoscopic bronchoplastic lobectomies performed in 2 clinical cases of centric lung tumors. The upper bronchoplastic lobectomies with right lymphodissection were carried out on two patients in 2012. Complications weren’t observed in intraoperative and postoperative periods. There wasn’t relapse during two years after operation. Thus, the authors came to conclusion that thoracoscopic bronchoplastic lobectomies turned out to be safe and effective interventions in individual patients with centric tumor location, which wasn’t extended outside mouth of the lobar bronchus. The choice of candidates for thoracoscopic bronchoplasty was made using video-bronchoscopy, angio-computer tomography of the thorax and PET. This allowed avoiding an invasive staging and excluded patients with substantial extra-bronchial lesions.

The author considers the problems for surgeons such as maintenance of trachea and the esophagus integrity, bleeding prophylaxis, damage prevention of recurrent nerves and parathyroid glands. The article proposed the measures of the edematous syndrome prevention in early postoperative period.

The authors present the results of investigation of 42 patients with salivary gland dysfunction after radioactive iodine-131 ablation therapy concerning papillary thyroid carcinoma. Clinical manifestations of postradial sialodenitis with secretory insufficiency of different degree were revealed. These side effects required an application of the special therapy.

The authors present immediate and long-term results of treatment of 117 patients with superior thoracic outlet syndrome (STOS). There were different reasons for compression of neurovascular fascicle in outlet of the thorax. The costaclavicular syndrome was a reason in 48 patients, additional cervical ribs had 36 patients. Skalenus syndrome was noted in 26 cases, rudimentary cervical ribs or hypertrophy of cervical vertebrae C7 had 7 patients. Raynaud’s syndrome took place in 19 cases. The required volume of diagnostic procedures and surgical treatment of STOS were determined according to the cause of the syndrome. Differentiated approach to the different forms of STOS was used in relation to dominant symptoms of the disease and reasons for compression of neurovascular fascicle. This allowed getting positive results in majority of patients (90,4%) in long-term period.

The investigation based on a retrospective analysis of the treatment results of Fournier’s gangrene (FG) in 27 patients aged from 34 till 82 years old. There were 27 patients. Diseases of colorectal zone were the nosological reasons of FG in 15 patients. Diseases of urogenital tract had 10 patients with FG. The development of FG was determined by closed trauma (1 patient) and a gunshot wound of the perineum and the scrotum in one patient. The slowly progressive (limited) forms of the disease were noted in 15 patients, although the rapid progressive (extensive) forms were in 12 patients. All the patients had the clinical manifestations of the disease and at the same time laboratory indices indicated a presence of generalized infection and they were characterized by symptoms of systemic inflammatory response syndrome (SIRS). There were 6 patient, who died out of 27.The lethality consisted of 22,2%. The reasons of the death were an infection- toxic shock (1 case), a progressive endotoxicosis (3 cases) and a pulmonary artery thromboembolism (2 cases). The results obtained testified that early diagnostics and the active strategy with radical surgical d-bridement of necrotic suppurative foci combined with programmed (staged) sanitation necrosectomy, complex system of local wound treatment, the rational antibacterial therapy, a task-specific and syndrome correction of dyscrasia could be the actual ways to improve the treatment results in patients with FG.

An analysis of the scientific data was made. It was used the literature devoted to the intraoperative visualization of the sentinel lymph nodes in patients with lung cancer. Correct detection of such lymph nodes with following pathologic investigation allowed limiting the volume of lympho-dissection in a number of patients. There is the possibility of maximal in-depth study of the sentinel lymph nodes by purposeful application of most sensible pathologic and molecular methods for detection their micro-metastatic lesions. At the same time the treatment strategy and prognosis could be determined. The authors present the results of an application of dye techniques, radioactive preparation and fluorescence imaging for sentinel lymph node detection. Advantages and disadvantages of the methods are shown in the article. There are validated the prospects of technical development, study of information value of new applications and the most perspective method of fluorescence indocyanine green visualization by lymph outflow.